WrestleMania XLI Night 2 Odds, Picks & Predictions: Cena Eyes History in Las Vegas

John Cena is on the verge of making WWE history, and we expect the 16-time World Champion to raise the belt following Sunday’s main event.

Trevor Knapp - Publishing Editor at Covers.com
Trevor Knapp • Publishing Editor
Apr 19, 2025 • 12:23 ET • 4 min read
John Cena WWE
Photo By - Imagn Images. John Cena during the Men’s Royal Rumble match during the WWE Royal Rumble at Lucas Oil Stadium.

Night 2 of WrestleMania delivers a blockbuster main event as WWE Champion Cody Rhodes puts his title on the line against the legendary John Cena.

With Cena now working as a heel and scheduled for a handful of appearances leading up to his retirement this December, all signs point to the 16-time World Champion seizing the moment. Don’t be surprised if he gets a little help on Sunday night at Allegiant Stadium to pull off one more iconic victory.

Sunday's card will kick off at 7:00 p.m. ET in Las Vegas, with the premium live event airing on Netflix. 

Current WrestleMania 41 odds

Match Favorite Underdog(s)
WWE Championship John Cena (-400) Cody Rhodes (+250)
Women's World Championship Iyo Sky (-130) Bianca Belair (-110), Rhea Ripley (+375)
Sin City Street Fight Drew McIntyre (-800) Damian Priest (+425)
Intercontinental Championship Dominik Mysterio (-400) Bron Breakker (+450), Finn Balor (+500), Penta (+550)
Singles match Logan Paul (-140) AJ Styles (+100)

Odds as of April 19, 2025.

WrestleMania 41 picks

John Cena vs Cody Rhodes (c)

Sunday marks John Cena’s 20th WrestleMania appearance and his 12th title match at the “Show of Shows.”

I’ve been waiting my whole life for Cena to turn heel, and now that it's happened, it’s time for him to carry the belt during the final stretch of his legendary run.

Considering Cody Rhodes has physically gotten the best of Cena in consecutive segments, I expect The Rock to come out at some point during this match, with the Final Boss helping gift Cena No. 17 and breaking Ric Flair’s record.

Pick: John Cena (-400)

Iyo Sky (c) vs Bianca Belair vs Rhea Ripley 

While Rhea Ripley aims to steal the spotlight as a three-time World Champion, Bianca Belair will get the last laugh. Her last singles title came at SummerSlam in August 2023, only to be spoiled minutes later by Iyo Sky's Money in the Bank cash-in.

Although Sky has held the Women’s World Championship for less than two months, she’s had multiple title reigns over the past two years, and it's only a matter of time before Bianca gets payback.

Pick: Bianca Belair (-110)

Drew McIntyre vs Damian Priest

Despite putting others over for the past calendar year (including Damian Priest twice), Drew McIntyre remains one of the best overall talents in WWE, combining brute strength with elite heel mic work.

Vengeful, disdainful, irritable — that’s Drew in a nutshell, and he’s a massive favorite for a reason against Priest. 

Priest’s World Heavyweight Title reign was underwhelming to say the least, and after cashing in his MITB briefcase on Drew at last year's Mania, the Scottish Warrior will redeem himself on the big stage.

Pick: Drew McIntyre (-800)

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Trevor Knapp - Covers
Publishing Editor

Trevor joined the Covers content team as a publishing editor in early 2022. Growing up in Vancouver, he studied Broadcast and Online Journalism at the British Columbia Institute of Technology (BCIT), and interned with TSN and Sportsnet Radio while also writing for the Daily Hive.

An avid bettor of the MLB, NFL, and CFL, Trevor advises his fellow sports bettors to leave their hearts at the door and not hesitate to fade their favorite team. It's a strategy he follows regularly as an apathetic Toronto Blue Jays and Indianapolis Colts fan.

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