Barcelona vs Inter Milan Predictions, Picks & Odds for Wednesday’s Champions League Match

Barcelona host Inter Milan in the first leg of their Champions League semifinal tie on Wednesday. As Emanuel Rosu explains, Raphinha should be able to leave his mark against a leaky Milan defense.

Emanuel Rosu - Betting Analyst at Covers.com
Emanuel Rosu • Betting Analyst
Apr 28, 2025 • 14:09 ET • 4 min read
Raphinha of FC Barcelona celebrates during the Copa del Rey.
Photo By - Imagn Images. Raphinha of FC Barcelona celebrates during the Copa del Rey.

Barcelona are the big favs in this clash, but Inter are a cultured opponent, and their tactical intelligence might close the gap between the two sides.

Barca are fresh from an El Clasico win against Real Madrid in the Spanish Cup final at the weekend.

They lifted the first of three major trophies they are after this season. After the Cup, they hope to add the league crown and the Champions League as well for a historical treble. Inter Milano are no pushovers, and this tie shouldn't be the walkover Barca's fans dream of.

See why in my Barcelona vs. Inter Milan predictions and free betting picks for Wednesday, April 30.

Barcelona vs Inter Milan picks and predictions

My best bet: Raphinha anytime goalscorer (+162 at Betano)

My analysis
Raphinha has been in great form this season under Hansi Flick. He has been an essential player for Barcelona's success, and numbers back that statement heavily.

In the Champions League alone, he netted 12 times in 12 games. He's the competition's second goalscorer, only behind Dortmund's Guirassy (13), who left the competition in the previous round after being eliminated by Barca.

If goalkeepers see Raphinha having the ball, that should scream "Danger" to their goal. The Brazilian scored eight goals from inside the box, with the other four coming from outside the area. Note that none of his 12 goals were converted penalties.

After this campaign concludes, Raphinha dreams of being a "Ballon d'Or" contender, so he's after as much prominence as possible. Matches like the one against Inter give you that. He is hungry, motivated, and in form, so I will not leave him out of my sight for this game.

Add that Barca's starting striker, Robert Lewandowski, will miss out in this match due to injury, and you'll get an extra reason for Raphinha to take centre stage. Betano pays an excellent +162 for Raphina hitting the net anytime during the game, and I'll take that. 

Barcelona vs Inter Milan same-game parlay (SGP)

Raphinha to score

Over 9.5 corners

Over 4.5 cards

Both Barcelona and Inter have tremendous quality up front. Even if the case of a tight match, corners should play an important role over the 90 minutes. Barcelona averages 4.5 corners per game in the Champions League, with Inter just below 3. I believe set-pieces might be one of the keys to unlock this match, so I'll opt to have over 9.5 corners in my SGP for Wednesday's Champions League football.

Games like these are rarely lacking tension, so I'll translate that into cards. Barcelona are expected to control possession, and Inter should find the right moments to break play before it turns dangerous in front of goal. That often means bookings. I'll also have the over 4.5 bookings included in my SGP, hoping for a nice +950 return.

Learn how to bet a same-game parlay with these helpful tips and strategies.

Barcelona vs Inter Milan odds

Barcelona vs Inter Milan live odds

Barcelona vs Inter Milan opening odds

  • Moneyline: Barcelona -154 | Inter +400
  • Draw: +305
  • Over/Under: Over 2.5 -167 | Under 2.5 +135

Barcelona vs Inter Milan side and Over/Under analysis

  • At least three goals were scored in 89% of the games that Barcelona have won this season in the UEFA Champions League.
  • Barcelona have scored in both halves in 50% of their UEFA Champions League games this season.
  • There have been more goals in the second half in Barcelona's last six matches.
  • Barcelona hasn't conceded in four of their last six home games against Inter Milan.
  • Barcelona are undefeated in their last seven home matches against Inter in all competitions.

How to watch Barcelona vs Inter Milan

Location Estadi Olímpic Lluís Companys, Barcelona, Spain
Date Wednesday, 4-30-2025
Time 3:00 p.m. ET
TV CBS
Weather Sunny conditions.

Barcelona vs Inter Milan key injuries

Barcelona: Alejandro Balde LB (out), Marc Casado CM (out), Marc Bernal CM (out), Robert Lewandowski ST (out).
Inter Milan: Marcus Thuram ST (out).

Not intended for use in MA.
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Emanuel Rosu
Betting Analyst

Emanuel Roșu studied public administration but only to have a degree in something. He was always passionate about football. Writing about it, that is, as we've seen him play and he should feel fortunate he never took that road. He is based in Bucharest and has reported on Champions League, Europa League, and European Championship matches for various media outlets in Europe. He wrote stories for The Guardian, BBC, FourFourTwo, and many more. He represents Romania in the vote for the "Ballon d'Or", the most important individual trophy in world football.

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