Atlanta @ San Francisco preview

Last Meeting ( Sep 11, 2018 ) Atlanta 4, San Francisco 1

The Atlanta Braves have won a series in San Francisco for the first time since 2011 and look to complete a three-game sweep of the struggling Giants on Wednesday afternoon. Charlie Culberson belted a two-run homer on Tuesday as the Braves posted a 4-1 victory to improve to 5-1 on their seven-game road trip.

Atlanta's lead in the National League East grew by 1 1/2 games on Tuesday as Philadelphia dropped both ends of its doubleheader against Washington to fall 6 1/2 behind. Nick Markakis reached base three times on two hits and a walk Tuesday and is batting .341 in 41 at-bats this month. The Giants have lost 10 straight contests for just the third time (1985 and 1996) since moving to San Francisco in 1958, and the franchise last lost 11 straight in 1951 while based in New York. The Giants recorded just two runs and nine hits in the first two games of the series and have scored three runs or fewer nine times during their skid.

TV: 3:45 p.m. ET, Facebook-Watch

PITCHING MATCHUP: Braves RH Anibal Sanchez (6-5, 3.09 ERA) vs. Giants LH Derek Holland (7-8, 3.54)

Sanchez struck out eight in five innings against Arizona in his last turn, when he gave up three runs and four hits in a no-decision. The 34-year-old has performed well on the road, going 5-2 with a 3.07 ERA, 1.07 WHIP and .204 opponents' batting average in 11 starts. Sanchez is 4-1 with a 2.13 ERA in six career starts against San Francisco.

Holland settled for a no-decision against Milwaukee last time out after giving up two runs on two hits and five walks over six innings. The 31-year-old has posted a 1.61 ERA over his last five outings but only has a 1-0 record to show for his efforts. Holland's lone appearance against the Braves came on Sept. 12, 2014, when he gave up one run and eight hits in seven innings of a no-decision while with Texas.

WALK-OFFS

1. Braves 1B Freddie Freeman was 0-for-4 with a walk on Tuesday after registering three consecutive two-hit performances.

2. San Francisco INF Ryder Jones (knee) will undergo surgery on Wednesday while 1B Brandon Belt (knee) may require a procedure after the season.

3. Atlanta 3B Johan Camargo (groin) departed Tuesday's contest and will be re-evaluated on Wednesday.

PREDICTION: Braves 6, Giants 3