Guardians vs Yankees Prediction, Picks & Best Bet for Today’s MLB Game

Caley's pick: Don't expect a letup from Yankees SP Max Fried against a weak-hitting Guardians offense tonight.

Andrew Caley - Senior Betting Analyst at Covers.com
Andrew Caley • Senior Betting Analyst
Jun 5, 2025 • 16:05 ET • 4 min read
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This article contains predictions for an old game!

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New York Yankees MLB Max Fried
Photo By - Imagn Images. New York Yankees starting pitcher Max Fried in MLB action.

The New York Yankees and the Cleveland Guardians face off in the rubber match of their three-game set tonight.

My Guardians vs. Yankees predictions believe the Bronx Bombers have a significant edge on the mound in this one, as they hand the ball to Max Fried.

Check out my MLB picks for this American League battle with first pitch set for 7:05 pm ET at Yankee Stadium on Thursday, June 5.

Guardians vs Yankees prediction

My Guardians vs Yankees best bet: Max Fried Over 18.5 outs recorded (+150 at bet365)

When Gerrit Cole got hurt in the offseason, questions were raised about the New York Yankees' rotation. But Max Fried seamlessly stepped into the role of team ace.

The left-hander has dominated during his first season in pinstripes. The 31-year-old Fried enters tonight’s matchup against the Cleveland Guardians, pitching to a 1.92 ERA while limiting opponents to a .205 batting average.

And even though he is coming off his worst start of the season, I think we can give him some leeway. One, his last start was against the Dodgers. Two, it was the first time in 12 starts this season where he allowed more than two earned runs. 

Fried has also been a workhorse. He is averaging 94.1 pitches and facing nearly 25 batters per start. That has resulted in him going at least six innings eight times this season.

I’m betting he’s got another long outing in him tonight.

The Guardians' bats have been inconsistent for most of the season, resulting in them ranking 21st in scoring at 4.02 runs per game. They also rank dead last in expected batting average. Lefties in particular have given them problems. Cleveland enters this matchup ranked 25th in OPS and 23rd in wRC+ when facing southpaws this season.

Fried’s outs recorded prop is sitting at 18.5, but the price on the Over of +150 is good enough to take a shot here. He’s also eclipsed this number in seven of his last 10 starts.

Fried should be efficient when working his way through this Guardians lineup and go over this number once again. 

Guardians vs Yankees same-game parlay (SGP)

Max Fried to record the win

Aaron Judge Over 0.5 RBI

Jhonkensy Noel Under 0.5 hits

Let’s put a twist on this same-game parlay by putting Fried to record a win instead. He has seven wins already this season and will have a great shot to make it eight.

That’s in part because Guardians’ starter Slade Cecconi is struggling. The 25-year-old right-hander is pitching to a 6.61 expected ERA while surrendering a .285 expected batting average to opponents. 

Let’s not overcomplicate this. Aaron Judge continues to rake at another level. Two more hits last night brought his average back up to .389. He has driven in 50 runs this season, and I like him to add to that tonight.

Fried on the mound also means a tough night might be in store for Jhonkensy Noel. The Guardians outfielder is hitting just .143 vs. left-handed pitching this season. Under 0.5 hits for Noel.

Guardians vs Yankees odds

Guardians vs Yankees live odds

Guardians vs Yankees opening odds

  • Moneyline: Cleveland +205 | New York -250
  • Run line: Cleveland +1.5 (-105) | New York -1.5 (-115)
  • Over/Under: Over 8.5 | Under 8.5

Guardians vs Yankees trend

The Guardians have hit the Under in 15 of their last 24 games for +5.95 Units and a 22% ROI. Find more MLB betting trends for Guardians vs. Yankees.

How to watch Guardians vs Yankees and game info

Location Yankee Stadium, Bronx, NY
Date Thursday, 6-5-2025
First pitch 7:05 p.m. ET
TV CLEG, YES
Guardians starting pitcher Slade Cecconi
(1-1, 5.28 ERA)
Yankees starting pitcher Max Fried
(7-1, 1.92 ERA)

Guardians vs Yankees latest injuries

Guardians vs Yankees weather

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Andrew Caley
Senior Betting Analyst

When his dreams of becoming the next Steve Nash died, all Andrew "Taco" Caley wanted to do was write about sports, something he's been doing at Covers for more than a decade. A Journalism School grad from Holland College in Charlottetown, PEI, Andrew previously worked at The Chronicle Herald and Star Metro, but knew in his heart that his future lay in sports. He began at Covers as a news editor and has now done everything under the sun when it comes to content. His work has been seen on TSN, Sportsnet, VSiN, and CBS. These days Andrew's betting expertise is focused on his favorite teams; the Toronto Blue Jays and Toronto Raptors. He's also an avid college football fan and bettor. He can't be friends with you if you don't appreciate a Service Academy Under. You can also call him Covers Sixth Man, as he regularly steps up to guest host Before You Bet and our MLB and NCAAF release shows. The sportsbook where he does the bulk of his betting is bet365 thanks to its numerous prop betting options and competitive odds. His best advice? Find the balance between the numbers and what you see on the playing field. Then find the best price using multiple books. And don’t ask him where the nickname Taco comes from. It's not an interesting story. Seriously.<

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