Oregon vs Washington Odds, Picks, and Predictions: Washington Gets the Dub

It’s only mid-October we could already be treated to college football's Game of the Year as Washington hosts Oregon in an epic Pac-12 battle that promises scoreboard fireworks.

Both the Ducks and Huskies enter this matchup with perfect 5-0 records behind elite quarterback play. Bo Nix and Michael Penix Jr. spearhead arguably the two best offenses in the nation. And not only will the winner have a leg up in the race for a spot in the conference title game, but likely in the Heisman Trophy odds as well.

The Huskies sit as slight home favorites in this matchup but does the total stand a chance of not being toppled by these two high-octane offenses?

I break down the college football odds and bring you my best bet in college football picks and predictions — Oregon vs. Washington on October 14. 

Oregon vs Washington best odds

Oregon vs Washington picks and predictions

What a matchup. This game is going to be epic.

Oregon enters this game at 5-0 straight up and against the spread. The Ducks rank second in the nation in scoring offense, third in yards per play, and third in opponent yards per play. The offensive coordinator looks like he may have unlocked the best version of Bo Nix yet.

Nix has thrown for 1,459 yards while completing a ridiculous 80.4% of his passes with 15 touchdowns and maybe most importantly just one interception.

On the other side, the Washington Huskies are also 5-0 SU and 3-1-1 ATS, and behind Heisman odds leader Michael Penix Jr.’s massive arm, they rank first in total offense, passing offense, and third in scoring offense.

Now, this game is a coin flip, and the general thought is to take the points with the underdog in a game that is expected to be so close. But at less than a field goal I like laying with Washington here and let me tell you why.

For starters, if it’s between Penix and Nix, Penix is the guy I want under center in a close game. The senior quarterback has been outstanding. He has already thrown for 1,999 yards on 74.7% passing with 16 touchdowns compared to two picks.

Penix also has the luxury of playing behind a tremendous offensive line. And even though Oregon will bring pressure at times, Penix is the perfect guy to deal with that. Penix ranks second in the nation in EPA/Pass when blitzed this season. So, when the pressure gets highest, he shines the brightest.

That has not been the case the Nix over the years. Yes, so far this season has looked different but this will be Oregon’s biggest game of the year by far. 

Speaking of that, Washington has played a much tougher schedule than Oregon to this point, so while the Ducks’ defense has been impressive so far this season, some of those numbers need to be taken with a grain of salt. 

Oregon’s toughest game was arguably against Texas Tech and they needed a fourth-quarter comeback to secure the win in that game. And while the general observation is that the Ducks are the more balanced team on both sides of the ball, Washington ranks a respectable 35th in opponent yards per play vs. FBS opponents this season.

On top of that, I’m wondering if Nix’s turnover road woes will return vs. a ball-hawking Huskies secondary that has already nabbed eight interceptions this season. 

Throw in what should be an electric atmosphere at Husky Stadium on Saturday afternoon and I like Washington to get the job done. Bottom line. I trust Penix more than I do Nix in a high-pressure game.

FanDuel US also is offering a 50% profit boost on one bet for this game, which can increase the value of this play from -122 to +123!

My best bet: Washington -2.5 (-122 at FanDuel | +123 with 50% profit boost)
Picks made at time of writing may not reflect live odds.

Oregon vs Washington same-game parlay

Washington -2.5

Penix 350+ passing yards

Nix Over 20.5 rushing yards

50% boost available

+471 +706 at FanDuel

Our same-game parlay as always starts with my best bet, which was of course, Washington -2.5. If Washington wins this game, it means Penix balled out. He has thrown for at least 300 yards in all five games this season, and at least 363 in four of those games. Last year against Oregon in Eugene, he threw for 408 yards. So I’m adding him to throw for 350+ on Saturday.

While I think Washington pulls this one out and cover the short home chalk, it won’t be easy. And in a “do-whatever-it-takes” kind of game, I’m expecting Nix to use his legs a little more in this one. His rushing yardage prop is set at 20.5. He’s only gone Over that number once this season. That’s because he generally hasn’t had to use his legs this year. But the one time was in Oregon’s only other close game against Texas Tech, where he scrambled for 46 yards.

If all three of these legs cash we walk away with a solid +471 payout.

Learn how to bet a same-game parlay with these helpful tips and strategies.

Oregon vs Washington spread and Over/Under analysis

This line has been really interesting to watch this week. Washington opened this epic Pac-12 class as 3-point home favorites and some early action on the Huskies bumped the line to Washington -3.5. But that number was short-lived and then eventually moved down to -2.5. As of writing this on Thursday afternoon, there are more 3s than 2.5s on the board but both are out there. So, if you like Oregon find the +3, and if you’re like me and think Washington gets the job done find that -2.5.

The total is clearly what everyone’s eyes are on in this matchup. These are the second and third-highest-scoring offenses in the country, so why is the total a relatively low 67.5? Well, teams tend to tighten up in big games, and as noted above, both teams do a decent job on the defensive side of the ball. It’s not as easy as "these teams combine to score 90 points per game so take the Over." That said, I would never be comfortable betting on the Under in this matchup of two of the most electrifying offenses in the country. I’m staying away and I’ll just enjoy from my couch if this game flies over the number.

Oregon vs Washington betting trend to know

Washington has hit the Moneyline in their last 10 games for +12.9 units. Find more college football betting trends for Oregon vs Washington.

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