Browns @ Ravens (-17.5)
Ravens are currently in the driver's seat to win the AFC North. The only way they can lose hold of the lead is if they lose to the Browns and the Steelers beat the Bengals. I could see the latter possibly happening, but I doubt the Ravens lose this game. Whether they cover the large chalk is another question. Either way, the Ravens should end the season as the champs of their division.
Bengals (-1.5) @ Steelers
Basically what I wrote above applies to the Steelers. They need to beat the Bengals, but also hope the Browns pull off a win against the Ravens. Now the Bengals have an outside shot here to make the playoffs. Not only do they need to beat the Bengals, but they have to rely on the Broncos losing to (possibly) the Chiefs backups and also need the Dolphins to lose to the Jets. I can see the latter happening (warm weather team flying into New Jersey to play in the cold). It's a good thing that this game is on earlier in the day. The Bengals will have to play like the Chiefs will win to get their motivation up.
Saints @ Buccaneers (-13.5)
The Buccs have taken over the NFC South lead. Because they lost both games to the Falcons, they'll have to finish the season with a better record than the Falcons. With a 1 game lead, all they have to do is win, or see the Falcons lose. With the Falcons playing the Panthers, the Buccs should simply look to take care of business. Division games are always tough to cap this late into the season, because intra-division teams hate each other. But the Saints could be looking for a sweeter draft slot, and the Buccs need to end the season in a resounding high note.
Giants @ Eagles (-3)
Hurts may still be hurt. No need to play him this last week with #2 seed all locked up for the Eagles. I'm not sure what the status on Pickett is. The bigger question is will Saquon play to amass the 101 years needed to break Eric Dickerson's rushing record. (Dickerson rushed for 2,105 y rds. There will be an asterisk next to the record regardless since Dickerson set that in a 16-game season.