NFL Odds Week 12: Lines & Spreads For Every Game

NFL Week 12 Odds

Matchup	Spread	Moneyline	Over/Under
Steelers vs Browns	Browns +3.5	Steelers -200 Browns +165	37
Cowboys vs Commanders	Commanders -10.5	Cowboys +400 Commanders -550	45
Buccaneers vs Giants	Giants +6	Buccaneers -275 Giants +225	41.5
Chiefs vs Panthers	Panthers +11	Chiefs -700 Panthers +500	43
Vikings vs Bears	Bears +3.5	Vikings -185 Bears +155	39.5
Patriots vs Dolphins	Dolphins -7.5	Patriots +310 Dolphins -400	46
Titans vs Texans	Texans -8	Titans +340 Texans -450	40.5
Lions vs Colts	Colts +7.5	Lions -400 Colts +310	50.5
Broncos vs Raiders	Raiders +6	Broncos -275 Raiders +225	41
49ers vs Packers	Packers -2	49ers +105 Packers -125	47.5
Cardinals vs  Seahawks	Seahawks +1	Cardinals -115 Seahawks -105	47.5
Eagles vs  Rams	Rams +3	Eagles -155 Rams +130	49
Ravens vs Chargers	Chargers +3	Ravens -155 Chargers +130	51

Lines from BetMGM as of 11-21
Bye week: Atlanta, Buffalo, Cincinnati, New Orleans, New York, Jacksonville

With six teams on a bye, the NFL odds for Week 12 feature one of the season's lightest slates but is still loaded with plenty of divisional matchups.

Kicking off the week is an AFC North affair between the Pittsburgh Steelers and Cleveland Browns on TNF, while there are also Cowboys/Commanders, Vikings/Bears, and Cardinals/Seahawks among the seven divisional clashes this week.

The schedule is highlighted by the 49ers venturing to Lambeau to face the Packers, as well as a Monday Night Football game between the Ravens and the Chargers. 

Steelers vs. Browns odds (Thursday, 8:15 p.m. ET, Prime)

Opening line

• Browns +4
• Over/Under 41.5
• View full Steelers vs. Browns odds and matchup
• Read our Steelers vs. Browns picks and predictions

The Steelers head to Cleveland for Thursday Night Football off a huge divisional win over the Ravens in Week 11. Pittsburgh has looked great with Russell Wilson under center and opened against Jameis Winston and the struggling Browns as 5.5-point favorites. However, that has dropped two points to 3.5. The total hit the betting board at 40 on Sunday afternoon and has done nothing but crater. It sits between 36.5 and 37 on Thursday morning.

Also see: full Thursday Night Football odds

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Cowboys vs. Commanders odds (Sunday, 1:00 p.m. ET, FOX)

Opening line

• Commanders -9.5
• Over/Under 45
• View full Cowboys vs. Commanders odds and matchup
• Read our Cowboys vs. Commanders picks and predictions (coming soon)

The Commanders opened at -9.5, but that quickly jumped another point after the Cowboys got pantsed in the second half of their Monday Night Football showdown with the Texans. The total is at 45.5 after opening at 45.

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Buccaneers vs. Giants odds (Sunday, 1:00 p.m. ET, CBS)

Opening line

• Giants +3
• Over/Under 43
• View full Buccaneers vs. Giants odds and matchup
• Read our Buccaneers vs. Giants picks and predictions (coming soon)

The Bucs and Giants are both coming off byes in Week 11 and will butt heads Sunday afternoon at the Meadowlands. The G-Men come into this contest on a five-game losing skid, while Tampa Bay has dropped four in a row (against a gauntlet of difficult opponents). Books opened this matchup with the Bucs as 3.5-point road favorites and a total of 43. Tampa is now -5.5 and the total is 41.5.

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Chiefs vs. Panthers odds (Sunday, 1:00 p.m. ET, CBS)

Opening line

• Panthers +11.5
• Over/Under 41
• View full Chiefs vs. Panthers odds and matchup
• Read our Chiefs vs. Panthers picks and predictions (coming soon)

The Panthers are coming off a bye week and will host the Chiefs in Week 12. Kansas City is fresh off its first loss of the season in a very entertaining contest in Buffalo. Sportsbooks opened the Chiefs as huge 11.5-point road favorites with a total of 41.5. Those marks sit at -11 and 43 as of Thursday morning.

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Vikings vs. Bears odds (Sunday, 1:00 p.m. ET, FOX)

Opening line

• Bears +5
• Over/Under 40.5
• View full Vikings vs. Bears odds and matchup
• Read our Vikings vs. Bears picks and predictions (coming soon)

The Vikings head to Soldier Field in Chicago for their second consecutive road game on Sunday afternoon. Minnesota easily handled a bad Tennessee Titans side in Week 11, while the Bears lost a heartbreaker to the Packers on a game-ending blocked field goal. Sportsbooks opened the Vikes as 4-point road favorites with a total of 40.5. Minnesota is now universally -3.5, with the total shrinking to between 39 and 39.5. 

