DePaul vs Georgetown Prediction, Picks & Odds for Tonight's Big East Tournament Game

With DePaul 2-0 against the Hoyas already this season, take the Blue Demons to keep things closer again.

Ed Scimia - Betting Analyst at Covers.com
Ed Scimia • Betting Analyst
Mar 12, 2025 • 14:12 ET • 4 min read
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This article contains predictions for an old game!

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Isaiah Rivera DePaul NCAAB
Photo By - Imagn Images. Isaiah Rivera drives against Creighton.

Two teams that saw massive improvement this year will look to end their seasons on a high note as the DePaul Blue Demons take on the Georgetown Hoyas in the opening round of the Big East Tournament.

The Blue Demons have gotten the best of the Hoyas twice this year, and I pick them to cover again tonight in my DePaul vs. Georgetown predictions.

Read on to see the full analysis of tonight’s game in my free college basketball picks for Wednesday, March 12.

DePaul vs Georgetown prediction

Who will win DePaul vs Georgetown?

Georgetown has been the better team all year, but the Hoyas have struggled a bit since freshman center Thomas Sorber went down with an injury.

DePaul won the last meeting between these teams to wrap up the regular season, and I’m picking the Blue Demons to pull off the upset tonight.

My best bet: DePaul +4.5 (-110 at bet365)

My analysis
In a vacuum, tonight’s game would be Georgetown’s to lose. The Hoyas are the higher seed, went 17-14 this year, and rate out as the better team by most advanced metrics.

Their defense has been particularly strong for a team not heading to the NCAA Tournament this season, rating 54th in defensive efficiency nationally according to KenPom.

But there are two reasons to doubt Georgetown tonight. First, we’ve already seen DePaul beat this team convincingly twice this year. The Blue Demons won the first game in Georgetown by five back in January, then scored a six-point win at home on Saturday.

I try not to put too much stock in the small sample size of two regular season games, but, notably, DePaul won both despite being an underdog, as they are tonight.

Georgetown also isn’t at full strength for tonight’s matchup. The Sorber injury has looked like a turning point for the Hoyas, as they’ve gone just 2-4 since then. Sorber was named to the Big East all-rookie team after averaging 14.5 points and 8.5 rebounds per game. He also averaged two blocks per contest, and it’s been hard for Georgetown to overcome losing its second-leading scorer and defensive anchor.

In those last six games, the Hoyas have allowed an average of 82 points per game, a dramatic increase from the 68.7 ppg they were giving up for the season. That’s too much for a relatively inefficient Georgetown offense to overcome regularly, especially without Sorber picking up some easy points in the paint.

That was shown in Saturday’s matchup, where the Blue Demons shot 56.6% from the field against a suddenly shaky Georgetown defense. I can’t be sure they can make three straight wins against the Hoyas, but I don’t think they’re real underdogs in this game.

DePaul vs Georgetown same-game parlay (SGP)

DePaul +4.5

Over 144.5

Isaiah Rivera Over 13.5 points

Both matchups this year hit the Over, and Saturday’s game totalled 160 points, well above tonight’s number.

I’ll also take DePaul senior Isaiah Rivera to hit the Over on his total of 13.5 points. While Rivera is only averaging 10.7 ppg for the season, he has scored 14+ points in four of his last five games — including a 21-point outburst against Georgetown on Saturday.

Learn how to bet a same-game parlay with these helpful tips and strategies.

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Take advantage of the early win payout at bet365, where any pre-game CBB moneyline bet gets paid out as a winner if your school goes up by 18+ points!

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DePaul vs Georgetown odds

DePaul vs Georgetown live odds

DePaul vs Georgetown opening odds

  • Spread: DePaul +3.5 | Georgetown -3.5
  • Moneyline: DePaul +154 | Georgetown -190
  • Over/Under: Over 144.5 | Under 144.5

Odds courtesy of bet365

DePaul vs Georgetown betting trend to know

DePaul is 7-1 against the spread in its last eight games against Georgetown. Find more college basketball betting trends for DePaul vs. Georgetown.

How to watch DePaul vs Georgetown

Location Madison Square Garden, New York, NY
Date Wednesday, 3-12-2025
Tip-off 6:30 p.m. ET
TV Peacock

DePaul vs Georgetown key injuries

Not intended for use in MA.
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Ed Scimia - Covers.com
Betting Analyst

Ed Scimia has been writing about the gaming industry for over 15 years. He graduated from Syracuse University with degrees in Magazine Journalism and Political Science in 2003, and has covered major gambling events like the World Series of Poker in his career. Since joining Covers in 2022, Ed has offered his sports betting analysis primarily on MLB, NFL, college football, and college basketball games, but is willing to take on any sport.

His betting strategy focuses more on finding line value based on deviations from the market rather than traditional handicapping, primarily shopping between DraftKings, FanDuel, and Fanatics in his home state of Connecticut, though he’s not afraid to do deep game analysis to find profitable bets at any book.

Outside of gambling, Ed is an avid curler who competes in mixed doubles on the World Curling Tour and runs a popular curling YouTube channel, Chess on Ice. That experience has come in handy during the Olympics, when he has proven to be a successful curling bettor as well. 

Ed's advice to new bettors is to always open multiple sportsbook accounts and check the odds at each before placing any bet. Successful sports betting is about consistently beating the closing line value, which requires finding spots where one book is offering odds far better than the rest of the market and jumping on those opportunities.

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