Early Ohio State vs Penn State Predictions, Picks, and Odds for Week 10

For the defense-inclined football fan, this Ohio State vs. Penn State clash will be a thing of beauty. For others, not so much. Expect both stop units to show up and keep this score low.

Rob Paul - Betting Analyst at Covers.com
Rob Paul • Betting Analyst
Oct 28, 2024 • 10:17 ET • 4 min read
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In one of the biggest games of the college football season, Ohio State heads to Happy Valley to take on Penn State in a battle of two Top 4 teams.

In our Ohio State vs. Penn State predictions, we’re expecting a close game led by two devastating defenses with a potential trip to the Big Ten Championship on the line. Read more in our college football picks for Saturday, November 2.

These picks were made early in the week — for our latest Ohio State vs. Penn State predictions.

Ohio State vs Penn State predictions

Early spread lean
Penn State +4 (-110 at BetMGM)

My analysis

While the Penn State Nittany Lions and Ohio State Buckeyes are ranked No. 3 and No. 4, respectively, neither program has quite lived up to it this season. Both teams are 3-4 ATS and have had hiccups along the way.

With that said, Penn State is built to keep this game close, assuming starting QB Drew Allar is healthy enough to play. The Nittany Lions defense is one of the best in the country — third in SP+ — and should be able to slow the Buckeyes’ offensive attack enough to cover the spread.

The loss of potential All-American left tackle Josh Simmons to a season-ending injury has clearly affected Ohio State’s offense. The Buckeyes only put up 285 total yards and 21 points against a Nebraska defense that’s eighth in SP+.

The run game was non-existent in the four-point win, and Will Howard was constantly under pressure. Ohio State’s biggest question coming into the season was the offensive line, and taking the best player out of its front has thrown the offense out of whack.

That was against a Nebraska front seven that might have a player or two drafted, so taking on the Nittany Lions’ front seven will be an issue. Both Abdul Carter and Dani Dennis-Sutton (assuming he’s healthy enough to play) have 20-plus pressures this season and are likely Top-75 picks in the NFL draft.

Obviously, Penn State will need to score to some extent, and that’s why the Nittany Lions covering hinges on Allar being healthy. He has James Franklin’s team ranked fourth in the country in EPA per dropback and he’s been one of the most efficient QBs in college football this season.

Allar is Top 20 in the nation in adjusted completion rate (78.1%) and is one of just three QBs with eight-plus big-time throws and fewer than five turnover-worthy plays, per PFF.

If he can suit up, I expect Penn State to cover, but Ohio State to win somewhere in the ballpark of 23-20. If Allar can’t go, I’d expect the Buckeyes to cover this spread — it will also likely move closer to six points if that’s the case

Early Over/Under lean
Under 47.5 (-110 at BetMGM)

My analysis

These teams aren’t all that different. Both play tremendous defense, are led by QBs who are more efficient than spectacular, and have a pair of running backs that will be playing on Sundays in the future.

With the way both defenses have played, it’s unsurprising that this total is below 50. Ohio State is actually just 3-4 betting the Under this season, but in all three games in which the total has been below 50, it's hit.

Meanwhile, Penn State is 5-2 betting the Under and is similarly 4-0 when the game total is below 50. 

Both defenses are Top 3 in SP+, and while the offenses are both Top 15, the matchups will be difficult with neither QB being dynamic.

The Nittany Lions' top running back Nicholas Singleton has been banged up as of late, and running into a defense that’s No. 3 in EPA per rush and holding opponents to the sixth-fewest rushing yards per game in the country (91.3) will be nearly impossible to overcome.

If the Buckeyes can shut down the run, it will allow their pass rush to get after Allar, who isn’t a major threat as a runner. Ohio State’s Jack Sawyer and JT Tuimoloau have combined for 43 pressures this season with both having a pass rush win rate better than 13%.

Those two are a major reason why the Buckeyes defense is ranked third in EPA per dropback and allowing the eighth-fewest passing yards per game this season (163.1).

Ohio State will have a tough time moving the ball, too. Especially on the ground with the Nittany Lions ranked ninth in EPA per rush on defense and giving up the eighth-fewest rushing yards per game (93.0).

The impact of losing Simmons can’t be overstated, and it was a constant problem against the Cornhuskers, so Penn State will almost certainly exploit the Buckeyes’ offensive line problems.

This is going to be a grind-it-out game that lacks explosive gains and comes down to whichever defense makes more plays. I wouldn’t be shocked if the game total drops down another point or two

Ohio State vs Penn State live odds

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Rob Paul - Contributor at Covers.com
Betting Analyst

Rob has contributed to various sports media outlets since 2018, including FanSided and Pro Football Network, but Covers is the first site he’s worked at that is dedicated solely to the sports betting industry. Before working in sports media full-time, he spent five years as a local community journalist after attending Durham College for journalism and Wilfrid Laurier University for history.

He’s long been involved in sports in one way or another, previously hosting a podcast focused on the NFL draft and college football. Working as a freelance podcast producer, Rob has appeared on numerous sports podcasts and college football shows. He's also been a guest on SportsTalk Mississippi, discussing the NFL draft.

One of his favorite things about the sports betting industry is the way it helps shine a light on sports that get less coverage. He’s a diehard player prop bettor who always recommends using stats and analytics to identify the best players to back before placing a bet.

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