I just got back from 5 days there.
How many guys are going? Where are you staying?
We had 5 guys and if you want to go to a club I would advise you get bottle service. Its the best way to get right in and it may seem like a lot at first but not when regular drinks are 17 a pop. I know at Jet we got 2 bottles for 525 and at Tao we got one bottle for 700 with all the mixers including red bull. Tao is the "in" club there right now its in the Venetian. For after hours, go to Drai's at Bills right on the strip.
If you go to Tao, you must like Asian women. There are a lot of them and most are hot. Tao is probably the best club i have ever been to but there could be a few more American beauties there if you ask me. Body English at Hard Rock is nice for that.
Tattoos go to the Palms for their famous parlor and then do yourself a favor and stop by the mexican restaraunt there and get something to eat, best Mexican in Vegas.
I had more fun at the pool then anywhere else. The Mirage has bare, which has topless there and was better then a lot of people had suggested. If you like partying with pornstars, hookers, strippers and hot chicks. Ditch Fridays at the Palms is wonderful, go there, trust me.
We were approached twice for drugs. My days of drug abuse are over but it seemed easy at Planet Hollywood and if you chose to take a walk in front of Fatburger area on the strip you will score it easily.
Hookers are all around, a couple of my buddies got rub and tugs by the Orleans at an asian spa, but said they would have rather just paid the extra couple hundo for a hot hooker. They are on cell phones all over the casinos at night, if you cant tell who they are you need your head examined.
Betting sports go to the Bellagio or Hilton. I recommend Bellagio because they are generous with the drink tix. We stayed at Mirage and they seemed to hold the drink tix hostage. We did get messed up a couple of nites for predrinking in the Mirage book but they dont have enough servers so it will take some time especially if its busy and you have to show the asswipes at the counter your horse tix. We found some losing tickets laying around on tables and took them up and we were fine.
On the strip in front of O'sheas, where they have beer pong tables, which is across from Caesars there will be a guy who will offer you a round of drinks, free limo, and free entry into a strip club if you want. We were tempted but went to Tao instead. Not a bad option to have.