March Madness Picks: Expert Predictions & Best Bets for Tonight’s Sweet 16 Games

Our best bet and SGP for every March Madness game happening on Thursday, March 27.

Jared Hochman - Content Manager at Covers.com
Jared Hochman • Content Manager
Mar 27, 2025 • 10:31 ET • 4 min read

We're now into the second weekend of the NCAA Tournament, with the Sweet 16 kicking off tonight.

Our expert March Madness picks start up an exciting weekend of hoops with predictions for each of tonight's four games, including our best bet and favorite same-game parlay.

March Madness picks for Thursday, March 27

6 BYU vs 2 Alabama picks

7:09 p.m. ET | Newark, NJ | CBS

  • Best bet: BYU team total Over 85.5 (-115 at bet365)

  • SGP
    BYU team total Over 85.5
    Alabama alt-team total Over 85.5
    Aden Holloway 2+ threes
    Richie Saunders 5+ rebounds
    (+450 at bet365)

4 Maryland vs 1 Florida picks

7:39 p.m. ET | San Francisco, CA | TBS/truTV

  • Best bet: Alijah Martin Over 13.5 points (+100 at bet365)

  • SGP
    Alijah Martin Over 13.5 points
    Derik Queen 10+ rebounds
    Maryland +6.5
    (+650 at bet365)

Covers BTE – Sweet 16

4 Arizona vs 1 Duke picks

9:39 p.m. ET | Newark, NJ | CBS

  • Best bet: Duke team total Over 81.5 (-120 at bet365)

  • SGP
    Duke team total Over 81.5
    Caleb Love Under 17.5 points
    Tyrese Proctor 2+ threes
    (+300 at bet365)

10 Arkansas vs 3 Texas Tech picks

10:09 p.m. ET | San Francisco, CA | TBS/truTV

Cash your March Madness ML bets quicker with bet365's early win payout

Take advantage of the early win payout at bet365, where any pre-game CBB moneyline bet gets paid out as a winner if your school goes up by 18+ points!

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Jared Hochman Content Manager at Covers.com
Content Manager

Before Jared Hochman joined the Covers team in 2020, he worked for newspaper outlets such as the Chronicle Herald and The Coast, worked in marketing for SkipTheDishes and Vivid Seats, and previously ran a magazine. A journalism graduate from the University of King's College in, Halifax, N.S., "Hoch" brings more than a decade of experience in sports betting, having worked as a freelance handicapper, making appearances on Monumental Sports Network and the Sharp 600 podcast, and now also filling in occasionally as host of Covers' NHL Puck Props. 

Awarded Covers' company MVP for 2023, Jared is an avid bettor of MLB, NFL, NHL, and NBA, while also wagering on some soccer and WNBA. His best advice for sports bettors? Price shop — something he does daily across 10 different sportsbook apps.

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