Make no mistake, this game between Manchester City and Liverpool isn’t just the biggest game of Sunday, it’s the biggest game of the Premier League season. After 30 games, just one point separates them both and a win for either will put the Premier League title race firmly in their hands.
These are arguably the two best teams on the planet and Sunday’s game is one of those matches you simply can’t miss, so sit back and enjoy. Find out who we think will take this one in our Man City vs. Liverpool picks and predictions for Sunday, April 10.
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Manchester City vs Liverpool match odds
Odds via the Covers Line, an average comprised of odds from multiple sportsbooks.
Compare EPL odds before betting to ensure you get the best number.
Manchester City vs Liverpool betting tips
Predictions made on 4/8/2022 at 10:00 a.m. ET.
Click on each prediction to jump to the full analysis.
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Manchester City vs Liverpool game info
• Location: Etihad Stadium, Manchester, England
• Date: Sunday, April 10, 2022
• Time: 11:30 a.m. ET
• TV: DAZN
Manchester City vs Liverpool betting preview
Weather
Thankfully the Manchester weather will be dry on Sunday, even if it is cloudy. When this game kicks at 4:30 p.m. local it’ll be in the mid-50s but the conditions will be perfect for the sort of free-flowing style that both teams play.
Injuries
Manchester City: Ruben Dias CB (Out), Cole Palmer FW (Out), Benjamin Mendy LB (Out).
Liverpool: Fabinho DM (Questionable).
Manchester City vs Liverpool predictions
Our side and total predictions are based upon our analysis of the line and total in this game. Our best bet is our favorite pick across all markets.
Side analysis
I’ll put it to you simply. If you’re a fan of soccer and the Premier League then you need to be watching Man City vs. Liverpool on Sunday. It’s not just the most important game of the season but it might just be the most important Premier League game in recent years.
That sounds intense but this really feels like a title decider even if we are only at the start of April. These two teams have both been so dominant — losing just five games between them all season — that it doesn’t feel out of the question that they could both win all of their remaining seven games.
Both City and Liverpool are at the forefront of the game right now with each side changing the way the game is played. What makes this such a fascinating clash is that they have very distinctive styles, despite both sharing brilliant coaching and some of the best players on the planet.
With the possible exception of Bayern Munich, these are the world’s best two teams. Whether you love Pep Guardiola’s style that suffocates the opposition with possession, or Jurgen Klopp’s gegenpressing intensity these teams both offer so much excitement.
Neutrals will be happy that both teams come into this in good condition with the hosts only missing Ruben Dias who will be deputized by John Stones alongside Ayermic Laporte. Meanwhile, Liverpool should be able to call upon all of its players with Fabinho expected to be fit to start despite picking up a nasty cut during the Champions League clash with Benfica.
We know full well how both of these managers will send out their teams to play and barring another Champions League final style brain fade from Pep Guardiola he’ll be lining the team up in a 4-3-3 with the midfield anchored by Rodri.
Alongside the Spaniard will be Kevin De Bruyne and either Ilkay Gundogan or Bernardo Silva, although you’d expect that Gundogan might make more sense against Liverpool’s dynamism. The front three will — as always with Pep — be a mystery until the lineups are released but it’s hard to see Phil Foden missing out with the Englishman coming up clutch so regularly for Guardiola in big games.
With the exception of choosing between Naby Keita or Jordan Henderson in midfield, you’d say the rest of Klopp’s best lineup is already well known. Trent Alexander-Arnold will continue to be one of the team’s biggest creative forces despite playing at rightback, while the front three of Mohamed Salah, Sadio Mane, and new boy Luis Diaz are truly devastating.
That Salah/Mane/Diaz trio contains electric pace, guile, and great finishing and can cause City problems; Which is why Guardiola will be so pleased to have Kyle Walker and his speed back in the defense.
Both teams come into this in sensational form. Liverpool has won its past 10 Premier League games, keeping a clean sheet in its past five and having scored at least two goals in five of six. Man City has won eight of its past nine at the City of Manchester Stadium in the league and has scored two or more goals in five of its past six at this stadium.
Those stats really show the problem of looking at past performances to decide on a winner for this one as both teams have completely separated themselves from the rest of the EPL. The last game back in October finished 2-2 and it certainly wouldn’t be a surprise to see that replicated.
When it comes to picking a winner I just can’t, these are two brilliant teams, so I’m going to take the option with the most attractive odds and the one which doesn’t separate them, backing the draw at +275.
Prediction: Draw (+275 at Bet365)
Over/Under analysis
Despite both teams coming into this game on the back of some fine defensive form, I’d still look to back the Over 2.5 goals market here. 57.1% of Man City’s home games have seen three or more goals, as have 66.7% of Liverpool’s trips on the road.
Four of the past five meetings between the two clubs have seen four or more goals and you’d have to think we’ll see Over 2.5 goals here.
The attacking quality on display with Salah, Mane, Diaz, Foden, Raheem Sterling, Riyad Mahrez, and Kevin De Bruyne is just sensational and both teams have a reputation for brilliant attacking play.
There’s always a risk that it could be cagey with neither team wanting to risk losing but with this much quality on display we have to lean on the Over.
Prediction: Over 2.5 goals (-138 at Bet365)
Best bet
As you’d have already read it’s very hard to pick a winner between these teams but the one thing that we can feel certain of is that we’ll see some goals.
The sheer levels of technical and attacking ability of the 22 players who’ll be on the pitch are just so high that it feels a certainty. Both teams will have opportunities to score and the reality is that if either side takes the lead it’ll feel like the opposing team’s season is slipping away and they’ll go gung-ho to try and win it back.
Unless this game gets to 80 minutes goalless and both teams decide to play it out for a draw — with neither gaining or losing ground — then I think we can be confident that both teams will score.
Man City and Liverpool have combined to score 147 goals in the Premier League this season, with the next highest scoring club Chelsea scoring 19 goals less than Liverpool. We will see goals here, that much feels certain.
In their past seven meetings going all the way back to January 2019, there has only been one game in which both teams didn’t score — a 4-0 Man City win back in 2020 — when the Premier League had just been restarted following the pandemic.
At odds of -163, you’re not going to make a fortune backing both teams to score but in a game that feels like it really could go either way this definitely feels like the best bet.
Pick: Both teams to score a goal (-163 at Bet365)
