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| Date & Time | Favorite | Spread | Underdog | Total | Money Odds |
| 10/27 8:25 ET | At Tennessee | -3.5 | Jacksonville | 46.5 | -$ +$ |
| 10/30 9:30 AM | Cincinnati (At Twickenham) | -3 | Washington | 46 | -$ +$ |
| 10/30 4:25 ET | At Atlanta | -3 | Green Bay | 52.5 | -$ +$ |
| 10/30 1:00 ET | At Houston | -3 | Detroit | -$ +$ | |
| 10/30 1:00 ET | Seattle | -3.5 | At New Orleans | Off | -$ +$ |
| 10/30 1:00 ET | New England | -5.5 | At Buffalo | 47.5 | -$ +$ |
| 10/30 1:00 ET | NY Jets | -3 | At Cleveland | Off | -$ +$ |
| 10/30 1:00 ET | At Tampa Bay | -1 | Oakland | 49.5 | -$ +$ |
| 10/30 1:00 ET | Kansas City | -2.5 | At Indianapolis | 49.5 | -$ +$ |
| 10/30 4:05 ET | At Denver | -6 | San Diego | Off | -$ +$ |
| 10/30 1:00 ET | At Carolina | -1.5 | Arizona | Off | -$ +$ |
| 10/30 8:30 ET | At Dallas | -4.5 | Philadelphia | 43.5 | -$ +$ |
Monday Night Football Odds
| Minnesota | -4.5 | At Chicago | Off | -$ +$ |
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