Lakers vs Grizzlies Picks and Predictions: L.A. Can't Keep Up

L.A. is hoping to build some momentum, but Memphis already has it and looks like the better team. As the two face off Wednesday night, find out if a growing spread still gives value to the favorite as we break down our Lakers vs Grizzlies picks.

Zachary Cohen - Contributor at Covers.com
Dec 29, 2021 • 10:45 ET • 4 min read
Jaren Jackson Jr. Memphis Grizzlies NBA
Photo By - USA TODAY Sports

The Los Angeles Lakers snapped a five-game losing streak with a win over the Houston Rockets last night, and they’ll now look to earn a second road win in a row when they take on the Memphis Grizzlies at FedExForum. 

Will Los Angeles find a way to earn back-to-back road victories? Keep reading our Lakers vs. Grizzlies NBA picks and predictions for Wednesday, December 29. 

Lakers vs Grizzlies odds

Odds via the Covers Line, an average comprised of odds from multiple sportsbooks.

The Grizzlies are laying 6 on most books in this game, but they can be found as a 4.5 or 5.5 favorite at select books. The line opened at 4.5, so there has been some significant movement. The total, meanwhile, opened at 228.5 and is now 227.5 almost everywhere.  

Use the live odds widget above to track any future line movements right until tip-off and be sure to check out the full NBA odds before betting to ensure you get the best number.

Lakers vs Grizzlies predictions

Predictions made on 12/29/2021 at 10:00 a.m. ET.
Click on each prediction to jump to the full analysis.

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Lakers vs Grizzlies game info

Location: FedEx Forum, Memphis, TB
Date: Wednesday, December 29, 2021
Tip-off: 8:00 p.m. ET
TV: SNLA, BSSE, NBATV

Lakers vs Grizzlies betting preview

Injuries

Lakers: Wayne Ellington G (Doubtful), Austin Reaves G (Doubtful), Trevor Ariza F (Doubtful), Kent Bazemore F (Doubtful), Rajon Rondo G (Out), Anthony Davis F (Out), Kendrick Nunn G (Out).
Grizzlies: John Konchar G (Out), Ziaire Williams F (Out), Santi Aldama C (Out), Jarrett Culver F (out), Yves Pons F (Out), Dillon Brooks F (Out), De’Anthony Melton G (Out), Sam Merrill G (Out).
Find our latest NBA injury reports.

Betting trend to know

The Lakers are 7-19 against the spread in their last 26 games following an against-the-spread win. Find more NBA betting trends for Lakers vs. Grizzlies.

Lakers vs Grizzlies picks and predictions

Our predictions are compiled from the analysis of the spread and total and are indications of where we are leaning for this game.
Our best bet is the play that we like the most for this game, which we would actually put some of our bankroll behind.

The Grizzlies are coming off of a victory over the Phoenix Suns at the Footprint Center, so it might be time for people to start taking this team a bit more seriously. Memphis has proven itself as a legitimate threat in the Western Conference, and the Grizzlies have to be feeling good about this meeting with the Lakers. 

Los Angeles might have earned a victory last night, but that win came against the Houston Rockets. That certainly doesn’t undo the fact that the Lakers come into this one after having lost five of their last six, and they could also be tired with this being the second night of a back-to-back. 

Also, considering how poorly the Lakers have played defensively coming into this game, it’s hard to imagine Ja Morant not carving this Los Angeles group up. The Lakers do not have anybody that can stop Morant from getting to the basket, and they also don’t have anybody that matches up well with Jaren Jackson Jr. That’s a matchup that could haunt Los Angeles with Davis still not back. 

Also, Russell Westbrook could struggle in this game tonight, as he’s a turnover machine and the Grizzlies have a number of guys that get their hands on the basketball with regularity. 

Prediction: Grizzlies -4.5 (-115)

The Lakers might be coming off of a victory in their last game, but this team is still giving up a ton of points lately. Los Angeles has gone Over the total in four of its last five games, and the team has allowed 121.2 points per game in that span. With a matchup on deck against a Memphis team that is averaging 120.5 points per game over its last two contests, it’s hard to imagine the Lakers turning in a good defensive effort here. 

You should probably expect this to turn into a shootout. Not only has Los Angeles played some high-scoring games as of late, but the Over is also 3-0 in Memphis’ last three games. It’s also 11-8-1 in Memphis’ home games this year and 7-3-1 in games against Pacific division opponents on the season. 

Prediction: Over 227.5 (-110)

With the line still available at 4.5, it’s a no-brainer to jump on the Grizzlies in this game. However, it’s still worth taking up to 6, if that’s all you can get. Memphis is already 2-0 against the spread in games against Los Angeles this season, and the Grizzlies beat them by 13 the last time they played. 

The Grizzlies are currently sixth in the league in offensive rating and facing a Lakers team with the 25th-ranked defensive rating over the last six games. This game has the potential to get ugly, as it’s just unlikely that Los Angeles will be able to stop Memphis — especially with Davis out. 

Pick: Grizzlies -4.5 (-115)

NBA parlays

Did you know that if you parlayed today’s NBA Lakers vs. Grizzlies predictions and picks in a single-game parlay, you could win $25.69 on a $10 bet?

Use our NBA parlay calculator to create your own parlays and see their potential payouts.

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