Final Four Odds and Predictions: March Madness Picks 2025

Now is the perfect time to break down the March Madness Final Four odds as we inch closer to the end of the college basketball regular season.

Chris Gregory - Publishing Editor at Covers.com
Chris Gregory • Publishing Editor
Feb 19, 2025 • 16:05 ET • 4 min read
Final Four odds
Photo By - Imagn Images. Duke Blue Devils forward Cooper Flagg.

The start of the NCAA Tournament is drawing closer. Auburn, Duke, Houston and Iowa State are expected to be top seeds at the start of the Big Dance and all have low odds to reach the Final Four in San Antonio. Final Four odds show Auburn (-115) and Duke (-115) as the current betting favorites.

2025 Final Four odds

Team Final Four odds
Auburn Auburn -150
Duke Duke -115
Florida Florida +160
Alabama Alabama +175
Houston Houston +175
Iowa State Iowa State +320
Tennessee Tennessee +350
Texas A&M Texas A&M +600
St. John's St. John's +650
Purdue Purdue +750

Odds courtesy of bet365 on 2-19.

Programs with the most Final Four appearances

Program Final Four appearances
Warriors North Carolina 21
Warriors UCLA 19
Browns Duke 17
Warriors Kentucky 17
Warriors Kansas 16
Warriors Ohio State 11
Warriors Michigan State 10
Warriors Louisville 10
Suns Michigan 8
Warriors Indiana 8

March Madness by the numbers

Fact Stat
Most March Madness appearances without a championship 30 (Purdue Boilermakers)
Odds of a No. 16 seed pulling off an upset 1 in 150
Odds of a perfect March Madness bracket  1 in 9.2 quintillion
Most Final Four appearances 21 (North Carolina)
Most March Madness championships by a coach 10 (John Wooden)
Most March Madness career wins by a coach 97 (Mike Krzyzewski)
Most career points scored during March Madness 407 (Christian Laettner, Duke)
Most points scored in a March Madness game 61 (Austin Carr, Notre Dame)

Final Four FAQ

Pages related to this topic

Chris Gregory Covers.com
Publishing Editor

In his three years on the Covers editorial team, Chris Gregory has helped bolster the site’s PGA Tour and college football coverage, though his love for Rory McIlroy and the Buckeyes is often met with disappointment. He brings a journalism and marketing background to his work as a Publishing Editor and has appeared on Jason Logan’s Sharp 600 to talk about the Masters and golf’s other majors.

His best betting advice? Stay away from betting your favorite teams; it’ll only make the hurt worse.

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