The Mississippi State Bulldogs (15-11, 6-7) and Missouri Tigers (10-16, 4-9) are getting set for the second half of a home-and-home series.
These teams played Friday night that saw the Bulldogs run away with a 19-point win at home. Now, the Bulldogs are on the road as 4.5-point favorites.
Can they go two-for-two or will the Tigers get their revenge at home? Read our college basketball betting picks and predictions for Mississippi State vs. Missouri to find out.
Mississippi State vs Missouri odds
This odds widget represents the best odds available for each betting market from regulated sportsbooks.
The Bulldogs opened as 5-point favorites and have jumped around between -4.5 and -5.5, settling at -4.5 at the time of writing. The total hit the board opened at 133 and has ticked down to 132.5 as of 1:00 p.m. ET.
Use the live odds widget above to track any future line movements right up until tip-off and be sure to check out the full college basketball odds before placing your bets.
Mississippi State vs Missouri predictions
- Prediction: Mississippi State -4.5 (-110)
- Prediction: Over 132.5 (-110)
- Best bet: Mississippi State -4.5 (-110)
Predictions made on 2/20/2022 at 3:00 p.m. ET.
Click on each prediction to jump to the full analysis.
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Mississippi State vs Missouri game info
• Location: Mizzou Arena, Columbia, MO
• Date: Sunday, February 20, 2022
• Tip-off: 8:00 p.m. ET
• TV: SEC Network
Mississippi State at Missouri betting preview
Injuries
Mississippi State: Rocket Watts G (Out).
Missouri: Jordan Wilmore F (Questionable), Anton Brookshire G (Questionable).
Find our latest NCAA basketball injury reports.
Betting trend to know
Mississippi State is 4-0-1 ATS in its last five games as a favorite. Find more NCAA betting trends for Mississippi State vs. Missouri.
Mississippi State vs Missouri picks and predictions
Our predictions are compiled from the analysis of the spread and total and are indications of where we are leaning for this game.
Our best bet is the play that we like the most for this game, which we would actually put some of our bankroll behind.
Spread analysis
In the first of two meetings on Friday, the Bulldogs jumped out to an 11-point lead in the first half and ultimately put them away 68-49.
Mississippi State shot 49.1% from the floor and won the turnover and rebounding battles all while holding Missouri to just 31.4% shooting and 3-17 from beyond the arc.
Missouri has struggled all season long on the offensive end, ranking just 149th in adjusted offensive efficiency and averaging just 64.4 points per game. That's good for 304th of 358 eligible teams.
Mississippi State, though only 6-7 in SEC action, is 39th on KenPom's rankings, including a 29th-best mark in adjusted offensive efficiency.
Other than being in their home gym this time around, it's hard to find an edge for the Tigers that makes this matchup play out much differently than the first one.
The Bulldogs are better in just about every offensive and defensive category, and just crushed the Tigers by 19 as 11-point favorites.
The only cause for pause when backing the Bulldogs is their history on the road.
They're 0-7 SU (3-4 ATS) away from home this season but have played the toughest teams on their schedule on the road thus far, including Kentucky, Texas Tech, Arkansas, LSU, Alabama, and more.
Tonight will be different. They may not win by 19 like on Friday, but they'll do enough to clear the much smaller number.
Prediction: Mississippi State -4.5 (-110)
Over/Under analysis
Friday's matchup closed with a total of 135 and stayed well under at just 117 points.
But in that game, the Tigers' offense posted a dreadful 49 points, and both teams combined for only six 3-point makes on a 20.6% clip.
While neither of these teams lights it up from the perimeter, they both average 5+ makes from deep and should shoot the ball better tonight.
At home, the Tigers' offense should get much closer to their season average of 65 points and both sides should shoot better than they did Friday night.
It's only a lean as the Tigers' offense is among the more inept within the SEC but as bad as the Tigers are onoffensive, the Bulldogs are as good.
Prediction: Over 132.5 (-110)
Best bet
While there's some concern with betting the Over in this game, the Bulldogs against the small number is the right play.
The Tigers just won't have enough offense to stay around over the course of 40 minutes, especially if they go down early like they did Friday night.
Mississippi State is the far superior team and will showcase that on both ends. Lay the small number.
Pick: Mississippi State -4.5 (-110)
Did you know that if you parlayed our Mississippi State vs. Missouri picks, you could win $26.45 on a $10 bet?
Use our college basketball parlay calculator to create your own parlays and see their potential payouts.
