Bought Moderna on April 3 for a little over 30 bucks. $46 today. I'm pleased but am unsure of when to get out. Not now for sure, but soon. I hope they come up with the vaccine for everyone's sake.
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Bought Moderna on April 3 for a little over 30 bucks. $46 today. I'm pleased but am unsure of when to get out. Not now for sure, but soon. I hope they come up with the vaccine for everyone's sake.
Moderna has started dosing the first participants in all age cohorts of the Phase II clinical trial of its Covid-19 vaccine candidate, mRNA-1273.
mRNA-1273 is an mRNA vaccine encoding for a prefusion stabilised form of the Spike (S) protein, which was chosen by the company in alliance with Vaccine Research Center (VRC) at the National Institute of Allergy and Infectious Diseases (NIAID).
The Phase II trial will assess the safety, reactogenicity and immunogenicity of two vaccinations of mRNA-1273 administered 28 days apart. It is set to involve 600 healthy participants across the age groups of 18-55 and 55 and above.
Participants will receive either a 50µg dose, a 100µg dose, or placebo at both vaccinations and will be followed for 12 months after the second vaccination.
In the Phase I trial of the vaccine candidate, 25µg and 100µg dose levels demonstrated neutralising antibody titers at or above convalescent sera and were observed to be generally well-tolerated.
Moderna has decided to drop the assessment of the 250µg dose in the Phase II trial.
The US Food and Drug Administration (FDA) completed a review of the company’s investigational new drug (IND) application for the vaccine candidate on 6 May and granted fast track designation on 12 May.
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Moderna has started dosing the first participants in all age cohorts of the Phase II clinical trial of its Covid-19 vaccine candidate, mRNA-1273.
mRNA-1273 is an mRNA vaccine encoding for a prefusion stabilised form of the Spike (S) protein, which was chosen by the company in alliance with Vaccine Research Center (VRC) at the National Institute of Allergy and Infectious Diseases (NIAID).
The Phase II trial will assess the safety, reactogenicity and immunogenicity of two vaccinations of mRNA-1273 administered 28 days apart. It is set to involve 600 healthy participants across the age groups of 18-55 and 55 and above.
Participants will receive either a 50µg dose, a 100µg dose, or placebo at both vaccinations and will be followed for 12 months after the second vaccination.
In the Phase I trial of the vaccine candidate, 25µg and 100µg dose levels demonstrated neutralising antibody titers at or above convalescent sera and were observed to be generally well-tolerated.
Moderna has decided to drop the assessment of the 250µg dose in the Phase II trial.
The US Food and Drug Administration (FDA) completed a review of the company’s investigational new drug (IND) application for the vaccine candidate on 6 May and granted fast track designation on 12 May.
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