Every team has at least one game in the books heading into Week 2 of the 2022 college football season, meaning we finally have some real game data to rely on when making predictions.
The No. 20 Kentucky Wildcats visiting the No. 12 Florida Gators stands out as the game of the week, but with most of the Top 25 in action, there are plenty of great options for bettors to look at.
Let’s take a look at a few of the many interesting games on tap this weekend as we break down our best college football parlay picks for Week 2.
Week 2 college football parlay picks
- Texas Tech -2.5 (-122) + UTSA -2.5 (-110) = +247
- TEN vs. PITT Over 66.5 (-110) + Alabama -19.5 (-110) = +264
Click on each pick to jump to the full analysis.
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Parlay Pick 1
PARLAY: Texas Tech -2.5 (-122) + UTSA -2.5 (-110) = +247 (at FanDuel)
Texas Tech -2.5 (+130)
The Houston Cougars struggled in their Week 1 matchup with the Texas-San Antonio Roadrunners, escaping with a 37-35 win after three overtimes. Quarterback Clayton Tune led the Cougars to victory, throwing for 206 yards and three touchdowns in the air while also running for 51 yards and a score.
Houston will need to play better to have a chance on Saturday when it visits the Texas Tech Red Raiders. Texas Tech opened the season last week with a 63-10 thrashing of the Murray State Racers. Three different players scored multiple touchdowns for the Red Raiders, including wide receivers Loic Fouonji and Jerand Bradley, who both went for two scores and over 100 yards on the day.
Houston is coming off a 12-win season. However, one of its two losses came in its home opener against Texas Tech. The Red Raiders scored a 38-21 victory over the Cougars at NRG Stadium last year and will have home-field advantage in the rematch on Saturday.
The trends in this matchup all favor Texas Tech as well. The Red Raiders have covered in all four previous meetings between these teams, while the Cougars are just 1-4 against the spread against teams with winning records.
UTSA -2.5 (-110)
The Roadrunners had every opportunity to beat Houston at home last week. UTSA led 21-7 entering the fourth quarter, and only an illegal substitution penalty kept a Cougars drive alive which resulted in a touchdown that cut the Roadrunners’ lead to seven points.
The UTSA defense held a vaunted Houston offense, which scored 37 points per game last season in check for most of the night, while Roadrunners quarterback Frank Harris looked solid, completing 28 of 43 passes for 337 yards and three touchdowns. All signs suggest that UTSA will be very competitive again in 2022 after a breakout 12-win season last year.
The Army Black Knights faced a solid mid-major opponent of its own last Saturday, falling 38-28 to the Coastal Carolina Chanticleers. Army found most of its success on the ground, running for 202 yards, including 135 yards on just nine carries from running back Tyrell Robinson. It’ll find that path much more difficult against UTSA, which held Houston to just 140 yards on the ground — 51 of which came from the opposing quarterback — in a game that went into triple overtime.
The Roadrunners are not only the better team in this matchup, but they’ve also been great against the spread over the past year. UTSA is 12-5 ATS over its last 17 games, and 5-0 in its last five matchups in September, while Army is just 2-5 ATS over its last seven home games.
Parlay Pick 2
PARLAY: Tennessee vs. Pittsburgh Over 66.5 (-110) + Alabama -19.5 (-110) = +264 (at WynnBet)
Tennessee vs Pittsburgh Over 66.5 (-110)
The Tennessee Volunteers moved into the Top 25 of the AP Poll this week, landing at No. 24 after throttling the Ball State Cardinals 59-10 at home in Week 1. The lopsided win gave the Volunteers plenty of time to give all of their offensive weapons a turn at the helm, while also showing off their defensive prowess by shutting Ball State out for the first half.
Tennessee is coming off of a 7-6 season which ended with an overtime loss to Purdue in the Music City Bowl. The Volunteers found most of their success on the offensive side of the ball, averaging 37.9 points per game against FBS opponents last year, good for seventh in the nation.
Quarterback Hendon Hooker returns to lead the offense yet again, and got off to a fast start against Ball State, throwing for 221 yards and two touchdowns while also scoring twice on the ground.
The Pittsburgh Panthers actually outpaced the Volunteers in offense last year, finishing with 38.7 points per game. While the Panthers have to live without quarterback Kenny Pickett, who will play his trade in the NFL this year, senior Kedon Slovis looks poised to continue the scoring party. Slovis threw for 308 yards and a score in a 38-31 win over the West Virginia Mountaineers last week.
The Volunteers have hit the Over in their last seven games, while the Panthers have gone Over the total in 16 of their past 23 outings. Last year, these two teams combined for 75 points in a 41-34 Pittsburgh win at Knoxville. We can expect another shootout in Pittsburgh this weekend.
Alabama -19.5 (-110)
The consensus No. 1 Alabama Crimson Tide got off to another strong start this year, blowing out Utah State 55-0 at home. Alabama put up 55 points in just three quarters of action before taking its foot off the gas.
Crimson Tide quarterback Bryce Young threw for five touchdowns and ran for a sixth as he begins a run at the Heisman Trophy this season.
The Texas Longhorns had little trouble in their own opener, beating up on the Louisiana-Monroe Warhawks 52-10 at home.
Wide receiver Xavier Worthy and running back Bijan Robinson showed that they are among the top players in the country at their positions, while freshman quarterback Quinn Ewers showed his potential by going 16-for-24 for 225 yards and two touchdowns, albeit with an interception.
While the Longhorns have enough talent to score points against Alabama, the question is whether they can come close to keeping up with the Crimson Tide. The Alabama front seven — led by standout linebacker Will Anderson Jr. — should be able to consistently pressure the inexperienced Ewers into mistakes throughout the game.
On the other side of the ball, the Crimson Tide scored on all eight drives when they played their starters against Utah State, and it remains to be seen if Texas can even slow them down.
The Crimson Tide are 4-0 against the spread in their last four non-conference games and should continue their dominance against non-SEC opponents. Texas has gone 2-6 ATS in its last eight, including a paltry 1-4 mark against its last five opponents with winning records.
