Toronto @ San Diego preview

Last Meeting ( Jun 16, 2010 ) Toronto 7, San Diego 1

Jose Bautista looks to wrap up a hot month with the bat in style when the Toronto Blue Jays open a three-game road series against the San Diego Padres on Friday. Bautista is batting .361 in May and has reached base an American League-leading 58 times to raise his season average to .291. Bautista typically struggles against the Padres. He has a .190 career average in 63 at-bats against San Diego, including a .163 mark at Petco Park.

San Diego's Jedd Gyorko has six homers in May to tie the franchise record for most blasts in single month by a rookie. The mark also is shared by Nate Colbert (September 1969), Benito Santiago (August 1987) and current outfielder Will Venable (August 2009). The Padres have lost six of nine games after falling to Seattle on Thursday. The Blue Jays were hammered by Atlanta on Thursday, giving them a split of the four games between the teams this week. Toronto's Melky Cabrera is batting .333 with 10 multi-hit games in May.

TV: 10:10 p.m. ET, RSN (Toronto), FSN (San Diego)

PITCHING MATCHUP: Blue Jays RH Chad Jenkins (1-0, 3.60 ERA) vs. Padres RH Jason Marquis (6-2, 3.70)

Jenkins is making his third start of the season and the sixth of his career. He settled for a no-decision against the Baltimore Orioles on May 26, when he gave up two runs and eight hits in five innings. Jenkins, who was the 20th overall pick in the 2009 draft, defeated the Boston Red Sox on May 12 in his other outing this campaign.

Marquis has won five consecutive decisions. He did not figure in the decision in his last outing after giving up four runs and seven hits in 3 1/3 innings against the Arizona Diamondbacks. Marquis has walked four or more batters in seven of his 10 starts. He is 1-2 with a 5.82 ERA in five career appearances (three starts) against Toronto.

WALK-OFFS

1. Toronto is 4-2 all-time against San Diego.

2. The Padres allowed five homers in Thursday’s loss to Seattle, matching the most they have surrendered since moving into Petco Park in 2004.

3. Blue Jays 3B Edwin Encarnacion is 9-for-18 with two homers against Marquis.

PREDICTION: Padres 9, Blue Jays 8