The Arizona Diamondbacks host the Milwaukee Brewers in the second game of this three-game series at Chase Field. MLB odds list Arizona as a -178 favorite, while the total is 8.5.
My Brewers vs. Diamondbacks prediction targets a side in this National League matchup.
Read on for my MLB picks for Saturday, April 12.
Brewers vs Diamondbacks prediction
My Brewers vs Diamondbacks best bet: Brewers moneyline (+150 at FanDuel)
Right-hander Corbin Burnes takes the mound against his former team Saturday evening. While Burnes has historically been a strong pitcher, his performance thus far in 2025 has been concerning.
Through two starts, the right-hander is 0-1 with a 5.79 ERA and 1.93 WHIP. His underlying metrics are equally concerning.
Entering this matchup, Burnes ranks in the bottom third of the league in xERA, average exit velocity, barrel rate, and hard-hit rate.
Meanwhile, right-hander Chad Patrick also takes the mound against his former team.
The Arizona Diamondbacks drafted Patrick in the fourth round of the 2021 MLB Draft but has made his debut for the Milwaukee Brewers this season.
Through three outings, the right-hander is 1-0 with a 2.45 ERA and 1.27 WHIP. Patrick’s analytics suggest that further success is likely.
He ranks in the top half of the league in xERA, xBA, average exit velocity, barrel rate, and hard-hit rate.
Brewers vs Diamondbacks same-game parlay (SGP)
Milwaukee Brewers moneyline
Jackson Chourio 1+ hits
Sal Frelick 1+ hits
If we are backing Milwaukee to win this game, then we need some of its hitters to contribute. There are perhaps no two better candidates than Jackson Chourio and Sal Frelick.
Chourio has gone nuclear since Opening Day, recording a hit in each of his past 13 games. He boasts a .328 batting average over that stretch.
Meanwhile, Frelick is 1-for-3 against Burnes and has recorded 11 hits over the past seven games.
Learn how to bet a same-game parlay with these helpful tips and strategies.
Brewers vs Diamondbacks odds
Brewers vs Diamondbacks live odds
Brewers vs Diamondbacks opening odds
- Moneyline: Milwaukee (+154) | Arizona (-184)
- Run line: Milwaukee +1.5 (-130) | Arizona -1.5 (+108)
- Over/Under: Over 8.5 (+100) | Under 8.5 (-122)
Brewers vs Diamondbacks trend
There have been eight or more total runs scored in eight of Chicago’s past 11 games. Find more MLB betting trends for Brewers vs. Diamondbacks.
How to watch Brewers vs Diamondbacks and game info
| Location | Chase Field, Phoenix, AZ |
| Date | Saturday, 4-12-2025 |
| First pitch | 8:10 p.m. ET |
| TV | FDSNWI, ARID |
| Brewers starting pitcher | Chad Patrick (1-0, 2.45 ERA) |
| Diamondbacks starting pitcher | Corbin Burnes (0-1, 5.79 ERA) |
Brewers vs Diamondbacks latest injuries
Brewers vs Diamondbacks weather
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