Liam Smith vs Jessie Vargas Picks: Can Vargas Swing the Upset?

Two former champs collide in the ring Saturday night, both needing a win to remain relevant. Find out which can dig deep for some of the old magic as our Liam Smith vs. Jessie Vargas betting picks break down the best angles.

Danny Howard - Betting Analyst at Covers.com
Danny Howard • Betting Analyst
Apr 30, 2022 • 08:39 ET • 4 min read
Liam Smith boxing betting picks
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Jessie Vargas vs. Liam Smith is scheduled for 12 rounds in the junior middleweight division tonight, April 30, as the chief supporting bout for Amanda Serrano vs. Katie Taylor. This bout features two former champions at the crossroads, with both needing a win to stay relevant.

Former junior middleweight champion Smith has gone 7-2 since a 2016 loss to Saul ‘Canelo’ Alvarez, and is the favorite at -295. Former two-division champion Vargas has been inactive for two years and seeking his first win since 2019 as a +220 underdog.

Here are our free boxing picks and predictions for Vargas vs. Smith on April 30.

Liam Smith vs Jessie Vargas odds

Method of victory Liam Smith Jessie Vargas
Win outright -300 +220
Win by KO/TKO +160 +700
Win by points or decision +165 +380
Draw +1,800 +1,800

Odds courtesy of FanDuel as of April 29, 2022.

Liam Smith vs Jessie Vargas betting predictions

Picks made on April 27, 2022. Click on each pick to jump to the full analysis

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Liam Smith vs Jessie Vargas betting preview

The last time we saw Vargas in the ring was over two years ago in a losing effort against Mikey Garcia. The former two-division champ was outsmarted by the better boxer, but responded after a knockdown to turn a wipeout into a competitive defeat.

Before the Garcia fight, Vargas looked strong in a catchweight bout against Humberto Soto, and figures that the rest and competition at junior middleweight will benefit him here. He's taller than Smith and has faced the stronger opposition over the course of his career.

Smith is the betting favorite here, due to his activity and size advantage. This will be Vargas' first fight at the full division limit after starting off at junior welterweight, whereas Smith has fought his entire career in the division. Smith's defeats came against busy fighters like Alvarez and Jamie Munguia, and he took a close loss to Magomed Kurbanov in May 2021.

One thing about Vargas is that he is tough and has great conditioning. He can make adjustments as the fight wears on, and has good ring acumen in that he doesn’t leave himself open for big shots. He’s shared the ring with excellent fighters, though usually coming up short against them, and has a lot of heart.

While Smith is no slouch, he doesn’t have that extra gear needed to separate himself from the rest of the pack in the deep junior middleweight division. He can be outworked and is lacking a sense of urgency when the fight is slipping away. Smith is also a front-runner, starting off strong and fading over the course of the fight. Vargas is the opposite.

Because Smith isn’t a big puncher, nor does he fight with the type of physical style that could trouble Vargas, this is going to be a conventional battle. How competitive the fight gets depends on when Smith runs out of steam and when Vargas decides to step on the gas.

Liam Smith vs Jessie Vargas picks

Vargas has a 2-1-2 record over his last five fights. That being said, he didn’t look bad in his lone defeat to Garcia, and the argument is that he won the two draws versus Thomas Dulorme and Adrien Broner. Even so, he has been fighting solid opposition and making a good account of himself.

After the Alvarez loss, Smith rebounded on the regional circuit until losing to Munguia, then repeated the cycle before his more recent loss to Kurbanov. One constant in each of those fights was that Smith was outworked and faded late. Vargas has the better gas tank between them, will be fresh after his layoff, and is the superior technician.

A refreshed Vargas should have more energy at a weight class that better suits his 5’11 frame. Coupled with the knowledge that he’s performed admirably against better opposition than Smith makes him that much more attractive as a pick.

Smith may be bigger, but Vargas has a sturdy chin and good survival instincts to get him through rough patches. Also consider that Vargas will have a favorable crowd behind him, and the ingredients are all there for him to spring the upset.

Vargas has never been confused as a big puncher, with 11 stoppages in 29 wins. He’s also fighting in his third weight class, so if he didn’t have KO power then, he isn’t going to have it now.

Vargas wins his fights with technique and activity, so this fight is going the rounds. Smith should remain competitive throughout, so the likelihood of either fighter getting stopped is relatively low.

This is a fight that can go either way, but we are going to find out who wins from the judge’s scorecards and not from a stoppage. Because of that, picking the fight to go the distance is a safe, reliable bet at -128.

One can get nearly double the payout betting on Vargas to win by decision at +380. Vargas has only two stoppages since 2016, so a points win is the logical outcome for him. Taking Vargas by decision is the pick to make as opposed to taking him straight up.

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Danny Howard - Covers.com
Betting Analyst

After a decade of covering all things boxing, from recapping the sport’s biggest fights to sharing behind-the-scenes details of the sweet science, Danny found himself immersed in sports betting, focusing on the sports he knows best. As a boxing and MMA contributor with seasoned experience from growing up around each sport, he can uncover the nuances and intangibles that can make the difference between victory and defeat.

Danny’s work has been mentioned on ESPN and USA Today, and he was a featured guest on The Esportz Network podcast, where he shared his combat sports insights. He is also a published author, with his novel And Stay Down! Boxing’s Worst Comebacks available on Amazon.

Danny is always on the lookout for the best odds and props when it comes to fight night, with Draft Kings and BetMGM being his go-to sites. Danny’s approach to finding value in the theater of the unexpected hinges on the fighters' recent form, especially when considering props.

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