Giants vs Titans Week 1 Picks and Predictions: New York's Defense is Outmatched

New York's defense is vulnerable heading into their season opener on Sunday in Nashville. Facing star RB Derrick Henry and speedy rookie WR Treylon Burks, the Titans could feast on New York in Week 1. Read more in our Giants vs. Titans betting picks.

Jason Logan: Senior Betting Analyst at Covers
Jason Logan • Senior Betting Analyst
Sep 9, 2022 • 23:31 ET • 4 min read
Ryan Tannehill Derrick Henry Tennessee Titans NFL
Photo By - USA TODAY Sports

The New York Giants and Tennessee Titans are on opposite ends of many projections from sharp bettors heading into the 2022 NFL season.

The overhaul in the head office and the hiring of Brian Daboll as head coach had stock in New York on the rise this offseason, while Tennessee is pegged for regression after earning the No. 1 seed in the AFC last year.

However, the G-Men’s improvements could be stunted by a slow transition to this new playbook and injuries once again plaguing this team, after finishing 2021 as one of the most injured rosters in the NFL. 

This has the spread for this non-conference opener bobbing around a dead number of -5.5 with bettors now gun shy on New York but not exactly trusting Tennessee. 

I run down the spread and total for this Week 1 matchup and give my best NFL picks and predictions for Giants at Titans.

Giants vs Titans best odds

Giants vs Titans picks and predictions

There’s a vacuum in the Titans' passing game, with the departure of A.J. Brown and plenty of new faces in the receiver’s room. Tennessee tried to fill that void by drafting Treylon Burks out of Arkansas with the No. 18 pick.

Burks at least fills out Brown’s jersey, coming in at 6-foot-2 and 225 pounds, but had a rough start to training camp. He was sidelined due to asthma in May and his conditioning came under question in minicamp. That doesn’t help his perception in the Week 1 betting markets. His receiving yard prop is sitting at a modest 25.5 yards for a WR coming in No. 2 on the depth chart behind veteran Robert Woods.

But beyond that bad press, he showed resilience and played better than the boxscore in the preseason, running some great routes but getting totally ignored by fellow rookie Malik Willis. The two did hook up in the exhibition finale with Burks making three grabs for 33 yards and a touchdown.

Now, Burks has No. 1 QB Ryan Tannehill under center and that great separation he was creating in the preseason reps won’t go unnoticed.

New York’s defense is undergoing a makeover with a brand-new coordinator in Wink Martindale, who loves to bring blitz and play man-to-man coverage. The Giants' secondary, however, is very thin and was scrambling for bodies on the waiver wire last week. Rodarius Williams is still out and rookie safety Dane Belton is a question mark for Week 1.

Tennessee's play-action playbook will lean on Derrick Henry and the ground game to suck the G-Men into the box, which then opens the door for big hits over the top off misdirection. Burks can run a beautiful deep route and may top this modest receiving total in one strike.

My best bet: Treylon Burks Over 25.5 receiving yards (-115 at Unibet)

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Giants vs Titans betting preview

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Spread analysis Over/Under analysis Game info Injuries Weather Trend to know

Spread analysis

Tennessee opened as high as -6.5 back in the spring when the 2022 schedule dropped and it didn’t see movement until early August, with action on New York moving the number to -6 and eventually -5.5.

Covers Consensus is showing 69% of picks on the home team while sportsbooks like BetMGM are reporting 55% of bets on Tennessee but 56% of the handle riding on the road underdog.

Over/Under analysis

This Over/Under hit the board at 44 points back in May and has stayed relatively still this offseason, with brief dips to 43.5 before coming back to the original post.

Much like the spread, there is a split between ticket count and money wagered, with 59% of bets on the Under but 56% of the handle on the Over.

Giants vs Titans game info

Location: Nissan Stadium, Nashville, TN
Date: Sunday, September 11, 2022
Kickoff: 4:25 p.m. ET
TV: FOX

Giants vs Titans key injuries

Find our latest NFL injury reports.

Giants vs Titans weather

Monitor gametime conditions with our live NFL weather info and learn how weather impacts NFL betting.

Giants vs Titans betting trend to know

Under head coach Mike Vrabel, Tennessee is 13-4 SU, 10-7 ATS, and 11-6 O/U in non-conference games since 2018. It did, however, lose SU and ATS to Arizona at home in Week 1 last season. Find more NFL betting trends for Giants vs. Titans.

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Jason Logan Senior Industry Analyst Covers.com
Senior Betting Analyst

In his 20 years with Covers, “JLo” has seen it all and bet it all. Through the wild west of early Internet gambling to lobbying for legalized sports betting to our brave new wagering world, Jason has been a consistent source of actionable info and entertainment for squares and sharps alike.

Since joining the Covers team back in 2005, he’s honed his handicapping skills to provide audiences with the most thorough insights, blending traditional capping methods with advanced modelling and predictive analysis. Jason has studied the ins and outs of the sports betting business, learning from some of the most successful gamblers in the industry and the biggest sportsbook operators on the planet.

He is under center for Covers during NFL season, taking the points in his infamous “NFL Underdogs” column and representing the Covers Community at the Super Bowl. While he lives for football season, Jason’s first love is basketball and that shows in his in-depth NBA, NCAA, and WNBA betting breakdowns.

On top of being a mainstay in media from coast to coast – WPIX, PHL17, Fox 5 San Diego, WGNO, TSN, SportsNet, ESPN Radio – he’s had his analysis featured in USA Today, MSNBC, ESPN, the Wall Street Journal, CBS, Bloomberg, the L.A. Times, the New York Times and other major publications. You can also find JLo stuffing all the top picks and predictions he can into 10 minutes as the host of Covers’ flagship podcast, The Sharp 600.

His best advice for bettors new and old is “Handicapping isn’t a ‘one size fits all’ process. The impact and importance of information varies from bet to bet. Treat each wager different than the last.”

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