Guardians vs Orioles Prediction, Picks, & Odds for Tonight’s MLB Game

The Cleveland Guardians are sending Carlos Carrasco to try and sweep Baltimore, but my MLB picks expect the Orioles to shell him and win by multiple runs.

Rohit Ponnaiya - Betting Analyst at Covers.com
Rohit Ponnaiya • Betting Analyst
Jun 26, 2024 • 11:43 ET • 4 min read
Gunnar Henderson Baltimore Orioles MLB
Photo By - USA TODAY Sports

Two of the best teams in the AL square off on Wednesday night at Camden Yards, where the Baltimore Orioles host the Cleveland Guardians.

Cleveland will look to sweep this series with a win tonight, but my Guardians vs. Orioles predictions are betting on the O's to end their five-game losing streak instead. Here are my MLB picks for June 26.

Guardians vs Orioles prediction

My best bet
Orioles -1.5 (+105 at DraftKings)

My analysis
The Cleveland Guardians have the best record in the majors, but they have a struggling Carlos Carrasco on the mound tonight, and their Statcast analytics indicate major regression at the plate.

Carrasco is coming off the worst season of his career, pitching to a 6.80 ERA with a 1.70 WHIP in 20 starts with the Yankees. While he hasn't been quite as terrible this year, he still has an ugly 5.40 ERA with an OBA of .274 through 13 starts. 

At the plate, the Guardians are second in the majors in scoring with 5.09 runs per game, which is shocking when you consider their peripheral numbers: second-last in barrel rate, 26th in exit velocity, and last in hard-hit rate.

The Baltimore Orioles are the only team in the majors scoring at a higher rate (5.23) than Cleveland, but they back it up with elite analytics: second in the majors in barrel rate and exit velocity while ranking first in hard-hit rate. 

The O's also have the edge on the mound with Grayson Rodriguez getting the start. Rodriguez is coming off an ugly performance against the Astros, but he's generally been very effective. He was lit up in a pair of games against Houston and the Angels, but he's pitched to a 2.45 ERA in his other 11 starts, including a sparkling 2.21 ERA at home over six starts. 

The O's might have lost their first two games in this series, but they should win by multiple runs tonight.

Guardians vs Orioles same-game parlay (SGP)

Orioles -1.5

Grayson Rodriguez Over 4.5 strikeouts

Gunnar Henderson Over 1.5 total bases

The Guardians strike out at the fifth-lowest rate in the majors, but the strikeouts total for Rodriguez is still too low at 4.5. Rodriguez has fanned at least six batters in 10 of 13 starts this year, and he averages 6.5 punchouts per start. 

Gunnar Henderson is second on the AL MVP odds board, and he's third in the majors in total bases (185) and slugging percentage (.607). He's been even better this month, slashing .333/.436/.667, and he'll have the platoon advantage against Carrasco. 

Learn how to bet a same-game parlay with these helpful tips and strategies.

Guardians vs Orioles odds

Guardians vs Orioles live odds

Guardians vs Orioles opening odds

  • Run line: Cleveland +1.5 (-140) | Baltimore -1.5 (+120)
  • Moneyline: Cleveland +145 | Baltimore -170
  • Over/Under: Over 9 (-125) | Under 9 (+105)

Guardians vs Orioles spread and Over/Under analysis

  • Early money has come in on the home side, shifting the Orioles from -170 to -190 on the moneyline.
  • The Guardians are on a seven-game winning streak and have the best record in the majors at 51-26.
  • The Orioles have lost five games in a row but still have the fourth-best record in the majors at 49-30.
  • The Guardians are 3-6 in Carrasco's last nine starts with five of those losses coming by multiple runs. 

Guardians vs Orioles trend

The Orioles have covered the run line in 41 of their last 71 games (+17.45 Units / 21% ROI). Find more MLB betting trends for Guardians vs. Orioles

Guardians vs Orioles game info

Location: Oriole Park at Camden Yards, Baltimore, MD
Date: Wednesday, 6-26-2024
First pitch: 6:35 p.m. ET
TV: BSGL, MASN
Guardians starting pitcher: Carlos Carrasco
(3-6, 5.40 ERA)
Orioles starting pitcher: Grayson Rodriguez
(8-3, 3.82 ERA)

Guardians vs Orioles latest injuries

Guardians vs Orioles weather

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Betting Analyst

With a background playing soccer, rugby, and boxing, combined with a journalism degree, it's little surprise that Rohit gravitated towards the world of sports betting. He specializes in betting on UFC and college basketball, two sports where the eyeball test can tell you a lot more about matchups than any analytics. Rohit has years of experience handicapping NFL and NBA games as well as niche betting markets such as politics and Oscar odds. He's also the resident CFL expert and formerly hosted "The Chez and Ro Show" with former CFL star Davis Sanchez.

You can catch Rohit breaking down every UFC event with Joe Osborne on "P4P Picks" on the Covers YouTube channel and he also has regular appearances on "Before You Bet" with Joe. In addition, he's a regular guest on "By The Book" on the Monumental Sports Network and makes guest appearances on VSIN's "The Handle" and CBS Sports.

Rohit primarily makes his bets at bet365, which offers a wide variety of prop markets, but also has accounts at several others so he can shop around for the best prices. For Rohit, bankroll management is key. He believes you should never bet what you can't afford to lose and maximize those few betting opportunities where books misprice a line.

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