Lakers vs Nuggets Prediction, Picks & Odds for Tonight’s NBA Game

As good as Denver's offense has been in February, Los Angeles matches up well against its Western Conference foes, making LeBron James & Co. a valuable play as road underdogs.

Kenny Ducey - Betting Analyst at Covers
Kenny Ducey • Betting Analyst
Feb 22, 2025 • 16:24 ET • 4 min read
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This article contains predictions for an old game!

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LeBron James Los Angeles Lakers NBA
Photo By - Imagn Images. Los Angeles Lakers forward LeBron James signals to teammates.

The Denver Nuggets are cooking, carrying a nine-game winning streak into tonight’s primetime matchup with the Los Angeles Lakers.

Although the Lakers have yet to find traction following their acquisition of Luka Doncic, my Lakers vs. Nuggets predictions expect their defense to play a pivotal role in pulling off a potential upset in Denver.

Read more in my NBA picks for Saturday, February 22.

Lakers vs Nuggets prediction

My best bet
Lakers +6.5 (-110 at bet365)

My analysis
The Denver Nuggets are on some kind of run, sitting first in offensive efficiency and third in the NBA in net rating over the last three weeks.

The key to Denver’s offensive outburst has been its interior scoring, but the Nuggets have also taken a high volume of shots from the perimeter. Unfortunately for Denver, the Los Angeles Lakers rank fourth in defending the outside shot, which could give them the edge in this matchup.

L.A. will carry a Top-10 frontcourt defense in the league heading into tonight, though its performance in just about every zone has been exceptional. Offensively, the Lakers have taken the fourth-most 3-pointers on average this month and have cashed in at the 11th-best clip, marrying that with the second-best field-goal percentage at the rim.

Denver has been brutal against the 3-pointer this month, allowing almost 37% shooting from outside, and that should allow this Lakers offense to nearly draw level with the Nuggets as they lean on their defense to win this game.

Despite moving Anthony Davis to Dallas a couple of weeks ago, Los Angeles remains a Top-10 team on the glass. As the 3-pointers fall, we may even see Luka Doncic begin to settle in with L.A., and that should give the road team the edge.

Lakers vs Nuggets same-game parlay

Lakers +6.5

LeBron James 3+ threes

Nikola Jokic 10+ assists

I noted above how the Nuggets have struggled against the 3-ball, ranking 21st in field goal percentage allowed and inside the Top 10 in attempts allowed this month. That’s all I need to hear before throwing my money behind LeBron James, who’s shot nearly 40% from outside this year and has cashed in three or more times from outside in six of his last seven.

James has averaged 8.6 3-point attempts per game in his last five contests and has hit this prop in three straight, numbers that will likely go up given the trends we’re seeing.

Meanwhile, the Lakers have allowed the 11th-most assists per 100 possessions this month, and Nikola Jokic has finished with 10+ assists in 12 of his last 17 starts.

Learn how to bet a same-game parlay with these helpful tips and strategies.

Cash your ML bets quicker with bet365's early win payout

Take advantage of the early win payout at bet365, where any pre-game NBA moneyline bet gets paid out as a winner if your team goes up by 20+ points!

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Lakers vs Nuggets odds

Lakers vs Nuggets live odds

Lakers vs Nuggets opening odds

  • Spread: Los Angeles +7 (-105) | Denver -7 (-115)
  • Moneyline: Los Angeles +210 | Denver -260
  • Over/Under: Over 240.5 (-110) | Under 240.5 (-110)

Odds courtesy of bet365

Lakers vs Nuggets spread and Over/Under analysis

  • This line has been ping-ponging between- 6.5 and -7 all day, but has seemed to settle at 6.5 as of this afternoon.
  • The Lakers make up just 45% of the bets but 56% of the handle wagered on the spread.
  • The total has trickled up three full points on Saturday with little resistance.
  • The Under has accounted for 54% of tickets and 58% of the money.

Lakers vs Nuggets trend

Denver has hit the 2Q moneyline in 17 of its last 22 games (+14.40 Units / 37% ROI). Find more NBA betting trends for Lakers vs. Nuggets.

How to watch Lakers vs Nuggets

Location Ball Arena, Denver, CO
Date Saturday, 2-22-2025
Tip-off 8:30 p.m. ET
TV ABC

Lakers vs Nuggets latest injuries

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Kenny Ducey - Covers
Betting Analyst

Kenny Ducey has worked in sports media for more than 10 years and began his journey as a credentialed reporter with Fordham University's WFUV Sports before moving on to Sports Illustrated. There, he wrote about baseball, basketball, and tennis - twice covering the NBA Finals.

He's been in the betting space for seven years, and has established himself as a top expert in MLB and tennis handicapping with brands like Tennis Channel, NBC Sports, and DraftKings. He's also been a frequent guest on betting shows such as MLB's Bettor's Eye and Tennis Bets Live.

Kenny has a knack for identifying underappreciated pitchers and tennis players as moneyline underdogs and credits his unique data analysis and hours of watching sports as the biggest reasons for success through the years. His best advice to bettors? Watch the games, trust your eye, and always question the public narrative.

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