49ers vs Seahawks Week 8 picks and predictions

Tyler Lockett torched the Cardinals in Week 7 for 200 yards on 15 receptions, adding three touchdowns. The 49ers may struggle to match Seattle's offensive punch, given all their injuries.

Andrew Caley - Senior Betting Analyst at Covers.com
Andrew Caley • Senior Betting Analyst
Oct 26, 2020 • 16:30 ET
Tyler Lockett NFL Seattle Seahawks
Photo By - USA TODAY Sports

However you would describe the NFC East this season, well, the NFC West is the exact opposite of that. All four teams look like playoff contenders and we are set up with another sweet divisional showdown for NFL bettors to sink their teeth into as the Seattle Seahawks take on the San Francisco 49ers.

The Seahawks are 3-point home favorites against the defending NFC champs, who not only will have to survive MVP candidate Russell Wilson, but their latest wave of injuries as well.

These are our NFL free picks and predictions for 49ers vs. Seahawks on November 1.

San Francisco 49ers at Seattle Seahawks betting preview

Weather

It should be a nice afternoon for fall football in Seattle. The forecast is calling for clear skies with temperatures in the mid to low-50s for the game with minimal wind. Be sure to monitor the gametime conditions with our NFL weather info.

Key Injuries

49ers: Raheem Mostert RB (Out), Deebo Samuel WR (Out), Jeff Wilson Jr. RB (Out), Kwon Alexander LB (Out), Jaquiski Tartt S (Out), Richard Sherman DB (Out).
Seahawks: Chris Carson RB (Out), Carlos Hyde RB (Out), Shaquil Griffin CB (Out), Jamal Adams S (Out), Mike Iupati G (Out).
Find our latest NFL injury reports.

Betting trend to know

The 49ers have not been kind to their backers when they visit the Seahawks, going just 2-6-1 ATS in their last nine trips to Seattle. Find more NFL betting trends for 49ers vs. Seahawks.

Against the spread (ATS) pick

The Seahawks have been making their backers sweat all season. Despite a 4-0 record ATS to start the year, only their season-opening win against the Falcons was sweat-free. The other three, Seattle covered by an average of two points, and they have followed that up with back-to-back ATS losses, including last week’s game at Arizona where the Seahawks were a holding call away from the win and cover.

Now, they’ll have to deal with a 49ers team, that, despite a laundry list of injuries is still battling at 4-3 and have covered all three of their road games this season. But will that injury list finally be too much in Seattle, where they have covered just twice in their last nine trips?

So. RB Raheem Mostert went down, again. No worries, Jeff Wilson Jr. steps up and goes for over 100 yards and three scores. But then Wilson hurts his ankle on his final TD run. Then WR Deebo Samuel had to come out with a hamstring injury. They join the likes of Nick Bosa, Dee Ford, Ezekiel Ansah, Richard Sherman, to just name a few, and all of a sudden it looks like Jimmy Garoppolo is on the set of “I Am Legend.”

Kyle Shanahan and the Niners always seem to have an RB or someone step up, and the defense is still putting up strong numbers despite all the injuries, but those might be hard to overcome this week, even though the Seahawks give up the most yards in the NFL. If there is one thing Seattle is OK at on defense, it's stopping the run, where they rank ninth in DVOA. The Seahawks also just added former Bengal Carlos Dunlap to help out their pass rush.

Oh. The Seahawks also have this guy, he’s pretty good. Not sure if you’ve heard of him, his name is Russell Wilson and he’s the frontrunner for NFL MVP. This one feels like another classic NFC West sweat, but the Seahawks have more healthy weapons right now, and the defense should do just enough to secure the win and cover.

PREDICTION: Seattle -3 (-110)

 

Over/Under pick

The total in this matchup is quite indicative of 2020. At 53.5, it's the highest total these teams have played at in the last 10 meetings. By 6.5 points. That’s quite a jump.

Last year, these NFC West rivals went 1-0-1 O/U, but the Over went to overtime and they combined to score 49 points in those two meetings. So, can we justify a total this high? 

