NFL Odds Week 15: Lines & Spreads For Every Game

NFL odds Week 15

Matchup	Spread	Moneyline	Over/Under
Rams vs 49ers	49ers -3	Rams +125 49ers -150	48.5
Bengals vs Titans	Titans +5	Bengals -275 Titans  +200	46.5
Chiefs vs Browns	Browns +4	Chiefs -245 Browns +195	43
Ravens vs Giants	Giants +16	Ravens -1600 Giants +800	43
Cowboys vs Panthers	Panthers -3	Cowboys +125 Panthers -155	43
Jets vs Jaguars	Jaguars +3.5	Jets -185 Jaguars +150	40.5
Commanders vs Saints	Saints +7.5	Commanders -400 Saints +310	43.5
Dolphins vs Texans	Texans -3	Dolphins +125 Texans -150	47
Steelers vs Eagles	Eagles -5.5	Steelers +200 Eagles -350	43
Bills vs Lions	Lions -2.5	Bills +120 Lions -145	54.5
Colts vs Broncos	Broncos -4	Colts +165 Broncos -200	44
Patriots vs Cardinals	Cardinals -6	Patriots +200 Cardinals -250	47
Buccaneers vs Chargers	Chargers -3	Buccaneers +125 Chargers -150	45.5
Packers vs Seahawks	Seahawks +2.5	Packers -150 Seahawks +125	46
Bears vs Vikings	Vikings -7	Bears +260 Vikings -350	43.5
Falcons vs Raiders	Raiders +5.5	Falcons -250 Raiders +195	44.5

Lines as of 12-15.

There are big games all over the NFL Week 15 odds board, with none bigger than the potential Super Bowl preview between the Buffalo Bills and Detroit Lions.

Besides that colossal non-conference clash, Sunday Night Football features a key NFC showdown between the Green Bay Packers and Seattle Seahawks. We also get not one but two Monday Night Football games in Week 15, with the Chicago Bears facing the Minnesota Vikings and the Atlanta Falcons taking on the Las Vegas Raiders.

Here's a look at the NFL Week 15 odds as kickoffs draw near.

Rams vs 49ers odds (Thursday, 8:15 p.m. ET, Amazon Prime)

Opening line

• 49ers -2.5
• Over/Under 47.5
• View full Rams vs. 49ers odds and matchup
• Read our Rams vs. 49ers picks and predictions

The Rams scored a huge upset over Buffalo at home but run the risk of a letdown spot in an important NFC West war against the 49ers. San Francisco opened as a 2.5-point home favorite for the Week 15 opener with one book hitting the board at -3 — though it's back at -2.5 across most books. The total opened at 47.5 O/U and is as high as 49 on game day.

Also see: full Thursday Night Football odds

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Bengals vs Titans odds (Sunday, 1:00 p.m. ET, FOX)

Opening line

• Titans +4.5
• Over/Under 47.5
• View full Bengals vs. Titans odds and matchup
• Read our Bengals vs. Titans picks and predictions

Cincinnati is coming off a big win on Monday and opened as a 4.5-point road favorite at Tennessee in Week 15 with the spread as high as Bengals -5.5 on Sunday morning. This total hit the board at 47.5 points and it down to 46.5 O/U..

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Chiefs vs Browns odds (Sunday, 1:00 p.m. ET, CBS)

Opening line

• Browns +6.5
• Over/Under 44.5
• View full Chiefs vs. Browns odds and matchup
• Read our Chiefs vs. Browns picks and predictions

The Chiefs win again but fail to cover on SNF. Kansas City opened as a 6.5-point home chalk hosting the Browns in Week 15 before falling to KC -4 by Thursday. That spread is up to -4.5 on Sunday. This total hit the board at 44.5 O/U and has slowly dropped to 41.5 O/U.

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Ravens vs Giants odds (Sunday, 1:00 p.m. ET, CBS)

Opening line

• Giants +13.5
• Over/Under 43.5
• View full Ravens vs. Giants odds and matchup
• Read our Ravens vs. Giants picks and predictions

Baltimore is coming off the bye and ready to run toward the postseason. Standing in the Ravens’ way in Week 15 is the Giants and a massive point spread. Baltimore opened as a 13.5-point favorite and jumped to -14.5 in the hour after posting. That spread has only widened, with Ravens -17 the most common number as of Sunday. This total opened at 43.5 points, and after bumping up slightly, it's fallen to a consensus of 42.5.

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Cowboys vs Panthers odds (Sunday, 1:00 p.m. ET, FOX)

Opening line

• Panthers +1.5
• Over/Under 43.5
• View full Cowboys vs. Panthers odds and matchup
• Read our Cowboys vs. Panthers picks and predictions

Following Dallas’ home loss on Monday, Carolina opened as a 1.5-point favorite at some books while others hit the board at -1. To some surprise, the Panthers are now favored by three. The total for this game opened at 43.5 O/U and is down to 42.5 O/U.

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Jets vs Jaguars odds (Sunday, 1:00 p.m. ET, FOX)

Opening line

• Jaguars +3.5
• Over/Under 40.5
• View full Jets vs. Jaguars odds and matchup
• Read our Jets vs. Jaguars picks and predictions

The Jets hit the board as 3.5-point favorites and has returned to that number after briefly hitting a field goal. Gang Green is coming off a crushing loss in overtime at Miami and playing in Florida for the second straight week. The total opened at 40.5 and is up to 41 points at some books.

