Diamondbacks vs Padres Prediction, Picks, and Odds for Tonight’s MLB Game

It may only be June but there's a pivotal series happening in the NL West between Arizona and San Diego. With the teams separated by just three games, this four-game set could play a huge roll down the line. Who will take the opener? Our MLB expert says to side with the visitors.

Kenny Ducey - Betting Analyst at Covers
Kenny Ducey • Betting Analyst
Jun 6, 2024 • 14:24 ET • 4 min read
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This article contains predictions for an old game!

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Ketel Marte Arizona Diamondbacks MLB
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The Arizona Diamondbacks and San Diego Padres are two teams trending in opposite directions at the moment and when this four-game series is said and done it might be the Diamondbacks who jump two spots in the National League West standings to overtake the Padres in second place.

Coming off of four straight losses, San Diego will roll the dice with Randy Vasquez, who’s filling in for a severely injured starting rotation, against the struggling Slade Cecconi who will be hoping to deliver the visitors a fifth win in six games.

Who gets the better of this one in our Diamondbacks vs Padres predictions? Let's dive right into our MLB picks for Thursday, June 6. 

Diamondbacks vs Padres prediction

My best bet
Diamondbacks moneyline (+107 at BetRivers)

My analysis
There might be some redeeming qualities to Slade Cecconi despite a pretty poor start to his big-league career. He’s made 10 starts and 14 total appearances, posting a 5.06 ERA across 64 frames, but this season he’s found a way to pitch to contact at a much better rate than in his first taste of the majors.

Cecconi’s embraced being a fly ball-oriented pitcher, using the pitcher-friendly Chase Field to his benefit and posting a .220 Expected Batting Average through seven outings with some continued excellence in the walk department. He’s brought his hard-hit rate down to right around the league average after sitting 11 points higher than the norm last year, and while there have been some barrels that have led to a high Expected Slugging it’s not going to hurt you too much in Arizona, or in San Diego as it were given its below-average Park Factor for homers over the years.

Randy Vasquez, meanwhile, has profiled somewhat similarly with a stellar walk rate and few hard-hit balls as a contact-oriented pitcher. He’s opted for more ground balls than his counterpart, but it’s really been line drives that he’s given up more than most – and that’s why he owns one of the worst xBA marks around at .316.

The thing here is that the Padres have begun to trend back down in wRC+ over the last week or so, and the Diamondbacks are just outside the bottom third of the league in that category over the last 14 days. Its biggest issue has been strikeouts, while San Diego has lacked any power to speak of. Yes, the Padres are hitting an acceptable .247 against ground-ballers this year, but their slugging, as you might expect in that matchup, has lagged behind, and with no power this team can only hurt you so much.

I trust Cecconi to pitch to contact a lot better than Vasquez despite the fact that it’s been the Padres who have technically displayed more at the plate lately, and on the flip side a meeting with a pitcher in Vasquez who has trouble racking up strikeouts should be what Arizona needs to stay hot and make a move in the division.

Diamondbacks vs Padres same-game parlay (SGP)

Diamondbacks moneyline

Ketel Marte 2+ total bases

Jurickson Profar to record a hit

It’s hard to get any pitching props into this one given strikeouts will be at a premium and it’s anyone’s guess how long two struggling starters stick around in this one, so I’ll turn to one hitter per team to boost the odds of this one a bit.

Starting on the Arizona side of things, Ketel Marte has turned into someone we can really trust to bring his bat to each and every game and has the benefit of hitting high in the order to give us a whole host of chances at success here. He’s ranked third among all hitters in total bases versus finesse pitchers, hitting .348 in the split, and should have a wonderful time hitting against Vasquez with his inability to successfully get outs on contact.

Then I’ll opt for Jurickson Profar who, while not quite as hot as Marte, has hit .323 this season and has four hits in his last four games. He’s sporting a .286 average against fly-ball pitchers and has been a hit machine since the middle of May with a .321 average over his last 24 contests.

Learn how to bet a same-game parlay with these helpful tips and strategies.

Diamondbacks vs Padres odds

Diamondbacks vs Padres live odds

Diamondbacks vs Padres opening odds

  • Run line: Arizona +1.5 (-190) | San Diego -1.5 (+155)
  • Moneyline: Arizona +107 | San Diego -116
  • Over/Under: Over 8.5 | Under 8.5

Diamondbacks vs Padres spread and Over/Under analysis

  • The Diamondbacks opened up close to +110 on the moneyline and have seen some steady action as the day has worn on Thursday, moving close to even money to win.
  • The total sits at its opening number of 8.5, and despite a very brief move down to eight runs, the movement has been slightly towards the Over with a marginal increase in price.
  • According to DraftKings, 40% of the bets and 44% of the moneyline handle is on the Diamondbacks.
  • The Over has been a favorite of bettors, commanding 69% of the tickets on the total and a firm 81% of the cash.

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Diamondbacks vs Padres trend

The Arizona Diamondbacks have hit the 1st Five Innings (F5) Team Total Over in 9 of their last 11 away games (+6.65 Units / 46% ROI). Find more MLB betting trends for Diamondbacks vs. Padres

Diamondbacks vs Padres game info

Location: Petco Park, San Diego, CA
Date: Thursday, 6-6-2024
First pitch: 9:40 p.m. ET
TV: ARID, SDPA
Diamondbacks starting pitcher: Slade Cecconi
(1-4, 5.60 ERA)
Padres starting pitcher: Randy Vasquez
(1-3, 5.74 ERA)

Diamondbacks vs Padres latest injuries

Diamondbacks vs Padres weather

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Kenny Ducey - Covers
Betting Analyst

Kenny Ducey has worked in sports media for more than 10 years and began his journey as a credentialed reporter with Fordham University's WFUV Sports before moving on to Sports Illustrated. There, he wrote about baseball, basketball, and tennis - twice covering the NBA Finals.

He's been in the betting space for seven years, and has established himself as a top expert in MLB and tennis handicapping with brands like Tennis Channel, NBC Sports, and DraftKings. He's also been a frequent guest on betting shows such as MLB's Bettor's Eye and Tennis Bets Live.

Kenny has a knack for identifying underappreciated pitchers and tennis players as moneyline underdogs and credits his unique data analysis and hours of watching sports as the biggest reasons for success through the years. His best advice to bettors? Watch the games, trust your eye, and always question the public narrative.

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