Lakers vs 76ers Prediction, Picks & Odds for Tonight’s NBA Game

Don't let the Lakers being on the second half of a road back-to-back deter you from backing another big game from Anthony Davis as he measures up well against the 76ers' banged-up frontcourt.

Zak Hanshew - Betting Analyst at Covers.com
Zak Hanshew • Betting Analyst
Jan 28, 2025 • 11:06 ET • 4 min read
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This article contains predictions for an old game!

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Anthony Davis Los Angeles Lakers NBA
Photo By - Imagn Images.

The Los Angeles Lakers have won four straight, and they’ll look to extend their current win streak when they visit Wells Fargo Center tonight to face the Philadelphia 76ers, who have surprisingly won back-to-back games.

My Lakers vs. 76ers predictions love the Over on Anthony Davis’ combo prop.

Read my NBA picks to see why I love that wager and more ahead of this 7:30 p.m. ET tip on Tuesday, January 28 on TNT.

Lakers vs 76ers prediction

My best bet
Anthony Davis Over 43.5 points + rebounds + assists (-115 at bet365)

My analysis
Anthony Davis went off for season-highs in points (42) and rebounds (23) in last night’s matchup with the Charlotte Hornets, and I fully expect him to carry that momentum into tonight's tilt with the Philadelphia 76ers. But I’m certainly not chasing stats after Monday’s monster production, as Davis has enjoyed sustained excellence over the last month.

Since exiting the Christmas Day matchup with Golden State early, Davis has averaged 27.7 points, 13.8 rebounds, and 3.6 assists, good for 45.1 points + rebounds + assists. AD has hit the Over in seven of those 12, including each of the last two and three of four.

Davis has hit the Over on this line in 21 of 41 games, including 12 of 21 on the road. Tonight’s matchup is a great one, thanks to the Sixers' lack of frontcourt depth and key injuries at center. Both Joel Embiid and Andre Drummond are out, leaving inexperienced and undersized bigs Guerschon Yabusele and Adem Bona to hold things down at center.

Over the last five outings, the Sixers have allowed the third-most rebounds and fourth-most points to opponents. On the season, Philadelphia’s defense has surrendered 39.9 PRAs per game to opposing centers, but over the last seven, the team has given up 45.8 PRAs on average. 

Davis is in prime position to stuff the stat sheet here against an undersized and inexperienced frontcourt. I expect him to comfortably hit the Over on this one and deliver a fifth straight win for the Los Angeles Lakers.

Lakers vs 76ers same-game parlay

Anthony Davis Over 43.5 pts+reb+asts

Lakers moneyline

Tyrese Maxey Over 29.5 points

Neither team has been tremendous against the spread this season. The Lakers are 22-21-1, and the Sixers are 16-28. The Lakers are just 3-5-1 ATS as the away favorite and 9-12-1 on the road overall. 

Philly is 5-14-1 at home and 4-6-1 as the home dog. Los Angeles is 6-13 ATS when favored by at least four points, but the team is 13-6 straight up in those situations. The Lakers are just 12-13 ATS as the favorite but 19-6 straight up. I’m not confident in the Lakers winning by more than four points even against a banged-up Sixers team, but I do think they’ll take the win outright, so I’m rolling with the ML pick.

Tyrese Maxey has been on a roll, averaging 30.5 points across his last 10. In that span, he’s scored at least 30 points five times and scored no fewer than 28. With Paul George and Embiid out again, Maxey will continue shooting with impunity while racking up points.

Learn how to bet a same-game parlay with these helpful tips and strategies.

Cash your ML bets quicker with bet365's early win payout

Take advantage of the early win payout at bet365, where any pre-game NBA moneyline bet gets paid out as a winner if your team goes up by 20+ points!

Learn more about this feature, and all of bet365's offerings, with our comprehensive bet365 review.

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Lakers vs 76ers odds

Lakers vs 76ers live odds

Lakers vs 76ers opening odds

  • Spread: Los Angeles -4 (-105) | Philadelphia +4 (-115)
  • Moneyline: Los Angeles -165 | Philadelphia +140
  • Over/Under: Over 216 (-110) | Under 216 (-110)

Odds courtesy of bet365

Lakers vs 76ers spread and Over/Under analysis

  • Los Angeles has covered in six of the last seven and is 22-21-1 on the season.
  • Philadelphia is just 2-8 ATS across its last 10, bringing the team’s record to 16-28 ATS.
  • The Lakers have hit the Under in four of the last seven and 24 of 44.
  • The 76ers have hit the Over in six of the last seven and are 24-19-1 to the Over this season.

Lakers vs 76ers trend

The Lakers have covered in four of their last 10 head-to-head matchups with the 76ers. Find more NBA betting trends for Lakers vs. 76ers.

How to watch Lakers vs 76ers

Location Wells Fargo Center, Philadelphia, PA
Date Tuesday, 1-28-2025
Tip-off 7:30 p.m. ET
TV TNT, MAX

Lakers vs 76ers latest injuries

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Zak Hanshew - Covers
Betting Analyst

Zak Hanshew has been covering fantasy sports and sports betting since 2018. In addition to Covers, he has also written for Rotoworld and has spent time at FantasyPros, RotoWire, OwnersBox and Sportsbook Review. In his spare time, he can be found spending time with his wife and four kids, playing his guitar, watching Simpsons re-runs, or getting some shots up on the court.

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