College Football Playoff Odds: Spreads, Moneylines, and Totals for All 4 First-Round Games

The first edition of the 12-team College Football Playoff is finally here, with Notre Dame, Penn State, Texas, and Ohio State all gearing up to host first-round matchups.

Chris Gregory - Publishing Editor at Covers.com
Chris Gregory • Publishing Editor
Dec 9, 2024 • 14:07 ET • 4 min read
Texas Longhorns quarterback Quinn Ewers (3) drops back to pass against the Georgia Bulldogs.
Photo By - Imagn Images. Texas Longhorns quarterback Quinn Ewers (3) drops back to pass against the Georgia Bulldogs

A new era of postseason college football kicks off in just under two weeks, with fans getting their hands on the first-ever 12-team College Football Playoff bracket.

The college football national championship odds have made their move based on each team's projected path to a title, and our college football picks break down where those paths begin for those playing first-round games.

2024 CFP First-Round Odds

No. 10 Indiana vs No. 7 Notre Dame

  • Location: Notre Dame Stadium, Notre Dame, IN
  • Kick-off: 8:00 p.m. ET
  • TV: ESPN, ABC

The key to Indiana's hopes (+7.5) in this game will be how this Kurtis Rourke-led passing attack fares against one of the best secondaries in the nation, one that ranks Top 5 in any number of related metrics. Considering the 68 yards, eight completions, and no scoring strikes he logged against a comparable Ohio State secondary a few weeks ago, this might be a particularly rough evening.

And while slowing Notre Dame's ground game is a tall task for anyone (second in yards per carry, 6.3), the Hoosiers rank second in the nation in opponent yards per carry. If this total of 50.5 creeps up at any point, I'll be jumping on the Under.

No. 11 SMU vs No. 6 Penn State

  • Location: Beaver Stadium, University Park, PA
  • Kick-off: 12:00 p.m. ET
  • TV: TNT

The pressure will certainly mount on James Franklin in the lead-up to this game, but that's not to say he won't be thrilled with where it fell in the bracket.

And while I expect Penn State (-8.5) to pull away at some point, it's not a thought to be trusted. Instead, target the Over. The Nittany Lions have scored 35+ points in five of their last six and SMU's been doing much of the same (36.8 ppg on the season).  

No. 12 Clemson vs No. 5 Texas

  • Location: DKR-Texas Memorial Stadium, Austin, TX
  • Kick-off: 4:00 p.m. ET
  • TV: TNT

This could be a much tougher test for Texas than this 10.5-point spread suggests, and if I were to call my shot on one first-round upset, this would be it. This Longhorns offense has mustered just one offensive touchdown since halftime of Rivalry Week (six full quarters and an OT).

Unlike Indiana and SMU above, Dabo Swinney has oodles of postseason experience with Clemson. It's partly why the Tigers were able to win the ACC title game as underdogs and why I view Clemson +11 as the best bet.

No. 9 Tennessee vs No. 8 Ohio State

  • Location: Ohio Stadium, Columbus, OH
  • Kick-off: 8:00 p.m. ET
  • TV: ESPN, ABC

While Ohio State (-7.5) and its returning seniors won't be able to avenge that ugly Michigan loss, a deep run in the College Football Playoff — starting with one final home game against Tennessee — would certainly serve as a worthy consolation prize.

I expect this No. 1-ranked Buckeyes scoring defense to keep freshman quarterback Nico Iamaleava at bay, and once you factor in Ohio State's ongoing offensive line issues, scoring could be particularly hard to come by. I have my eyes on the Under 47.5.

How important is home-field advantage during the first round?

As a general rule of thumb, most oddsmakers believe home-field advantage to be worth about three points to any given spread, though some tougher road environments could give a 3.5-point edge to the home side (think Kyle Field or Tiger Stadium).

None of the four programs hosting in Round 1 are undefeated at home this season, but Penn State likely has the most notable home-field advantage. Happy Valley's noise can be tough on opposing offenses, with opponents scoring just north of 11 points per game in Penn State's seven home games this season.

2024 College Football Playoff Championship Odds

The Oregon Ducks may have started slow, but they’ve quickly silenced any doubts and have emerged as a true national title contender. Their statement win over Ohio State, followed by a dominant Big Ten Championship Game victory over Penn State, capped off a flawless 13-0 season.

Now, as the No. 1 seed in the College Football Playoff with a coveted first-round bye, Oregon is leading the charge as a top title contender, with odds as short as +310. They’ll be waiting to face the winner of the Tennessee-Ohio State showdown in Round 1, ready to make its championship run.

CFP First Round Odds FAQ

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Chris Gregory Covers.com
Publishing Editor

In his three years on the Covers editorial team, Chris Gregory has helped bolster the site’s PGA Tour and college football coverage, though his love for Rory McIlroy and the Buckeyes is often met with disappointment. He brings a journalism and marketing background to his work as a Publishing Editor and has appeared on Jason Logan’s Sharp 600 to talk about the Masters and golf’s other majors.

His best betting advice? Stay away from betting your favorite teams; it’ll only make the hurt worse.

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