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Patriots vs. Dolphins odds (Sunday, 1:00 p.m. ET, CBS)

Opening line

• Dolphins -6.5
• Over/Under 44
• View full Patriots vs. Dolphins odds and matchup
• Read our Patriots vs. Dolphins picks and predictions (coming soon)

The Patriots host the Dolphins at Gillette Stadium coming off a tough home loss in Week 11 against the Los Angeles Rams. The Dolphins handled their business in a big win over the Las Vegas Raiders and opened as 7.5-point road favorites in this AFC East showdown. That line is consistently available on Thursday with the odd Fins -7 juiced to around -120. The total hit betting boards at 45.5 and has been bet up to as high as 46.5. 

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Titans vs. Texans odds (Sunday, 1:00 p.m. ET, CBS)

Opening line

• Texans -8
• Over/Under 42.5
• View full Titans vs. Texans odds and matchup
• Read our Titans vs. Texans picks and predictions (coming soon)

The Texans smoked the Cowboys on Monday Night Football and have jumped as high as -9 on Thursday vs. the Titans after opening at -8. The total sits between 40.5 and 41 after opening at 42.5.

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Lions vs. Colts odds (Sunday, 1:00 p.m. ET, FOX)

Opening line

• Colts +6.5
• Over/Under 49
• View full Lions vs. Colts odds and matchup
• Read our Lions vs. Colts picks and predictions (coming soon)

The Lions, and their electric offense, head to Indianapolis to take on the host Colts. The Lions dismantled the Jacksonville Jaguars in Week 11 and will take on a Colts squad coming off a nice win over the New York Jets at Metlife Stadium. Books opened Detroit as 7.5-point road favorites with a total of 50.5. The spread is still at that consensus number while some books have dropped the total to 49.5.

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Broncos vs. Raiders odds (Sunday, 4:05 p.m. ET, CBS)

Opening line

• Raiders +3
• Over/Under 41.5
• View full Broncos vs. Raiders odds and matchup
• Read our Broncos vs. Raiders picks and predictions (coming soon)

The Broncos dismantled the visiting Atlanta Falcons, 38-6, in Week 11, while the Raiders looked uninspired in their loss in South Florida against the Dolphins. Denver started the betting week as 4-5-point road favorites with an opening total of 41.5. Broncos -5.5 was briefly the industry consensus but some books are offering -6 or even -6.5 on Thursday morning. The total is between 40.5 and 41.5.

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49ers vs. Packers odds (Sunday, 4:25 p.m. ET, FOX)

Opening line

• Packers -1.5
• Over/Under 48
• View full 49ers vs. Packers odds and matchup
• Read our 49ers vs. Packers picks and predictions (coming soon)

The 49ers lost a shocker in the final minute against the Seattle Seahawks in Week 11, while the Packers continued their dominance over the Chicago Bears with a one-point win at Soldier Field. The Packers opened the Week 12 betting period as 1-point home favorites and have only seen that number climb to -2.5 by Thursday morning. The total is 47.5 across the board.

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Cardinals vs. Seahawks odds (Sunday, 4:25 p.m. ET, FOX)

Opening line

• Seahawks -1
• Over/Under 48.5
• View full Cardinals vs. Seahawks odds and matchup
• Read our Cardinals vs. Seahawks picks and predictions (coming soon)

The Cardinals are coming off a Week 11 bye and will travel to Seattle to take on the Seahawks, who are coming off a shocking last-minute win over the 49ers. Sportsbooks opened the Hawks as 1-point home favorites, and some books remain at that number while others have flipped to Cardinals -1 on Thursday with a rogue pick 'em or two out there as well.

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Eagles vs. Rams odds (Sunday, 8:20 p.m. ET, NBC)

Opening line

• Rams +2.5
• Over/Under 47.5
• View full Eagles vs. Rams odds and matchup
• Read our Eagles vs. Rams picks and predictions (coming soon)

The Eagles are coming off a mini-bye after their convincing 26-18 win over the Commanders on Thursday Night Football in Week 11. The Rams had a nice road win over the Patriots but opened as 2.5-point home underdogs for this Sunday night matchup. Most books are now sitting Philly -3. The total for Sunday Night Football opened at 47.5 and sits between 48.5 and 49.5 after moving as high as 51.

Also see: full Sunday Night Football odds

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Ravens vs. Chargers odds (Monday, 8:15 p.m. ET, ESPN/ABC)

Opening line

• Chargers +3
• Over/Under 47
• View full Ravens vs. Chargers odds and matchup
• Read our Ravens vs. Chargers picks and predictions (coming soon)

The Ravens opened at -3 for this Monday Night matchup against the Chargers. That trimmed slightly to -2.5 across the board after Baltimore's loss to Pittsburgh and Los Angeles' SNF win over Cincinnati, though that half-point has been tacked back on at several books. The total opened at 47 but shot up to 50 on Wednesday and 51 on Thursday.

Also see: full Monday Night Football odds

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More weekly NFL odds content

• Week 1 odds
• Week 2 odds
• Week 3 odds
• Week 4 odds
• Week 5 odds
• Week 6 odds
• Week 7 odds
• Week 8 odds
• Week 9 odds
• Week 10 odds
• Week 11 odds
• Week 13 odds
• Week 14 odds
• Week 15 odds
• Week 16 odds
• Week 17 odds
• Week 18 odds

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