Chicago @ New York preview

Last Meeting ( May 13, 2016 ) Chi. White Sox 7, NY Yankees 1

After shutting down the New York Yankees with one star left-hander, the Chicago White Sox will attempt to do it with another when they send Jose Quintana to the mound Saturday in the Bronx. Quintana enters leading the American League in ERA (1.38) -- just a shade better than teammate Chris Sale, who did his part to give the White Sox the win in the series opener Friday.

Sale scattered six hits and struck out six in a complete game 7-1 victory, lowering his ERA to 1.67 with a tidy 99-pitch effort. The win ended a two-game losing streak for first-place Chicago and gave the club just its second victory in the last 13 games at Yankee Stadium. New York will be hoping for some positive news on right-hander Luis Severino, who was pounded for all seven runs Friday night before departing with elbow soreness. The only positive on the night for the Yankees was the second homer in as many games for third baseman Chase Headley, who has put together a modest five-game hitting streak (6-for-17) and driven in at least one run in four straight games to help offset a miserable start at the plate.

TV: 1:05 p.m. ET, CSN Chicago, YES (New York)

PITCHING MATCHUP: White Sox LH Jose Quintana (5-1, 1.38 ERA) vs. Yankees RH Ivan Nova (1-1, 4.34)

Quintana has been victorious in four consecutive starts while allowing just two runs in 28 innings. He followed up an eight-inning effort against Boston with seven stellar frames against Minnesota on Sunday and has finished at least six in six consecutive outings. The 27-year-old from Colombia has a 5.27 ERA in three career starts versus the Yankees but New York's starting lineup Friday night is a combined 3-for-31 against him.

Nova stepped into the rotation after CC Sabathia was placed on the disabled list and gave a solid performance in his first start Monday against Kansas City. The 29-year-old limited the Royals to a run in 4 2/3 innings, which left his ERA at home this year at 0.75. Nova has allowed one run in five of his six career starts against Chicago but will be wary of outfielders Austin Jackson and Melky Cabrera, who are a combined 15-for-26 versus the righty.

WALK-OFFS

1. White Sox RF Adam Eaton had three hits in the series opener and owns six multi-hit games since May 3.

2. Yankees CF Jacoby Ellsbury (hip) has missed seven straight games.

3. Chicago is averaging 6.5 runs over its last 11 road games and has an MLB-high 14 wins away from home.

PREDICTION: White Sox 5, Yankees 2