The Oklahoma Sooners were able to stay perfect with a dramatic comeback victory over the Texas Longhorns in the Red River Showdown last week. Now, Lincoln Riley’s team takes on the TCU Horned Frogs at Memorial Stadium in Norman, Oklahoma at 7:30 p.m. ET on Saturday, October 16.
Will the Horned Frogs find a way to upset the Sooners? Keep reading our TCU vs. Oklahoma picks and predictions to find out.
TCU vs Oklahoma odds
Odds via the Covers Line, an average comprised of odds from multiple sportsbooks.
Oklahoma was a 12.5-point favorite over TCU at open, but the Horned Frogs are now getting 13.5 in this one. The action seems pretty split as far as tickets go, so it could mean that sharps are betting on the Sooners. The total opened at 65.5 in this game and has since moved to anywhere between 63.0 and 64.0.
Use the live odds widget above to track any future line movements right up until kickoff and be sure to check out the full college football odds before placing your bets.
TCU vs Oklahoma picks
Picks made on 10/15/2021 at 3:00 p.m. ET.
Click on each pick to jump to the full analysis.
If you're signing up for a new sportsbook for the 2021 college football season, here are two of the best welcome bonuses available:
USA: Risk-free bet up to $5,000 at Caesars. Claim Now
Canada: Get up to $500 in free bets at Sports Interaction. Claim Now
TCU vs Oklahoma game info
• Location: Memorial Stadium, Norman, OK
• Date: Saturday, October 16, 2021
• Time: 7:30 p.m. ET
• TV: ABC
TCU vs Oklahoma betting preview
Weather
Be sure to monitor the gametime conditions with our NCAA football weather info.
Key injuries
TCU: Max Duggan QB (Questionable), Carter Ware TE (Questionable), Wyatt Harris DE (Questionable), Corey Bethley DL (Questionable), Bud Clark S (Out), John Lanz OL (Questionable), Wes Harris OL (Questionable), Zach Evans RB (Questionable), JD Spielman WR (Questionable), Quentin Johnston WR (Questionable), Khari Coleman DE (Questionable), Mikel Barkley WR (Out).
Oklahoma: Kendall Dennis DB (Questionable), Nathan Rawlins-Kibonge DE (Questionable), Delarrin Turner-Yell S (Questionable), Jeremiah Criddell S (Questionable), Isaiah Coe DL (Questionable), Cody Jackson WR (Questionable), Woodi Washington DB (Out), Jalen Redmond DE (Out), Theo Wease WR (Out).
Find our latest NCAA football injury reports.
Betting trend to know
Oklahoma is 9-3 against the spread in its last 12 games against teams with winning road records. Find more NCAA betting trends for TCU vs. Oklahoma.
TCU vs Oklahoma predictions
Oklahoma -13.5 (-105)
Quarterback Max Duggan and running back Zach Evans are both questionable coming into this meeting with Oklahoma, which just isn’t a great sign of things to come for the Horned Frogs. Even if those two are able to go in this one, they’ll be playing at less than 100 percent health. That’s not going to cut it against a Sooners team that seemed to find a whole other gear in the second half of last week’s win over the Longhorns.
Lincoln Riley replaced quarterback Spencer Rattler — the favorite to win the Heisman Trophy before the season — with Caleb Williams at halftime of the Red River Showdown. From there, the Sooners' offense looked like a typical explosive Riley attack. Oklahoma was scoring at will and it energized the team’s defense as well. Now, it appears Williams will get the nod as the starting quarterback in this game, and it should be a good thing for this Oklahoma offense. Rattler is arguably a better pure passer than Williams is, but he doesn’t have the same mobility or creativity. Those are the same traits that made Kyler Murray and Jalen Hurts so special in this offense.
On the TCU side, this defense isn’t the dominant unit it has been under head coach Gary Patterson in the past. The Horned Frogs have allowed at least 31 points in each of their last four games, and they haven’t been particularly effective at stopping either the pass or the run. Against a team that is capable of mixing it up extremely well, it’s hard to envision TCU getting enough stops to keep this one close.
Last year, the Sooners beat the Horned Frogs 33-14 as 7-point road favorites. Oklahoma has now won seven games in a row in this series, and the team has covered in five of those games.
Under 64.0 (-105)
The Under has hit in four of the last five meetings between these teams, with the average number of points scored in those contests being 58.8 points per game. However, that average is driven way up by a 52-27 win by the Sooners back in 2018 — the lone game to go Over in that span. This year’s contest should resemble something like last year’s game.
Whether or not Duggan is out there, the Sooners defense is capable of limiting offenses that don’t make a lot of plays in the passing game. Duggan is more of a dual-threat runner that can hit open receivers, but he doesn’t beat defenses over the top very often.
As for Oklahoma, the fact that they have a quarterback under center that likes to run the ball should mean that the team’s drives will chew up more clock. Overall, it wouldn’t be too surprising if this game ended with the Sooners putting up 38 or 42 points and holding the Horned Frogs to fewer than three touchdowns.
Did you know that if you parlayed our TCU vs. Oklahoma picks, you could win $28.12 on a $10 bet?
Use our college football parlay calculator to create your own parlays and see their potential payouts.
Where can I bet on college football odds?
You can bet on college football odds at every online and casino sportsbook, including NCAA moneylines, spreads, Over/Under totals, and a ton of college football prop odds. Head over to our best football betting sites for the top spots to bet on college football odds in your area.
