Most-Bet HR Prop of MLB Opening Day Cashes as Orioles' O'Neill Homers in 6th Straight Opener

Baltimore Orioles outfielder was the most-bet player to hit a home run at BetMGM, second-most bet at DraftKings.

Brad Senkiw - News Editorat Covers.com
Brad Senkiw • News Editor
Mar 27, 2025 • 17:40 ET • 4 min read
Baltimore Orioles right fielder Tyler O'Neill (9) hits a single against the Toronto Blue Jays during the fifth inning at Rogers Centre. Mandatory Credit: Nick Turchiaro-Imagn Images
Photo By - Imagn Images. Baltimore Orioles right fielder Tyler O'Neill (9) hits a single against the Toronto Blue Jays during the fifth inning at Rogers Centre. Nick Turchiaro-Imagn Images

Tyler O’Neill continued his historic MLB Opening Day home run streak and cashed a lot of prop-bet tickets on Thursday. 

The Baltimore Orioles right fielder went yard in the first game of the season for the sixth consecutive year, extending his MLB record with the bomb in Toronto. With MLB home run prop odds of +400 at BetMGM to have at least one homer, O’Neill had the most-bet prop in the market. 

His homer prop saw more action than such stars as Vladimir Guerrero Jr. (+500), Shohei Ohtani (+450), Juan Soto (+550), and Cody Bellinger (+725). 

O’Neil (+370) was second in bets behind Guerrero Jr. in the home run prop at DraftKings. 

Going deep again

The streak that began when O’Neill took Pittsburgh's Joe Musgrove deep in 2020 as a St. Louis Cardinal stayed alive on Thursday when he crushed a 2-1 pitch from Toronto’s Jose Berrios to right field for a three-run shot. 

It was the first homer off Berrios in O’Neill’s career. During his previous five-year stretch with an Opening Day bomb, O’Neill has only reached double digits for the season three times, including hitting 34 home runs in 2024.  

Some other popular player prop bets at BetMGM included Paul Skenes over 6.5 strikeouts (-175), Luis Severino under 5.5 strikeouts (-150), and Yusei Kikuchi under 6.5 strikeouts (-140). 

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