March Madness Odds For Men's NCAA Tournament 2025

For the first time since 2008, all No. 1 seeds made it to the closing weekend. But the Duke Blue Devils, who were atop the college basketball odds, were knocked off their perch by the Houston Cougars.

Meanwhile, the Florida Gators eliminated the Auburn Tigers in an instant classic.

Here's a look at the National Championship odds as we get ready to wrap up the March Madness bracket on Monday, April 7.

March Madness odds

Below is a look at the latest March Madness odds.

March Madness favorites

Check out our list of the best March Madness betting sites when you're ready to make your wager.

  Florida Gators

The Florida Gators probably had one scare too many on their path to the Final Four, but they're still standing... yeah yeah yeah...

Walter Clayton has been the star for Florida, helping his team when it needed him most in comeback wins over UConn and Texas Tech. Can he have another magical moment vs. Houston?

 Houston Cougars

Houston has been a staple of the Big Dance for the past decade, and the Cougars are once again on a deep run thanks to the top defense in the nation. If you have any doubts about their D, just look at Tennessee's first-half box score.

Houston conquered the nation's most dangerous offense in Duke, and they'll look to handle business again on Monday.

Check out my Florida vs. Houston prediction ahead of tip-off for more in-depth analysis.

March Madness odds over time

March Madness opening odds

• Duke: +1100
• Kansas: +1100
• UConn: +1200
• Houston: +1400
• North Carolina: +1600
• Kentucky: +1800
• Alabama: +2000
• Gonzaga: +2000
• Arizona: +2000
• Baylor: +2000
• Tennessee: +2500
• Michigan State: +2500
• Iowa State: +3000
• Auburn: +3000
• Texas: +3000
• Marquette: +3500
• Creighton: +3500
• Florida: +4000
• Illinois: +4000
• Arkansas: +4000
• Villanova: +4000

To be honest, the opening March Madness odds look pretty much the same year in and year out. Sportsbooks take blind action on the bluebloods of college hoops, so you’ll always find Duke, North Carolina, Kentucky, Kansas, and a few perennial powerhouse programs at the top of the board.

The Auburn Tigers will likely make anyone holding a NCAA title ticket at +3000 very happy come April 7. The Tigers’ dominance sees the most significant movement from the opening price, currently sitting as near co-favorites with Duke.

Auburn’s SEC rivals, the Alabama Crimson Tide and Florida Gators, saw significant adjustments from their opening odds to win March Madness as well. Even with the Tide’s recent tumble, Alabama went from +2000 to +1200, and the Gators chomped their way from +4000 to +700.

March Madness betting splits

Highest ticket percentage:
•    Duke 14.1%
•    Florida 9.1%
•    Michigan State 8.7%

Highest handle percentage:
•    Duke 40.5%
•    Florida 11.7%
•    Houston 8.9%

Biggest liabilities:
•    Duke
•    Michigan State 
•    St. John's 

All data courtesy of BetMGM.

"Duke losing in the Final Four was a great result for BetMGM," said Seamus Magee, Trading Manager, BetMGM. "The sportsbook is cheering for Houston to upset Florida in the championship game."

Popular March Madness markets

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Past March Madness winners

March Madness trends

• Of the 20 teams that have entered the tournament with undefeated records, only seven have gone on to win the national championship.

• Only 13 teams successfully defended their national championship the following season.

• UCLA has the most NCAA titles of all time (11), although the Bruins have not won the tournament since 1995.

• A No. 1 seeded team has won the national championship 59.1% of the time since regional seeding was introduced in 1979.

March Madness Title Odds FAQs

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