76ers vs Thunder Prediction, Picks & Odds for Tonight’s NBA Game

Quentin Grimes has flourished with the Philadelphia 76ers, and not even the OKC Thunder can slow him down.

Zak Hanshew - Betting Analyst at Covers.com
Zak Hanshew • Betting Analyst
Mar 19, 2025 • 10:27 ET • 4 min read

NBA

Match starts: 6 hrs
OKC
73 %
PHI
27 %
EXPERT PICK - PROP
Quentin Grimes 25+ Points (-125) Quentin Grimes 25+ Points (-125)
Read Analysis
Quentin Grimes Philadelphia 76ers NBA
Photo By - Imagn Images. Grimes gets hype after a play.

The Oklahoma City Thunder have cruised to the best record in the Western Conference and have won nine of their last 10 games. The visiting Philadelphia 76ers haven’t strung together too many wins, but they’ve done a good job keeping things close against superior competition.

My 76ers vs. Thunder predictions expect surging guard Quentin Grimes to stay hot on offense in a high-scoring game at Paycom Center.

Read my NBA picks for March 19 to see how you should bet on Grimes.

76ers vs Thunder prediction

My best bet: Quentin Grimes 25+ points (-125 at bet365)

My analysis
The Luka Doncic trade will go down as one of the worst in the history of the NBA, but the Quentin Grimes trade looks pretty terrible, too. 

Grimes has started 14 straight for the Philadelphia 76ers and averaged 23.4 points. In that span, he’s got five games with at least 30 points, three with at least 35, and two with at least 40 — including his career-high 46-point eruption in Monday’s OT loss to Houston.

Grimes already has more 35-point games as a Sixer than Tobias Harris and Paul George combined in just over a month of running with the first unit. Since becoming a full-time starter, he leads the team in scoring and usage rate (27.0). 

Over the last month, Grimes has been tailed in the scoring department by Tyrese Maxey, Paul George, and Joel Embiid, who will all be out. The next active highest scorer behind Grimes has only averaged 12.7 per game, so to say Grimes will have the green light is an understatement.

The Oklahoma City Thunder sport the best defensive rating in the Association this season at 106.2, but that rating has slipped recently. Over the last five games, OKC ranks 18th at 114.5. In that span, the Thunder have allowed 113.4 points (15th), down from their season average of 107.1. 

Grimes’ scoring prop is set at 25.5 with a price of -120, but I’m perfectly content to take this one at -125 for just a half-point less.

He’s scored at least 25 points in eight of his last 14 — including five straight — and I expect him to do it again in what should be a high-scoring affair.

76ers vs Thunder same-game parlay

Quentin Grimes 25+ points

Over 230.5

Chet Holmgren Over 32.5 points+rebounds+assists

As mentioned above, the Thunder’s defense has fallen off in recent games, while Philly’s offense has been able to score the ball thanks to one of the deepest rotations in the NBA and some monster performances from Grimes.

Philly’s defense has played poorly too, and there should be plenty of scoring opportunities for both teams.

Over the last seven, the Sixers have surrendered 27.4 points, 12.8 rebounds, and five assists to opposing PFs and 25 points, 13.5 rebounds, and 5.1 assists to opposing centers. No matter his position, Chet Holmgren is in a great spot to succeed against Philly's depleted, undersized frontcourt.

Learn how to bet a same-game parlay with these helpful tips and strategies.

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Take advantage of the early win payout at bet365, where any pre-game NBA moneyline bet gets paid out as a winner if your team goes up by 20+ points!

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76ers vs Thunder odds

76ers vs Thunder live odds

76ers vs Thunder opening odds

  • Spread: Philadelphia +10 | Oklahoma City -10
  • Moneyline: Philadelphia +350 | Oklahoma City -450
  • Over/Under: Over 230.5 | Under 230.5

Odds courtesy of bet365

76ers vs Thunder spread and Over/Under analysis

  • Philadelphia has covered in three straight and four of the last five.
  • Oklahoma City has covered in eight of the last 10.
  • The Sixers and Thunder have a combined 75-58-4 record to the Over this season.

76ers vs Thunder trend

The Oklahoma City Thunder have hit the team total Over in 34 of their last 50 games (+15.55 Units / 27% ROI). Find more NBA betting trends for 76ers vs. Thunder.

How to watch 76ers vs Thunder

Location Paycom Center, Oklahoma City, OK
Date Wednesday, 3-19-2025
Tip-off 8:00 p.m. ET
TV NBC Sports Philadelphia, FanDuel Sports Network - Oklahoma

76ers vs Thunder latest injuries

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Zak Hanshew - Covers
Betting Analyst

Zak Hanshew has been covering fantasy sports and sports betting since 2018. In addition to Covers, he has also written for Rotoworld and has spent time at FantasyPros, RotoWire, OwnersBox and Sportsbook Review. In his spare time, he can be found spending time with his wife and four kids, playing his guitar, watching Simpsons re-runs, or getting some shots up on the court.

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