Pacers vs 76ers Prediction, Picks & Odds for Tonight’s NBA Game

Pascal Siakam has led the way for the Pacers, and our expert NBA predictions expect Siakam to lead Indiana to cover the massive spread tonight at Philly.

Chris Faria - Betting Analyst at Covers.com
Chris Faria • Betting Analyst
Mar 14, 2025 • 07:50 ET • 4 min read

NBA

Match starts: 7 hrs
PHI
45 %
IND
55 %
EXPERT PICK - SPREAD
Indiana -12.0 (-110) Indiana -12.0 (-110)
Read Analysis
Pascal Siakam of the Indiana Pacers
Photo By - Imagn Images.

The Indiana Pacers snapped a three-game losing skid on Tuesday and will look to get back on a roll when they visit the Philadelphia 76ers at Wells Fargo Center.

The injury-riddled Sixers will be in even worse shape tonight as both Tyrese Maxey (back/finger) and Paul George (groin/knee) remain sidelined.

That’s one of many reasons I’ll be looking for the visitors to cover the spread in my Jazz vs. 76ers predictions and NBA picks for Friday, March 14.

Pacers vs 76ers prediction

My best bet: Indiana Pacers -10.5 (-110 at bet365)

My analysis
The Indiana Pacers eked out a 115-114 win over the Milwaukee Bucks on Tuesday to end their three-game losing streak thanks to a four-point play from Tyrese Haliburton in the waning seconds.

The visitors will have a good chance to pick up a much easier win tonight, though, as they take on the injury-riddled Philadelphia 76ers.

Philly was already without Joel Embiid (knee), but a couple more key names were added to the injury list earlier this month in Tyrese Maxey (back/knee) and Paul George (groin/knee).

Since Maxey’s last game on March 3, the 76ers are 1-5 with an average losing margin of 14.4 points. In fact, Philadelphia has lost by at least 10 points in each of its last five defeats.

Big losses have been a common theme for the 76ers this season, particularly at home. The Sixers own a plus-minus of -4.7 at Wells Fargo Center and have covered the spread in 31.3% of their home games (10-22-1) – the worst mark in the NBA.

The Pacers, meanwhile, own the league’s fifth-best offense at 119.1 ppg and have covered the spread in four of the last five meetings, with each of their last three wins against the 76ers coming by a margin of at least 12 points.

Pacers vs 76ers same-game parlay

Indiana Pacers -10.5

Pascal Siakam 20+ points

Quentin Grimes 25+ points

Pascal Siakam has led the charge offensively for Indiana this month, scoring over 22 ppg and 20+ points in five of his last seven.

That number shouldn’t be too hard for Spicy P to top against a 76ers squad that’s given up 123.3 ppg over its last six.

Quentin Grimes has been one of the only bright spots for the lowly Sixers down the stretch, as he’s averaging 26.1 ppg this month, including a season-high 44 points on March 1.

Grimes has dropped 25+ points in three straight games and five of his last seven.

Learn how to bet a same-game parlay with these helpful tips and strategies.

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Pacers vs 76ers odds

Pacers vs 76ers live odds

Pacers vs 76ers opening odds

  • Spread: Indiana -10.5 (-110) | Philadelphia +10.5 (-110)
  • Moneyline: Indiana (-550) | Philadelphia (+400)
  • Over/Under: Over 229.5 (-110) | Under 229.5 (-110)

Odds courtesy of bet365

Pacers vs 76ers spread and Over/Under analysis

  • The Pacers opened as the big 10.5-point favorite on the road. Both teams have struggled to cover of late with Indiana going 1-4 ATS in its last five and Philly going 1-5 ATS in its last six, but the Pacers have covered the spread in four of the last five meetings.
  • The 76ers have won just two of their last 16 games and have dropped 13 straight vs Eastern Conference opponents.
  • Tonight’s total opened at 229.5 points and these teams usually produce plenty of scoring when they go toe-to-toe. The Over is 8-1 in the last nine meetings and 5-0 in Philadelphia’s last five contests.

Pacers vs 76ers trend

The Philadelphia 76ers have hit the 1H Game Total Over in 11 of their last 14 games at home (+7.50 Units / 46% ROI). Find more NBA betting trends for Pacers vs. 76ers.

How to watch Pacers vs 76ers

Location Wells Fargo Center, Philadelphia, Pennsylvania
Date Friday, 3-14-2025
Tip-off 7:00 p.m. ET
TV FanDuel Sports Network-Indiana, WTHR, NBCSP, TSN

Pacers vs 76ers latest injuries

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Chris Faria - Covers
Betting Analyst

After writing a few pieces for the Varsity newspaper during his time at the University of Toronto, Chris Faria's career in sports truly began in 2019 when he attended the sports journalism program at Centennial College. Since then, he’s covered virtually every sport under the sun, having written for several different outlets including Covers and the Canadian Olympic Committee. A lifelong hockey fan and player, Chris currently works full-time for the National Hockey League.

Outside of hockey, he’s also an avid poker player and mixed martial arts fan, which is coincidentally his favorite sport to bet on – usually in the form of a parlay on bet365. The main lesson he’s learned from years of betting is bankroll management: "Never bet more than you’re comfortable losing and never chase your losses."

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