Grizzlies vs Cavaliers Prediction, Picks & Odds for Tonight’s NBA Game

The Cavaliers are deeper and more talented than the Grizzlies regardless of location, but fold in a tremendous home-court advantage for Cleveland, and our NBA betting picks believe the against-the-spread choice is clear.

Phil Naessens - Betting Analyst at Covers.com
Phil Naessens • Betting Analyst
Feb 23, 2025 • 12:55 ET • 4 min read

NBA

Match starts: 2 hrs
CLE
72 %
MEM
28 %
EXPERT PICK - SPREAD
Cavaliers -5.5 (-110) Cavaliers -5.5 (-110)
Read Analysis
Evan Mobley Cleveland Cavaliers NBA
Photo By - Imagn Images. Evan Mobley of the Cleveland Cavaliers dunks the ball.

The Memphis Grizzlies wrap up a five-game road swing when they visit Rocket Mortgage FieldHouse and the Cleveland Cavaliers.

Cleveland is riding a five-game winning streak, and my Grizzlies vs. Cavaliers predictions expect it to continue tonight against road-weary Memphis. 

Read on as I share my NBA picks for Sunday, February 23. 

Grizzlies vs Cavaliers prediction

My best bet
Cavaliers -5.5 (-110 at bet365)

My analysis
The Cleveland Cavaliers are running away with the East primarily because they are dominant at Rocket Mortgage FieldHouse.

Cleveland is 26-4 in their barn, and they’ve covered the number in 20 of 30 home games. They can beat opponents like the Memphis Grizzlies in various ways.

Everything for Cleveland begins with backcourt mates Donovan Mitchell and Darius Garland. The two complement one another well and are exceptional shooters from everywhere.

When their shots aren’t falling, they become willing passers. The Cavs duo are surrounded by teammates who knock down shots while Evan Mobley and Jarrett Allen (questionable) clean up the mess.

The addition of DeAndre Hunter adds scoring punch and makes the Association's third-best bench even deeper. Cleveland’s already-stout defense also improved with the addition of Hunter. 

If anyone does get past this backcourt, Mobley and Allen combine for nearly three blocked shots per game, making it challenging for scorers like Grizzlies guard Ja Morant to reach the cup.

Memphis is a good road team at 16-13 SU and 17-12 ATS, but they are up against a great home team that Hunter improves mightily on both ends of the floor. 

The Grizzlies are on the tail-end of a five-game road swing, and while they will give Cleveland a battle, the thought of returning home with road-weary legs after an already successful road trip may get in their way tonight. 

I’m betting it does, and with or without Allen, I like the Cavaliers to win big.

Grizzlies vs Cavaliers same-game parlay

Cavaliers -5.5

Evan Mobley Over 9.5 rebounds

Ja Morant Under 21.5 points

Mobley has been incredible for the Cavs. When he’s not disrupting shots, he’s snagging caroms from their missed shots or his teammates. 

The Cavs forward has snatched 10+ rebounds in three of five, and with or without Allen, I expect him to grab that many boards tonight. 

I don’t expect Morant to have a big game. Although he has cleared 22+ in two of three games, he’s not a great shooter, and getting to the rim will be difficult against this Cleveland defense. 

Learn how to bet a same-game parlay with these helpful tips and strategies.

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Grizzlies vs Cavaliers odds

Grizzlies vs Cavaliers live odds

Grizzlies vs Cavaliers opening odds

  • Spread: Memphis +6.5 (-110) | Cleveland -6.5 (-110)
  • Moneyline: Memphis +200 | Cleveland -250
  • Over/Under: Over 248.5 (-105) | Under 248.5 (-115)

Odds courtesy of bet365

Grizzlies vs Cavaliers spread and Over/Under analysis

  • Memphis is 4-6 ATS in their previous 10 contests.
  • Cleveland is 20-10 ATS and 7-3 across its last 10.
  • The Over/Under record is 3-7-0 to the Under in their previous 10 meetings.  

Grizzlies vs Cavaliers trend

Cleveland is 20-10 ATS at Rocket Mortgage FieldHouse. Find more NBA betting trends for Grizzlies vs. Cavaliers.

How to watch Grizzlies vs Cavaliers

Location Rocket Mortgage FieldHouse, Cleveland, OH
Date Sunday, 2-23-2025
Tip-off 7:00 p.m. ET
TV ESPN

Grizzlies vs Cavaliers latest injuries

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Phil Naessens
Betting Analyst

Prior to joining Covers in 2022, Phil Naessens spent 38 years as a resident tennis pro in Las Vegas, Mykonos, and Corfu Greece. He’s the past host of the Phil Naessens Show (Armed Forces Radio), and currently hosts the tennis betting podcast, This Week in Tennis.

Phil is the author of the Betting 101 series (MLB, NFL, NCAAF, and Tennis) and has written for numerous publications including SB Nation, FanSided and Lenny Melnick Fantasy Sports. Phil curates the Chip and Charge Tennis Newsletter and pens a weekly tennis column called “10 Things About the ATP Tour," for Passing Shot Productions. 

His favorite sports to bet on are tennis, MLB, WNBA, Euro men’s and women’s hoops, NCAA sports, NFL, and the NBA. Phil has numerous betting accounts in the US and Europe and his best advice is to line shop for the best value possible.

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