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Commanders vs Saints odds (Sunday, 1:00 p.m. ET, FOX)

Opening line

• Saints +6.5
• Over/Under 43.5
• View full Commanders vs. Saints odds and matchup
• Read our Commanders vs. Saints picks and predictions

The Commanders are coming off the bye and looking to finish their surprise season with a spot in the NFC tournament. Washington opened as a 6.5-point road favorite at New Orleans and jumped to -7.5 with Saints starting backup QB Jake Haener. This total is at 43.5 — a four-point swing from the look-ahead line of 47.5 last week.

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Dolphins vs Texans odds (Sunday, 1:00 p.m. ET, CBS)

Opening line

• Texans -2.5
• Over/Under 47.5
• View full Dolphins vs. Texans odds and matchup
• Read our Dolphins vs. Texans picks and predictions

Houston hit the board between -2 and -2.5, coming off the bye week and hosting a hot Dolphins team in an important AFC game in Week 15. The Texans are as big as -3 on Sunday morning. The Over/Under opened at 47.5 points and is down to 45.5 O/U. 

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Steelers vs Eagles odds (Sunday, 4:25 p.m. ET, FOX)

Opening line

• Eagles -4.5
• Over/Under 45.5
• View full Steelers vs. Eagles odds and matchup
• Read our Steelers vs. Eagles picks and predictions

A rare state rivalry between the Eagles and Steelers saw Philadelphia open as high as -4.5 with some books shorter at -4. Philly -5.5 is the market consensus on Sunday morning. The total opened at 45.5 points and has been bet down to 43 with a ton of play on the Under. 

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Bills vs Lions odds (Sunday, 4:25 p.m. ET, CBS)

Opening line

• Lions -3
• Over/Under 52.5
• View full Bills vs. Lions odds and matchup
• Read our Bills vs. Lions picks and predictions

The Lions play in another big game in Week 15, opening as 3-point home favorites versus the Bills. Buffalo is in bounce-back mode after laying an egg in L.A. this Sunday and that’s convinced early money to take the field goal with the underdog, slimming this spread to +2.5. The total opened at 52.5 and quickly swelled to 54.5 O/U.  

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Colts vs Broncos odds (Sunday, 4:25 p.m. ET, CBS)

Opening line

• Broncos -4.5
• Over/Under 43
• View full Colts vs. Broncos odds and matchup
• Read our Colts vs. Broncos picks and predictions

This is a vital AFC game for both teams as they fight for a wild-card ticket down the stretch. Denver opened as a 4.5-point favorite and was quickly raised to -5.5 with early money on the home side. That has since come back down to earth to as low as -3.5. The Over/Under opened at 43 points and is up to a high of 44.5 O/U.

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Patriots vs Cardinals odds (Sunday, 4:25 p.m. ET, CBS)

Opening line

• Cardinals -6.5
• Over/Under 45
• View full Patriots vs. Cardinals odds and matchup
• Read our Patriots vs. Cardinals picks and predictions

The Cardinals are mired in a three-game slide and hoping to snap that skid, opening as 6.5-point home favorites versus a well-rested Patriots team. Arizona is down to -6 on game day. This total opened at 45 points and is up to 46.5 O/U. 

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Buccaneers vs Chargers odds (Sunday, 4:25 p.m. ET, FOX)

Opening line

• Chargers -3
• Over/Under 46.5
• View full Buccaneers vs. Chargers odds and matchup
• Read our Buccaneers vs. Chargers picks and predictions

The Chargers opened between -2.5 and -3 after their slim loss to Kansas City on Sunday night. This total opened between 45.5 and 46.5 O/U. The higher total is nowhere to be seen on Sunday, with books down to 45.5 O/U.

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Packers vs Seahawks odds (Sunday, 8:20 p.m. ET, NBC)

Opening line

• Seahawks +2.5
• Over/Under 46.5
• View full Packers vs. Seahawks odds and matchup
• Read our Packers vs. Seahawks picks and predictions

The Packers enjoy a mini-bye after losing a big game last Thursday. Now, they play their second straight road game on the West Coast, laying -2.5 as a visitor after being a field goal fave earlier in the week. The Seahawks have won three in a row and need to stay afloat in the NFC West race. The total for Sunday Night Football opened at 46.5, went up to 47.5, and has come back to the opener.

Also see: full Sunday Night Football odds

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Bears vs Vikings odds (Monday, 8:00 p.m. ET, ABC)

Opening line

• Vikings -6.5
• Over/Under 42.5
• View full Bears vs. Vikings odds and matchup
• Read our Bears vs. Vikings picks and predictions

The NFC North shares the Monday night spotlight with the Bears visiting the Vikings. Minnesota opened as a 6.5-point home chalk and has been bet up to a touchdown favorite. The Over/Under number hit the board at 42.5 points and has climbed to 44.5 with early play on the Over indoors at Minnesota.

Also see: full Monday Night Football odds

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Falcons vs Raiders odds (Monday, 8:30 p.m. ET, ESPN)

Opening line

• Raiders +6.5
• Over/Under 43.5
• View full Falcons vs. Raiders odds and matchup
• Read our Falcons vs. Raiders picks and predictions

The other Monday Night Football matchup opened with the Raiders getting as many as 6.5 points from the oddsmakers, with QB Aidan O’Connell likely out and QB3 Desmond Ridder getting the call. That number slipped to -5.5, with folks having less faith in the Falcons. This total opened at 41.5 points but has jumped to 44.5 as of Sunday morning.

Also see: full Monday Night Football odds

More weekly NFL odds content

• Week 1 odds
• Week 2 odds
• Week 3 odds
• Week 4 odds
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