It is likely this high due to Russell Wilson playing so well, and the Seahawks’ D being so porous. Wilson deserves all the MVP chatter he is garnering. The Seahawks’ QB has thrown for 1,890 yards with 22 touchdowns and six picks while completing over 71 percent of his passes. But the Niners always play Wilson tough, allowing him to pass for a combined 412 yards in their two meetings last season.

In fact, it’s kind of incredible that San Francisco can rank in the Top 10 in defensive DVOA, and Top 5 in yards and points allowed considering all the injuries they’ve had to deal with. But they have been a little worse against the pass ranking 13th in DVOA.

And while the Seahawks D has struggled, all the injuries mean the Niners have taken a step back on offense this season, and Jimmy G hasn’t looked ready to carry the team. This total looks inflated so we’re grabbing the Under before it gets much lower.

PREDICTION: Under 53.5 (-110)

Player Prop Picks

It seems like TE George Kittle is one of the only healthy people on the 49ers’ offense and my bet is Jimmy Garoppolo leans on him big time in this matchup. 

The star TE has seen 40 targets in his last four games, but the production has been a bit hit or miss. In two of those games, he had seven or more receptions and went over 100 yards, while in the other two he totaled just nine catches for 99 yards. Last year, in Kittle’s long game against the Seahawks, he hauled in all seven of his targets for 86 yards. 

Plus, the Seahawks secondary is banged up, including Jamal Adams, who is questionable with a groin injury. While Seattle hasn’t given up a ton to catches and yards to TEs, when they do it comes in chunks, allowing nearly 15 yards per reception to TEs. 

But I mean, at the end of the day, there is no one else. Bet Kittle to have a big day.

PREDICTION: George Kittle Over 6.5 Receptions (+117) AND Over 65.5 Yards (-119)

49ers vs Seahawks betting card

  • Seattle -3 (-110)
  • Under 53.5 (-110)
  • George Kittle Over 6.5 Receptions (+117)
  • George Kittle Over 65.5 Receiving Yards (-119)
NFL Parlays

Did you know that if you parlayed this week’s NFL 49ers vs. Seahawks picks, you could win $135.55 on a $10 bet?

Use our NFL parlay calculator to create your own parlays and see their potential payouts.

Where can I bet on the NFL?

You can bet on NFL odds at every online and casino sportsbooks, including NFL moneylines, spreads, Over/Under totals and a ton of NFL prop odds. Head over to our best-suggested sportsbooks for the top spots to bet on NFL odds in your area.

Pages related to this topic

Senior Betting Analyst

When his dreams of becoming the next Steve Nash died, all Andrew “Taco” Caley wanted to do was write about sports, something he’s been doing at Covers for more than a decade. A Journalism School grad from Holland College in Charlottetown, PEI, Andrew previously worked at The Chronicle Herald and Star Metro, but knew in his heart that his future lay in sports. He began at Covers as a news editor and has now done everything under the sun when it comes to content. His work has been seen on TSN, Sportsnet, VSiN, and CBS.

These days Andrew’s betting expertise is focused on his favorite teams – the Toronto Blue Jays and Toronto Raptors. He’s also an avid college football fan and bettor. He can’t be friends with you if you don’t appreciate a Service Academy Under. You can also call him Covers’ Sixth Man, as he regularly steps up to guest host Before You Bet and our MLB and NCAAF release shows.

The sportsbook where he does the bulk of his betting is bet365 thanks to its numerous prop betting options and competitive odds. His best advice? Find the balance between the numbers and what you see on the playing field. Then find the best price using multiple books. And don’t ask him where the nickname Taco comes from. It’s not an interesting story. Seriously.

Popular Content

Legal Canadian sports betting

Best Canadian betting sites Ontario sports betting
Covers 25 Years Logo Established in 1995,
Covers is the world
leader in sports
betting information.
Covers is verified safe by: Evalon Logo GPWA Logo GDPR Logo GeoTrust Logo Evalon Logo