Clippers vs Spurs Prediction, Picks & Odds for Tonight’s NBA Game

With Kawhi Leonard working his way back, the Clippers have maintained their position as a playoff team in the West. We expect them to leave San Antonio with a win tonight.

Tom Oldfield - Betting Analyst at Covers.com
Tom Oldfield • Betting Analyst
Jan 29, 2025 • 10:38 ET • 4 min read
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This article contains predictions for an old game!

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With Kawhi Leonard ramping up, the Los Angeles Clippers are eyeing another jump in the Western Conference standings, and they get the favorites tag as they visit the San Antonio Spurs tonight.

San Antonio is just back from two games in Paris, and my Clippers vs. Spurs predictions signal déjà vu for the hosts, who’ve lost eight of their last nine matchups against L.A.

Take a closer look at this January 29 battle with my NBA picks and betting angles, including a wager on more magic from The Beard.

Clippers vs Spurs prediction

My best bet
Clippers -4 (-110 at bet365)

My analysis
The Los Angeles Clippers have to rank among this season’s NBA surprises — not just surviving without Paul George and, for a long stretch, Kawhi Leonard, but thriving in the cut-throat West.

At 26-20, the Clippers have won six of their last nine contests, and they’re 28-17-1 ATS this year. If Kawhi can stay healthy, even on a lower minutes load, there’s a case for L.A. grabbing homecourt advantage for the first round of the playoffs.

I’m buying into that recent form and laying the points with the Clippers tonight against a San Antonio Spurs team that’s 3-7 in their last 10 contests. The Spurs were on the receiving end of a 136-98 blowout against the Pacers in Paris on Sunday, and their defense has fallen off a cliff lately, allowing 128 points or more in four of the past five outings.

Then there’s the after-effects from San Antonio’s hectic week in Europe. Despite the hosts’ 12-10 mark at Frost Bank Center, I’m factoring in a sluggish start as the jet lag wears off.

An L.A. offense powered by Leonard, James Harden, and Norman Powell should really test the Spurs’ wing defenders, and I see all three of those scorers targeting the Chris Paul matchup while steering clear of Victor Wembanyama in the paint.

The Clippers are just 9-12 on their travels this season, but if you zoom out a bit further, they’re 25-18 across their last 43 road games, and they’ve covered the spread in six of their last nine clashes with the Spurs.

Clippers vs Spurs same-game parlay

Clippers -4

James Harden Over 15.5 rebounds + assists

Victor Wembanyama Over 24.5 points

We’ve seen some vintage Harden moments this season, with The Beard embracing a heavy workload and making contributions all over the box score. Tonight, I’m focusing on his rebounds + assists combo prop, where the line feels too low at 15.5.

Harden has gone past this number in five of his last eight outings, including a 13-assist, 12-rebound night against the Wizards last week, and he’s finished with double-digit dimes in six of his past eight contests. With Ivica Zubac trying to box out Wemby, Harden should walk into some easy boards, too.

I’m rounding out my SGP with a Wembanyama prop. Wemby delivered a 30-point masterpiece against the Pacers in the first of the two Paris games, and he poured in 27 points against the Clippers in late December.

He’s still putting up streaky numbers from beyond the arc, but that hasn’t discouraged him from jacking up 3-pointers, and he’s knocked down at least two triples in every game this month. As San Antonio’s No.1 scoring option, I like his chance of reaching the 25-point mark tonight.

Learn how to bet a same-game parlay with these helpful tips and strategies.

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Clippers vs Spurs odds

Clippers vs Spurs live odds

Clippers vs Spurs opening odds

  • Spread: Los Angeles -3 | San Antonio +3
  • Moneyline: Los Angeles -150 | San Antonio +125
  • Over/Under: Over 224 | Under 224

Odds courtesy of bet365.

Clippers vs Spurs spread and Over/Under analysis

  • The Clippers enter as clear road favorites — and the line has crept up after opening at -3.

  • San Antonio has lost three in a row at Frost Bank Center and is just 2-7 ATS in its last nine games.

  • The Under is 17-29 for the Clippers this season, and it’s hit in seven of the past 10 meetings between these teams.

  • The Spurs have served up six straight Overs, largely due to defensive frailties, and the Over is 24-19-1 overall for the hosts this year.

Clippers vs Spurs trend

The first-half Under is 47-33 in San Antonio's last 80 games. Find more NBA betting trends for Clippers vs. Spurs.

How to watch Clippers vs Spurs

Location Frost Bank Center, San Antonio, Texas
Date Wednesday, 1-29-2025
Tip-off 8:00 p.m. ET
TV FDSN SC, FDSN SW

Clippers vs Spurs latest injuries

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Tom Oldfield - Covers
Betting Analyst

Tom Oldfield’s sports writing journey over the past 20 years has taken him from the Premier League and Champions League to the NFL, NBA, WNBA and MLB, with a wide range of articles and betting previews. Tom has worked closely with London’s Sportsbeat sports news agency as well as (thrillingly!) covering the Toronto Raptors’ 2019 NBA championship run, and he has appeared on BBC World Service and The Back Page podcast.

A graduate of the University of Nottingham in the UK, he is the author of biographies on Cristiano Ronaldo, Rafael Nadal, Gary Neville and Cesc Fabregas, and he co-authors a long-running series of children’s soccer books with his brother, Matt.

As a regular bettor across the top sports leagues, particularly with FanDuel and bet365, he is well versed on all the major markets and the next big game is rarely far from his thoughts. The best betting advice he has received is to monitor multiple sportsbooks to grab the best possible value.

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