NFL odds Week 16
| Matchup | Spread | Moneyline | Over/Under |
|---|---|---|---|
 Broncosvs  Chargers |
Chargers -3 | Broncos +135 Chargers -160 |
42.5 |
 Texansvs  Chiefs |
Chiefs +2.5 | Texans -140 Chiefs +115 |
40.5 |
 Steelersvs  Ravens |
Ravens -6.5 | Steelers +225 Ravens -275 |
46.5 |
 Giantsvs  Falcons |
Falcons -10 | Giants +400 Falcons -550 |
42.5 |
 Patriotsvs  Bills |
Bills -14 | Patriots +600 Bills -900 |
46.5 |
 Lionsvs  Bears |
Bears +7.5 | Lions -375 Bears +300 |
46.5 |
 Brownsvs  Bengals |
Bengals -7 | Browns +260 Bengals -350 |
49.5 |
 Titansvs  Colts |
Colts -4.5 | Titans +180 Colts -225 |
42.5 |
 Ramsvs  Jets |
Jets +3 | Rams -165 Jets +140 |
47.5 |
 Eaglesvs  Commanders |
Commanders +4 | Eagles -190 Commanders +155 |
46.5 |
 Cardinalsvs  Panthers |
Panthers +4.5 | Cardinals -225 Panthers +180 |
46.5 |
 Vikingsvs  Seahawks |
Seahawks +2.5 | Vikings -144 Seahawks +122 |
45.5 |
 Jaguarsvs  Raiders |
Raiders -1.5 | Jaguars +100 Raiders -120 |
39.5 |
| 49ers vs  Dolphins |
Dolphins -2.5 | 49ers +115 Dolphins -140 |
46.5 |
 Buccaneersvs  Cowboys |
Cowboys +4.5 | Buccaneers -200 Cowboys +165 |
47.5 |
 Saintsvs  Packers |
Packers -12.5 | Saints +575 Packers -850 |
42.5 |
Lines as of 12-15
The NFL Week 16 odds carry a lot of weight.
The postseason push is in full swing with teams fighting for division titles, home-field advantage, and Wild Card tickets in the final three weeks of the regular season.
That intensity starts on Thursday when the Los Angeles Chargers host the Denver Broncos in a heavy AFC West matchup.
We have two Saturday showdowns, with the Kansas City Chiefs hosting the Houston Texans and a classic AFC North grudge match between the Pittsburgh Steelers and Baltimore Ravens.
Sunday’s slate is headlined by the Philadelphia Eagles and Washington Commanders in an NFC East encounter as well as an interesting NFC matchup between the Minnesota Vikings and Seattle Seahawks.
Week 16 comes to a close with the New Orleans Saints visiting Lambeau Field and the Green Bay Packers on Monday night.
Here are the opening NFL Week 16 odds and early adjustments.
Broncos vs Chargers odds (Thursday, 8:15 p.m. ET, Amazon Prime)
Opening line
- Chargers -3
- Over/Under 42
- View full Broncos vs. Chargers odds and matchup
- Read our Broncos vs. Chargers picks and predictions (coming soon)
The Chargers tumbled in Week 15 while the Broncos picked up a big home win, which leaves L.A. opening as a 3-point favorite for Thursday Night Football. These rivals are vying for a Wild Card spot in the AFC side of the tournament. This total opened at 42 points.
Also see: full Thursday Night Football odds
Texans vs Chiefs odds (Saturday, 1:00 p.m. ET, NBC)
Opening line
- Chiefs +1.5
- Over/Under 41
- View full Texans vs. Chiefs odds and matchup
- Read our Texans vs. Chiefs picks and predictions (coming soon)
All eyes are on Patrick Mahomes’ ankle in Week 16. He hobbled off the field in the Chiefs win at Cleveland on Sunday and is listed as day-to-day with one less day to rest up, as this game takes place on Saturday. Books opened Kansas City as a 1.5-point home underdog — padding the point spread in case Mahomes can’t play — and early action is trying to get out ahead of any updates, moving the number to Texans -2.5. This total hit the board at 41 points.
Steelers vs Ravens odds (Saturday, 4:30 p.m. ET, FOX)
Opening line
- Ravens -6.5
- Over/Under 46.5
- View full Steelers vs. Ravens odds and matchup
- Read our Steelers vs. Ravens picks and predictions (coming soon)
Baltimore and Pittsburgh have a Saturday showcase in Week 16, with the Ravens opening as 6.5-point home favorites. The status of Pittsburgh WR George Pickens is one to watch as he’s sat out the past two games. This total opened at 46.5 points. Cold and wind gusts up to 41 mph are in the extended forecast.
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Giants vs Falcons odds (Sunday, 1:00 p.m. ET, FOX)
Opening line
- Falcons -8.5
- Over/Under 41.5
- View full Giants vs. Falcons odds and matchup
- Read our Giants vs. Falcons picks and predictions (coming soon)
Opening line analysis coming soon!
Patriots vs Bills odds (Sunday, 1:00 p.m. ET, CBS)
Opening line
- Bills -12.5
- Over/Under 46.5
- View full Patriots vs. Bills odds and matchup
- Read our Patriots vs. Bills picks and predictions (coming soon)
The Bills are riding high off a huge win at Detroit on Sunday. Bookies opened Buffalo as a 13.5-point home chalk and that has already busted through the key number of two touchdowns, jumping to Bills -14.5. The Over/Under opened at 45.5 and is down to 44.5 O/U. The forecast for Orchard Park looks nasty on Sunday, with wind gusts flirting with 40 mph, snow, and “feels like” temperatures at 4 degrees.
