New York @ Denver preview

Last Meeting ( Sep 15, 2013 ) Denver 41, N.Y. Giants 23

The season is turning into a massive sinkhole for the New York Giants, dragging down their playoff chances while swallowing up their best players due to injury. One of three winless teams in the league, the Giants will travel to one of the NFL's most difficult venues when they visit the Denver Broncos on Sunday night.

New York has lost its last three games by a combined 10 points but Sunday's 22-17 loss to the Los Angeles Chargers was by far the most damaging, with starting wide receivers Odell Beckham Jr. and Brandon Marshall suffering season-ending ankle injuries. “We have to move on,” said quarterback Eli Manning. “Obviously, whenever you lose players, you have to make adjustments and other guys have to step up. Nothing has changed in that fact." Denver, on the other hand, is rested and refreshed following its bye but cannot afford a letdown as it tries to keep pace with undefeated Kansas City in the AFC West. "We're in a good spot right now," Broncos coach Vance Joseph said after a Wednesday practice that he termed the team's "best" of the year. "We have to continue to do more and push our guys to continue to focus and push forward and get better every day."

TV: 8:30 p.m. ET, NBC. LINE: Broncos -11.5. O/U: 39.5

ABOUT THE BRONCOS (3-1): Denver certainly has its vulnerablities, losing at Buffalo in Week 3 and needing a last-second interception to beat Oakland prior to the bye, but it shredded another NFC East foe in a 42-17 shellacking of Dallas in Week 2. There is nothing wrong with the Broncos' defense, which is yielding a league-low 260.8 yards per game and ranks No. 1 against the run (50.8). Former seventh-round draft pick Trevor Siemian has thrown for seven touchdowns versus four interceptions while averaging 222 yards per game, but he has a dangerous wide receiver tandem in Emmanuel Sanders and Demaryius Thomas. C.J. Anderson has at least 20 rushing attempts in three of four games and averages 4.5 yards per tote.

ABOUT THE GIANTS (0-5): New York also lost a third wide receiver, Dwayne Harris, to a season-ending injury and Sterling Shepard was unable to practice Wednesday, leaving the team scrambling to fill the holes by re-signing Tavarres King and Darius Powe. Running back Paul Perkins also was unable to practice Wednesday, leaving Orleans Darkwa and rookie Wayne Gallman to lead a backfield that ranks 30th in the league (77.8 yards). Manning, who could be staring at Roger Lewis Jr. as his No. 1 wideout, has tossed eight scoring passes and five interceptions while completing a career-best 67.8 percent of his defense. Discord has hit the team with the indefinite suspension of cornerback Dominque Rodgers-Cromartie.

EXTRA POINTS

1. Broncos LB Von Miller has four sacks in his last three games and is 1.5 shy of tying for second place on the team's all-time list.

2. Manning has 1,594 passing yards with 17 TDs and seven interceptions in the last six games versus AFC opponents.

3. Broncos RB Jamaal Charles can become the 11th active player to reach 10,000 yards from scrimmage. He is 87 yards short.

PREDICTION: Broncos 23, Giants 13