San Francisco @ Colorado preview

Last Meeting ( Apr 10, 2013 ) Colorado 0, San Francisco 10

The San Francisco Giants will feel right at home when they visit the Colorado Rockies for a four-game series beginning Thursday. San Francisco has won 11 of its last 13 games at Coors Field - outscoring Colorado 111-65 during that span - and nine straight overall against the Rockies. The Giants outscored Colorado 23-8 in a three-game sweep in San Francisco last month. The Giants began their six-game road trip by allowing 21 runs while being swept in a two-game series in Toronto.

San Francisco's Matt Cain - Thursday's starter - did not make the trip to Toronto seeing as he would have flown into Denver on Wednesday ahead of his start anyway. Cain will oppose Jhoulys Chacin, who lost his last two starts. Colorado has dropped each of its last four series 2-1 following a 6-3 setback to the Cubs in Chicago on Wednesday. The Rockies are struggling offensively with 42 runs during those 12 games - 28 in the four wins - and were nearly no-hit twice.

TV: 8:40 p.m. ET, MLB Network, Comcast SportsNet Bay Area (San Francisco), ROOT Sports (Colorado)

PITCHING MATCHUP: Giants RH Matt Cain (2-2, 5.04 ERA) vs. Rockies RH Jhoulys Chacin (3-2, 2.70)

Cain has won his last two starts while yielding three runs in 15 1/3 innings and compiling a 1.76 ERA. The 28-year-old Dothan, Ala., native posted a 6.49 ERA over six starts in April. The Giants have won his last three starts after losing the first five. Cain is 15-7 with a 3.11 ERA and a 1.19 WHIP in 28 starts against Colorado, including 5-3, 4.11, 1.31 at Coors Field. Troy Tulowitzki has feasted on Cain (18-for-53, four homers) while Carlos Gonzalez has not (4-for-34, 10 strikeouts).

Chacin allowed two runs in five innings Saturday when the Rockies were nearly no-hit for the second straight game in a 3-0 loss at St. Louis. It was the fifth time in six starts the 25-year-old Venezuelan has yielded two or fewer runs. Chacin is 3-4 with a 3.59 ERA in 10 appearances (nine starts) against the Giants, including 0-3 in his last four starts. Buster Posey is 4-for-7 with a pair of walks against Chacin while Pablo Sandoval is 7-for-17 with two homers.

WALK-OFFS

1. San Francisco leads the National League West by a half-game over Arizona and two over Colorado.

2. The Rockies have not won back-to-back games since an eight-game winning streak April 12-20.

3. Giants manager Bruce Bochy said there's a good chance Posey will catch all four games in the series. He served as the designated hitter Wednesday.

PREDICTION: Giants 9, Rockies 2