Lions vs Bears odds (Sunday, 1:00 p.m. ET, FOX)
Opening line
- Bears +7.5
- Over/Under 46.5
- View full Lions vs. Bears odds and matchup
- Read our Lions vs. Bears picks and predictions (coming soon)
Opening line analysis coming soon!
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Browns vs Bengals odds (Sunday, 1:00 p.m. ET, FOX)
Opening line
- Bengals -6.5
- Over/Under 49.5
- View full Browns vs. Bengals odds and matchup
- Read our Browns vs. Bengals picks and predictions (coming soon)
The Bengals opened as 6.5-point home favorites in this Battle of Ohio and jumped to -7 with Cleveland RB Nick Chubb out with a broken leg. The total opened at 49.5 points with two offenses that want to push the ball deep. The extended forecast for Cincinnati calls for sub-freezing temperatures and wind gusts over 21 mph.
Titans vs Colts odds (Sunday, 1:00 p.m. ET, CBS)
Opening line
- Colts -5.5
- Over/Under 43.5
- View full Titans vs. Colts odds and matchup
- Read our Titans vs. Colts picks and predictions (coming soon)
The Colts opened as 5.5-point home favorites and money came in against Indianapolis, dropping the spread to -4.5. Colts WR Alec Pierce left Week 15 with a concussion. Tennessee will likely start QB Mason Rudolph after benching Will Levis this past Sunday. The Over/Under opened at 43.5 O/U.
Rams vs Jets odds (Sunday, 1:00 p.m. ET, CBS)
Opening line
- Jets +3
- Over/Under 46.5
- View full Rams vs. Jets odds and matchup
- Read our Rams vs. Jets picks and predictions (coming soon)
The L.A. Rams get a mini-bye after a big win last Thursday but now have to travel to the East Coast for an early kickoff in what looks to be some nasty winter weather. The forecast for East Rutherford calls for wind gusts up to 36 mph cooling temperatures to “feels like” 15 degrees. Los Angeles opened as a 3-point road favorite with the total climbing from 46.5 to 47.5 O/U.
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Eagles vs Commanders odds (Sunday, 1:00 p.m. ET, FOX)
Opening line
- Commanders +3.5
- Over/Under 46.5
- View full Eagles vs. Commanders odds and matchup
- Read our Eagles vs. Commanders picks and predictions (coming soon)
A big NFC East matchup has the Eagles opened as short as -3.5 on the road at Washington. Philadelphia got a scare with WR A.J. Brown but it appears his ankle is OK. Quarterback Jalen Hurts is playing through a broken finger on his non-throwing hand. This spread is up to Philly -4 at some shops on Sunday night. The total opened at 46.5 points. The early forecast for Hyattsville sees wind gusts flirting with 40 mph and temperatures “feeling like” 21 degrees.
Cardinals vs Panthers odds (Sunday, 1:00 p.m. ET, FOX)
Opening line
- Panthers +4.5
- Over/Under 45.5
- View full Cardinals vs. Panthers odds and matchup
- Read our Cardinals vs. Panthers picks and predictions (coming soon)
Carolina opened as big as a 4.5-point home underdog to Arizona in Week 16. The Over/Under hit the board at 45.5 points and climbed to 46.5 O/U on Sunday night. Even Charlotte can’t avoid this cold snap on Sunday, with wind gusts up to 30 mph making it “feel like” 33 degrees on the field.
Vikings vs Seahawks odds (Sunday, 4:05 p.m. ET, FOX)
Opening line
- Seahawks +2.5
- Over/Under 45.5
- View full Vikings vs. Seahawks odds and matchup
- Read our Vikings vs. Seahawks picks and predictions (coming soon)
Opening line analysis coming soon!
Jaguars vs Raiders odds (Sunday, 4:25 p.m. ET, CBS)
Opening line
- Raiders -1.5
- Over/Under 39.5
- View full Jaguars vs. Raiders odds and matchup
- Read our Jaguars vs. Raiders picks and predictions (coming soon)
Opening line analysis coming soon!
49ers vs Dolphins odds (Sunday, 4:25 p.m. ET, CBS)
Opening line
- Dolphins -2.5
- Over/Under 46.5
- View full 49ers vs. Dolphins odds and matchup
- Read our 49ers vs. Dolphins picks and predictions (coming soon)
Mike McDaniel goes head-to-head with his mentor Kyle Shanahan in this non-conference clash. Miami needs a win to stay alive in the AFC playoff hunt while the 49ers do enjoy a mini-bye after last Thursday's loss. The Dolphins opened as 2.5-point home favorites with the total hitting the board at 46.5 points. Miami WR Jaylen Waddle is questionable after a knee injury on Sunday.
Buccaneers vs Cowboys odds (Sunday, 8:20 p.m. ET, NBC)
Opening line
- Cowboys +4.5
- Over/Under 48.5
- View full Buccaneers vs. Cowboys odds and matchup
- Read our Buccaneers vs. Cowboys picks and predictions (coming soon)
Sunday Night Football sends Tampa Bay to Dallas, with the Cowboys opening as high as +4.5 and drawing early action. Dallas is as short as +3.5 on Sunday night. This total opened at 48.5 points but has dropped to 47.5 points with early play on the Under.
Also see: full Sunday Night Football odds
Saints vs Packers odds (Monday, 8:15 p.m. ET, ESPN/ABC)
Opening line
- Packers -12.5
- Over/Under 42.5
- View full Saints vs. Packers odds and matchup
- Read our Saints vs. Packers picks and predictions (coming soon)
Opening line analysis coming soon!
Also see: full Monday Night Football odds
Best NFL bets this week
Looking for our favorite spread, total, and NFL prop bets for this week's action? Check out our best free NFL picks from the Covers staff!
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