Two of the three National League division leaders will square off Tuesday night when the Chicago Cubs host the defending World Series champions in the first of two games.
My Dodgers vs. Cubs predictions expect fireworks, with one of the league’s most dominant batters against left-handed pitchers playing a key role.
Dodgers vs Cubs prediction
My Dodgers vs Cubs best bet: Teoscar Hernandez Over 1.5 hits + runs + RBI (-135 at bet365)
Teoscar Hernandez mashes left-handed pitching. It’s his bread and butter. On a stacked team featuring superstar bats like Shohei Ohtani, Mookie Betts, and Freddie Freeman, it was Hernandez who dominated lefties the most a season ago.
He hit .305 against left-handed pitching with a .311 ISO and .407 wOBA. He bested all everyday Dodgers batters in each of those three categories.
Odds are, he can piece together at least one quality at-bat and hit in this game. If that’s the case, his chances of cashing in a runner — or scoring himself — are pretty good considering all the star-level talent surrounding him in the batting order.
Although Shota Imanaga is an excellent pitcher, he does perform worse against right-handed batters than left-handed batters.
Not to mention, Imanaga has only lasted more than five innings in two of five starts this season. After facing a lefty — although a good one — Hernandez can also look forward to an at-bat or two against a struggling Chicago Cubs bullpen that owns the fifth-highest ERA, and third-highest WHIP, on the season.
Dodgers vs Cubs same-game parlay (SGP)
Teoscar Hernandez Over 1.5 hits + runs + RBI
Mookie Betts Over 1.5 hits + runs + RBI
Kyle Tucker Over 0.5 hits
Mookie Betts recorded at least two hits + runs + RBI in 58% of his games last season. He sits at a solid 50% hit rate this year despite entering play having cleared his line in only two of the last nine.
Notably, Betts posted a hit rate 11% higher on the road last season — the same gap as this year to date. There’s probably something to that!
Sticking with star bats, Kyle Tucker is another name that pops off the page. He’s hitting .302 on the season and has only gone back-to-back games without a knock once.
Learn how to bet a same-game parlay with these helpful tips and strategies.
Dodgers vs Cubs odds
Dodgers vs Cubs live odds
Dodgers vs Cubs opening odds
- Moneyline: Los Angeles -113 | Chicago +102
- Run line: Los Angeles -1.5 (+148) | Chicago +1.5 (-168)
- Over/Under: Over 8 | Under 8
Dodgers vs Cubs trend
The Cubs have cashed the Over in 13 of their last 19 games (+6.60 units / 32% ROI). . Find more MLB betting trends for Dodgers vs. Cubs.
How to watch Dodgers vs Cubs and game info
| Location | Wrigley Field, Chicago, IL |
| Date | Tuesday, 4-22-2025 |
| First pitch | 7:40 p.m. ET |
| TV | SNLA, MARQ |
| Dodgers starting pitcher | Dutstin May (1-1, 1.06 ERA) |
| Cubs starting pitcher | Shota Imanga (2-1, 2.22 ERA) |
Dodgers vs Cubs latest injuries
Dodgers vs Cubs weather
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