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We're now into Round 2 of the Big Dance, with a handful of opening round upsets leading to intriguing March Madness odds heading into the first weekend.
We've got the latest odds for each of today's Second Round games, including some high-profile matchups and Cinderellas looking to reach the Sweet 16.
Second Round odds for Saturday, March 22 (early games)
The early slate starts with No. 12 McNeese State looking to pull off another upset, while the highlight is a high-profile coaching matchup between John Calipari and Rick Pitino as Arkansas faces St. John's.
McNeese State vs Purdue odds
12:10 p.m. E.T | Amica Mutual Pavilion, Providence, RI | CBS
- Spread: McNeese State +6.0 (-110) | Purdue -6.0 (-110)
- Total: Over 142.5 (-110) | Under 142.5 (-110)
- Moneyline: McNeese State +210 | Purdue -260
Arkansas vs St. John’s odds
2:40 p.m. E.T | Amica Mutual Pavilion, Providence, RI | CBS
- Spread: Arkansas +7.5 (-110) | St. John’s -7.5 (-110)
- Total: Over 144.5 (-110), Under 144.5 (-110)
- Moneyline: Arkansas +260 | St. John’s -320
Michigan vs Texas A&M odds
5:15 p.m. E.T | Ball Arena, Denver, CO | CBS
- Spread: Michigan +3.0 (-110) | Texas A&M -3.0 (-110)
- Total: Over 141.0 (-110) | Under 141.0 (-110)
- Moneyline: Michigan +130 | Texas A&M -155
Drake vs Texas Tech odds
6:10 p.m. E.T | INTRUST Bank Arena, Wichita, KS | TNT
- Spread: Drake +7.0 (-110) | Texas Tech -7.0 (-110)
- Total: Over 127.0 (-110) | Under 127.0 (-110)
- Moneyline: Drake +260 | Texas Tech -320
Expert March Madness picks
Looking for the best bets to make this March? Covers has you, well, covered with all our free expert March Madness picks — right through to the National Championship!
Second Round odds for Saturday, March 22 (late games)
Today's late session is highlighted by two No. 1 seeds in action, with Auburn facing Creighton and Houston taking on Gonzaga, with the nightcap featuring Tennessee against UCLA.
Creighton vs Auburn odds
7:10 p.m. E.T | Rupp Arena, Lexington, KY | TBS/truTV
- Spread: Creighton +9.0 (-110) | Auburn -9.0 (-110)
- Total: Over 151.0 (-110) | Under 151.0 (-110)
- Moneyline: Creighton +350 | Auburn -450
BYU vs Wisconsin odds
7:45 p.m. E.T | Ball Arena, Denver, CO | CBS
- Spread: BYU +1.0 (-110) | Wisconsin -1.0 (-110)
- Total: Over 155.5 (-110) | Under 155.5 (-110)
- Moneyline: BYU -105 | Wisconsin -115
Gonzaga vs Houston odds
8:40 p.m. E.T | INTRUST Bank Arena, Wichita, KS | TNT
- Spread: Gonzaga +5.5 (-110) | Houston -5.5 (-110)
- Total: Over 139.5 (-110) | Under 139.5 (-110)
- Moneyline: Gonzaga +195 | Houston -240
UCLA vs Tennessee odds
9:40 p.m. E.T | Rupp Arena, Lexington, KY | TBS
- Spread: UCLA +5.0 (-110) | Tennessee -5.0 (-110)
- Total: Over 131.0 (-110) | Under 131.0 (-110)
- Moneyline: UCLA +185 | Tennessee -225
Not intended for use in MA.
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