Philadelphia @ New York preview

Last Meeting ( Jul 9, 2018 ) Philadelphia 3, NY Mets 1

A pair of pitchers making their major-league debuts will square off Tuesday in New York as the hometown Mets continue a four-game series with the Philadelphia Phillies. Enyel De Los Santos, who will pitch for Team World in the upcoming MLB All-Star Futures Game, is being called up to make his debut for the Phillies opposite fellow newcomer Drew Gagnon for the Mets.

Their arrivals come on the heels of Monday's doubleheader split between the two teams, capped by Philadelphia's 3-1 victory in the second game. Aaron Nola struck out 10 and yielded one hit over seven scoreless innings while delivering all the offense he would need with a three-run double in the fifth inning for the Phillies. Wilmer Flores lifted the Mets to a 4-3 win in the opener with a pinch-hit solo blast in the bottom of the 10th and had an RBI double for his team's only run in the nightcap. New York is 42-21 against its National League East rivals since the start of 2015, including 4-2 this year.

TV: 7:10 p.m. ET, MLB Network, NBCS Philadelphia, SNY (New York)

PITCHING MATCHUP: Phillies RH Enyel De Los Santos (NR) vs. Mets RH Drew Gagnon (NR)

De Los Santos entered Monday tied for the International League lead with nine wins and was first among full-time starters in ERA. He has allowed two runs or fewer in each of his last six outings for Triple-A Lehigh Valley. The 22-year-old from the Dominican Republic was acquired last offseason in the trade that sent Freddy Galvis to San Diego.

Gagnon has made 198 appearances (138 starts) in eight seasons in the minors, including 17 this year with Triple-A Las Vegas, where he was 1-4 with a 4.67 ERA. The Long Beach State product broke in with Milwaukee in 2011 and spent 2017 with Triple-A Salt Lake in the Los Angeles Angels' organization. Gagnon is 5-17 with a 5.86 ERA in his career at the Triple-A level.

WALK-OFFS

1. The Mets placed 3B Todd Frazier (rib cage) on the 10-day disabled list and optioned RHP Chris Flexen to Triple-A Las Vegas amid a flurry of roster moves.

2. Flores' game-winning homer gave him 10 career walk-off RBI, breaking a tie with David Wright for the most in team history.

3. The Phillies optioned LHP Hoby Milner from Lehigh Valley.

PREDICTION: Phillies 6, Mets 3