Trail Blazers vs 76ers Prediction, Picks & Odds for Tonight’s NBA Game

Anfernee Simons is the Trail Blazers' primary scoring option and his prowess will be on full display against the chaotic and depleted 76ers.

Quinn Allen - Betting Analyst at Covers.com
Quinn Allen • Betting Analyst
Mar 3, 2025 • 09:52 ET • 4 min read

NBA

Match starts: 3 hrs
PHI
43 %
POR
57 %
EXPERT PICK - PROP
Anfernee Simons o20.5 points (-115) Anfernee Simons o20.5 points (-115)
Read Analysis
Anfernee Simons Portland Trail Blazers NBA
Photo By - Imagn Images.

The Portland Trail Blazers hit the road to visit Tyrese Maxey and the Philadelphia 76ers at the Wells Fargo Center tonight at 7 p.m. ET. 

Anfernee Simons has been showing out lately and I’m eyeing his offensively brilliance to continue here in my Trail Blazers vs 76ers predictions. 

Keep reading for my NBA picks for Monday, March 3 to see why the shooting guard is poised for another big night. 

Trail Blazers vs 76ers prediction

My best bet
Anfernee Simons Over 20.5 points (-115 at bet365)

My analysis
The Portland Trail Blazers may be towards the bottom of the Western Conference, but they have a special talent in Anfernee Simons leading the way. 

The 25-year-old's numbers are down a tad from last season but he’s still playing well. Simons is averaging 18.7 points per game on 36.8% shooting from 3-point land.

Heading into tonight’s matchup with the Philadelphia 76ers, Simons has cashed the Over in points in six of his last 10 outings. He registered 27 points in a tough loss to the Cleveland Cavaliers on Sunday, helping Portland give the Eastern Conference leaders a serious run for their money. 

Simons averaged 19.7 points in February and tends to play better against East teams, putting up 22.9 points compared to 17.1 versus the Western Conference. Also, he produced the goods against the 76ers earlier in the campaign, dropping 25 points.

Philadelphia is poor defensively and allows 22.2 points per contest to shooting guards. On top of that, Simons is averaging 20.3 PPG on back-to-backs. After a standout performance against a much better squad on Sunday, he’ll do his thing again here.

Trail Blazers vs 76ers same-game parlay

Anfernee Simons Over 20.5 points

Tyrese Maxey Under 6.5 assists

Scoot Henderson Over 1.5 threes

Tyrese Maxey is having a wonderful season for the lowly Sixers, averaging 26.7 points, 6.1 assists, and 3.4 rebounds per night. However, the guard has cashed the Under in dimes in five of his last seven games.

Since the All-Star break, Maxey is averaging six assists per night. While there’s the odd game where he’ll drop seven or more, it’s more rare nowadays since he is Philly’s primary scoring option with Joel Embiid lost for the season. While the Blazers are no prize defensively, Maxey had only three assists against them earlier this season.

Scoot Henderson is one of Portland’s top 3-point shooters, averaging 1.6 makes on 4.3 attempts for a 37% clip in 2024-25. He’s been shooting the lights out of the gym lately, cashing the Over in triples in five of his last six appearances.

The 21-year-old was 3-for-5 from long range on Sunday against the Cavs. He’s also shooting it a mile better against the East, averaging 1.9 made treys for a 44% clip. That’s compared to 33% from deep vs. the West. Philadelphia ranks 26th in worst 3-point percentage allowed, too.

Learn how to bet a same-game parlay with these helpful tips and strategies.

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Trail Blazers vs 76ers odds

Trail Blazers vs 76ers live odds

Trail Blazers vs 76ers opening odds

  • Spread: Portland +3.5 (-110) | Philadelphia -3.5 (-110)
  • Moneyline: Portland +140 | Philadelphia -165
  • Over/Under: Over 224.5 (-110) | Under 224.5 (-110)

Odds courtesy of bet365

Trail Blazers vs 76ers spread and Over/Under analysis

  • The Blazers are 4-1 in their last five ATS.
  • Philly has a brutal 1-13 record as an ATS home favorite.
  • The Over has cashed in four straight meetings between Portland and Philadelphia.

Trail Blazers vs 76ers trend

The Portland Trail Blazers have hit the Moneyline in 24 of their last 50 games (+21.70 Units / 38% ROI). Find more NBA betting trends for Trail Blazers vs. 76ers.

How to watch Trail Blazers vs 76ers

Location Wells Fargo Center, Philadelphia, PA
Date Monday, 3-3-2025
Tip-off 7:00 p.m. ET
TV KATU 2.2, NBC Sports Philadelphia

Trail Blazers vs 76ers latest injuries

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Quinn Allen - Covers
Betting Analyst

Quinn Allen is an experienced sports journalist from Vancouver, Canada who fell in love with sports by the time he could walk. He proceeded to play high-level baseball and soccer growing up and eventually played college baseball in the United States.

After his career ended, Quinn received his broadcast journalism degree from BCIT and has since written for many sports publications. He's currently a senior editor at ClutchPoints and has published work for numerous betting websites in the past. 

Quinn's favorite team is Chelsea FC and he'd like to watch a match at Stamford Bridge one day. He loves to bet on NBA player props and encourages others to bet responsibly and not chase losses.

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