San Diego @ San Francisco preview

Last Meeting ( Sep 19, 2018 ) San Francisco 4, San Diego 8

The San Francisco Giants complete a disappointing month - and season - with a six-game homestand that begins with the first of three contests against the National League West-rival San Diego Padres on Monday. The Giants have dropped four straight after Sunday’s 9-2 setback at St. Louis and managed just four victories in 20 games during September, scoring a major league-low 55 runs in that stretch.

Brandon Crawford provided the only offense on Sunday with a two-run homer for San Francisco, which has permitted 27 runs during its losing streak but owns a 41-34 record at home this season. Derek Holland has not lost since July 10 and will take the mound for the Giants in the series opener against Bryan Mitchell, who came to San Diego from the New York Yankees in an offseason trade. The Padres have optimism for the future with a stable of promising young players but will finish in last place for the second time in three years and miss the playoffs for the 12th straight season. San Diego is 8-11 in September after suffering a 14-0 loss to the Los Angeles Dodgers on Sunday, but 23-year-old right fielder Franmil Reyes is batting .328 with 10 RBIs this month despite going 0-for-8 in his last two games.

TV: 10:15 p.m. ET, FS San Diego, NBCS Bay Area (San Francisco)

PITCHING MATCHUP: Padres RH Bryan Mitchell (1-4, 6.16 ERA) vs. LH Derek Holland (7-8, 3.57)

Mitchell began the month with two strong performances before giving up four runs and nine hits - two homers - in five innings last Monday in a loss to the Giants. The 27-year-old native of North Carolina allowed two runs on six hits and five walks over 11 frames in his first two starts of September. Crawford is 3-for-4 with a homer against Mitchell, who is 1-0 with a 3.96 ERA on the road as opposed to 0-4 with a 7.55 mark at home.

Holland is unbeaten in his last 13 turns and escaped with a no-decision against San Diego on Tuesday despite permitting four runs in five innings. The 31-year-old from Ohio had strung together four straight quality starts before that outing, recording one victory while yielding five runs over 24 1/3 frames. Eric Hosmer is 9-for-24 with two doubles and a homer versus Holland, who is 1-1 with a 6.39 ERA lifetime against the Padres.

WALK-OFFS

1. San Diego OF-3B Wil Myers is 6-for-16 with two doubles, a homer and four RBIs during his four-game hitting streak.

2. San Francisco 1B-C Aramis Garcia has gone 14-for-41 with three homers and seven RBIs in 14 contests during his first stint in the major leagues.

3. The Giants already have clinched the season series, winning 10 of the 16 meetings - including five of seven at home.

PREDICTION: Giants 5, Padres 4