Indianapolis @ Tennessee preview

Last Meeting ( Dec 30, 2018 ) Indianapolis 33, Tennessee 17

The Tennessee Titans authored one of the more impressive Week 1 victories and will try to start 2-0 for the first time in 11 years when they host the Indianapolis Colts on Sunday. Behind a defense that forced three turnovers and recorded five sacks, the Titans rolled to a 43-13 victory at Cleveland, a popular preseason pick that was favored by nearly a touchdown over Tennessee.

Marcus Mariota threw for 248 yards and three touchdowns -- two to tight end Delanie Walker -- as the Titans stunned a legion of Browns fans itching to see their team live up to its hype. "It's really all about us," Mariota told reporters after the win. "All the outside noise, all those things that people say you can't control. We don't focus on that at all. It was a great team win." The Colts won both meetings with the Titans a year ago by an average of 22 points, but they'll come in as slight underdogs after dropping a 30-24 decision in overtime at the Los Angeles Chargers last week. Marlon Mack was the star for Indianapolis with 174 rushing yards and a touchdown.

TV: 1 p.m. ET, CBS. LINE: Titans -3. O/U: 44.5

ABOUT THE COLTS (0-1): Jacoby Brissett made his first start since 2017 in last Sunday's loss to the Chargers and performed admirably, completing 21-of-27 passes for 190 yards and two TDs with no interceptions. "He made good decisions, he was accurate and he made those decisions quick," offensive coordinator Nick Sirianni told the media. "He had to because they had good edge rushers on the edge coming after him. So I can't say enough of how poised he was in those situations. He played like a veteran. He played like he had played for 10 years." T.Y. Hilton, who had 155 receiving yards and two TDs in the one of the meetings with the Titans in 2018, hauled in eight catches for 87 yards and two scores in Week 1.

ABOUT THE TITANS (1-0): Defensive end Cameron Wake had 2.5 sacks -- one for a safety -- at Cleveland and the 37-year-old was awarded AFC Defensive Player of the Week for his efforts, which included his 100th career sack. Rookie wideout A.J. Brown stood out on the offensive end with three catches for 100 yards, while running back Derrick Henry had a 75-yard TD catch and 84 yards and a score on the ground. Mariota sat out one meeting with the Colts last year and threw for a season-low 85 yards in the other encounter, a 38-10 loss at Indianapolis.

EXTRA POINTS

1. The Titans will retire Steve McNair's No. 9 and Eddie George's No. 27 in a halftime ceremony Sunday.

2. Mack ran for 119 yards and a TD in the most recent game with Tennessee, a 33-17 victory in Nashville, Tenn.

3. Indianapolis has won 18 of the last 21 meetings.

PREDICTION: Titans 27, Colts 21