Colts vs Broncos Predictions and Picks for NFL Week 15

While the Indianapolis Colts can be difficult to back, our expert NFL predictions have found an edge behind the Colts' defense and the big arm of Anthony Richardson.

Jeremy Jones - Betting Analyst at Covers
Jeremy Jones • Betting Analyst
Dec 14, 2024 • 14:04 ET • 4 min read

NFL

Match starts: 22 hrs
DEN
69 %
IND
31 %
EXPERT PICK - SPREAD
Indianapolis +4.5 (-125) Indianapolis +4.5 (-125)
Read Analysis
Anthony Richardson of the Indianapolis Colts
Photo By - Imagn Images.

Two teams coming off a bye week will be meeting in what may be the most important game this week for playoff implications when the 6-7 Indianapolis Colts travel to the Mile High City to take on the 8-5 Denver Broncos

The Colts have won two of their past three games and need a win over the Broncos to stay alive in the Wildcard race. The Broncos have won three consecutive games and will almost guarantee themselves a playoff spot with a win here.

My selections for Colts vs. Broncos predict a game that will come down to the wire. Find out why I am backing the road team in my NFL picks for Sunday, December 15.

Colts vs Broncos prediction

My best bet
Indianapolis Colts +4 (-105 at BetMGM)

My analysis
If the Indianapolis Colts win this game, their playoff chances will increase to 56%, however, it will fall all the way down to 7% with a loss. Meanwhile, the Denver Broncos' playoff chances will jump all the way to 88% with a win and fall to 46% with a loss. This is such a huge game for the playoff picture in the AFC.

This is a dangerous game to be backing the Colts because the Broncos are 7-0 this season against teams with a losing record, and the Colts are 1-4 against teams with a winning record. However, there are plenty of reasons to believe the Colts can cover this spread and possibly even win straight up. 

I am not a big believer in Anthony Richardson as a franchise quarterback, but he certainly can air it out deep and has a nice advantage against this Broncos defense. Richardson has attempted a pass of 10+ air yards on 47.9% of his attempts this season, which is 8.4% higher than any other quarterback in the NFL this year.

The Broncos have allowed the ninth-highest completion percentage on downfield passes this season at 52.3%.

While the Colts' defense has been very up and down all season, the addition of DeForest Buckner has made a big difference. Since he returned from injury in Week 8, he has generated the second most pressures among all defensive tackles in the NFL. As great as Bo Nix has been this season as a rookie, he has struggled under pressure.

Nix has just a 51.6 quarterback rating and only a 43.3% completion percentage against pressure. If the Colts can get pressure without needing to blitz and play their usual Cover 3 defense, they could force some mistakes and pull out the win in Denver.

Colts vs Broncos same-game parlay

Colts +4

Josh Downs Under 51.5 receiving yards

Anthony Richardson Over 187.5 passing yards

To go along with the Colts covering, I am going to throw in a couple of player props. To start, I believe this will be a bad game for Josh Downs. He aligns in the slot on 64.9% of his snaps this season, and the Broncos have allowed the fifth-fewest yards per target to slot receivers this season.  

Finally, I will add Anthony Richardson to rack up the passing yards through the deep ball. Since we took one of his receivers to go Under, this will greatly boost our odds. However, he is going to get his yards with guys like Michael Pittman, Alec Pierce, and even Adonai Mitchell on deep balls in this game and not Downs underneath.  

Learn how to bet a same-game parlay with these helpful tips and strategies.

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More NFL picks and odds from Covers


Colts vs Broncos odds

Colts vs Broncos live odds

Colts vs Broncos opening odds

  • Spread: Indianapolis +4 (-105) | Denver -4 (-115)
  • Moneyline: Indianapolis (+165) | Denver (-200)
  • Over/Under: Over 44 (-110) | Under 44 (-110)

Odds courtesy of BetMGM

Colts vs Broncos spread and Over/Under analysis

  • The spread was Colts -2.5 before the season but opened at Broncos -4.5 this week and has roller-coastered throughout the week before landing at -4 as of Saturday afternoon
  • The underdog has covered six of the past eight matchups between these two teams.
  • The total was 44.5 before the season and re-opened at 43.5 this week and, after an early drop, has climbed back up to 44 as of Saturday afternoon.
  • Each of the past three matchups between these two teams has gone Under the total.

Colts vs Broncos betting trend to know

The Indianapolis Colts have covered the 1Q Spread in 13 of their last 20 games. Find more NFL betting trends for Colts vs. Broncos.

Colts vs Broncos game info

Location: Empower Field at Mile High, Denver, CO
Date: Sunday, 12-15, 2024
Kickoff: 4:25 p.m. ET
TV: CBS

Colts vs Broncos latest injuries

Colts vs Broncos weather

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Jeremy Jones - Covers
Betting Analyst

Jeremy Jones was born and raised in Lexington, Kentucky and has been a massive Wildcats fans since the moment he came into the world. He wrote his first sports article at the tender age of 11 after attending a local AHL hockey game, and a few years later was writing professionally for sites such as Sports Rants, BetAmerica, and TwinSpires.

Jeremy holds a Masters in Sports Administration from Eastern Kentucky University and utilizes all seven betting options available in Kentucky to shop for odds and promos and find the greatest EV in every wager he places.

His best piece of sports betting advice is to stick to consistent unit sizes for every wager. He acknowledges there will occasionally be a bet that has a huge EV and you can play multiple units in one bet, but cautions against raising your unit size, because you can quickly lose all your winnings if you hit a minor cold streak.

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