Red Sox vs Rays Prediction, Picks & Odds for Today’s MLB Game

The Rays scored 16 runs yesterday, and our MLB picks expect those bats to stay hot against Walker Buehler tonight.

Tom Oldfield - Betting Analyst at Covers.com
Tom Oldfield • Betting Analyst
Apr 15, 2025 • 11:42 ET • 4 min read
Information icon

This article contains predictions for an old game!

Latest MLB Picks
Yandy Diaz Tampa Bay Rays MLB
Photo By - Imagn Images. Tampa Bay Rays slugger Yandy Diaz.

The Tampa Bay Rays are settling into their new temporary home, and they’ll look to continue their offensive onslaught tonight against the Boston Red Sox.

Tampa Bay jumped all over Tanner Houck last night on the way to a 16-1 win, improving to 8-5 at George M. Steinbrenner Field, and my Red Sox vs. Rays predictions expect the bats to show up again here to crank up the heat on a Boston team that’s slipped to 8-10.

Take a closer look at this April 15 clash with my MLB picks and betting angles.

Red Sox vs Rays prediction

My Red Sox vs Rays best bet: Rays team total Over 4.5 (-105 at Caesars)

The Tampa Bay Rays faced some nail-biters last week, with a pair of one-run ball games against the Angels, but it was a very different story yesterday as their hitters tucked into what amounted to batting practice in their series opener against the Boston Red Sox, surging into a 14-1 lead through three innings.

The Rays now rank third in the majors in batting average, and I’m wagering on their offense to get after Walker Buehler in tonight’s rematch and cash the Over on a 4.5-run team total.

This might sound like an overreaction to the fireworks last night, but while that power surge isn’t sustainable, it’s not as if the Rays had been struggling to put runs on the board before that. 

They scored 18 runs in the weekend series against the Braves, and nine Tampa Bay players have already logged double-digit hits this year, led by Jonathan Aranda and Junior Caminero. The Rays are averaging 5.23 runs per game at home in 2025, the eighth-best mark in the league.

Buehler rebounded from two subpar outings to quieten the Blue Jays on Thursday, but there will be an adjustment to pitching at the unfamiliar George M. Steinbrenner Field.

Though Brandon Lowe is the only Tampa Bay hitter who’s gone head-to-head with Buehler previously, I trust the hosts’ deep lineup to figure him out, and they got an extra spark yesterday with Kameron Misner crushing a pair of dingers from the No. 6 spot.

The Rays have scored 5+ runs in four of their past six home contests, and this is a nice price for another productive day at the plate.

Red Sox vs Rays same-game parlay (SGP)

Rays team total Over 4.5

Yandy Diaz Over 1.5 total bases

Ryan Pepiot Under 6.5 strikeouts

First baseman Yandy Diaz stands out among the hot Tampa Bay bats. After an underwhelming first few weeks by his high standards, he’s piled up nine hits in his last six games, including a second straight lead-off homer last night.

I’m taking the Over on 1.5 total bases for my SGP, with Diaz dragging his average up to .241 at home this year and hitting .321 over the past week. That bodes well as he battles Buehler, who gave up a .282 batting average against right-handed batters in 2024.

I’m also fading Ryan Pepiot's strikeout prop, despite his 3.38 ERA and 16 strikeouts through three starts. He finished with eight Ks in his season debut but only added another eight combined across his last two outings. Despite managing a measly seven runs in their past four games, the Red Sox have dangerous hitters at the top of the order, and Pepiot has lasted more than five innings in just one of his last five appearances on the mound.

A line of 6.5 strikeouts feels too high for the fourth-year righty, who could hand things over to the bullpen before going through the Boston order a third time.

Learn how to bet a same-game parlay with these helpful tips and strategies.

Red Sox vs Rays odds

Red Sox vs Rays live odds

Red Sox vs Rays opening odds

  • Moneyline: Boston +105 | Tampa Bay -135
  • Run line: Boston +1.5 (-185) | Tampa Bay -1.5 (+155)
  • Over/Under: Over 9 | Under 9

Red Sox vs Rays trend

The Red Sox have cashed their team total Under in 11 of their last 15 road games. Find more MLB betting trends for Red Sox vs. Rays.

How to watch Red Sox vs Rays and game info

Location George M. Steinbrenner Field, Tampa, FL
Date Tuesday, 4-15-2025
First pitch 7:05 p.m. ET
TV NESN, FDSN-Sun
Red Sox starting pitcher Walker Buehler
(1-1, 5.74 ERA)
Rays starting pitcher Ryan Pepiot
(1-1, 3.38 ERA)

Red Sox vs Rays latest injuries

Red Sox vs Rays weather

Not intended for use in MA.
Affiliate Disclosure: Our team of experts has thoroughly researched and handpicked each product that appears on our website. We may receive compensation if you sign up through our links.

Pages related to this topic

Tom Oldfield - Covers
Betting Analyst

Tom Oldfield’s sports writing journey over the past 20 years has taken him from the Premier League and Champions League to the NFL, NBA, WNBA and MLB, with a wide range of articles and betting previews. Tom has worked closely with London’s Sportsbeat sports news agency as well as (thrillingly!) covering the Toronto Raptors’ 2019 NBA championship run, and he has appeared on BBC World Service and The Back Page podcast.

A graduate of the University of Nottingham in the UK, he is the author of biographies on Cristiano Ronaldo, Rafael Nadal, Gary Neville and Cesc Fabregas, and he co-authors a long-running series of children’s soccer books with his brother, Matt.

As a regular bettor across the top sports leagues, particularly with FanDuel and bet365, he is well versed on all the major markets and the next big game is rarely far from his thoughts. The best betting advice he has received is to monitor multiple sportsbooks to grab the best possible value.

Popular Content

Covers is verified safe by: Evalon Logo GPWA Logo GDPR Logo GeoTrust Logo Evalon Logo