UConn vs UCLA Prediction, Picks & Odds for Tonight's Women’s March Madness Final Four Game

Quinones' prediction: The Huskies will win, but the Bruins will cover the spread in a highly competitive Final Four showdown.

Aisha Quiñones - Senior Publishing Editor at Covers
Aisha Quiñones • Senior Publishing Editor
Apr 4, 2025 • 18:20 ET • 4 min read
Paige Bueckers Kiki Rice WNCAAB
Photo By - Imagn Images. UConn Huskies guard Paige Bueckers and UCLA Bruins guard Kiki Rice.

One of the biggest matchups in the Women's NCAA Tournament has come to fruition with the No. 1 UCLA Lady Bruins facing the No. 2 UConn Lady Huskies tonight. It's a tale of two teams with completely different narratives stepping into the Final Four.

On one hand, Paige Bueckers and the Huskies are running through opponents with ease and making headlines, while Lauren Betts and the Bruins are leaving their mark on UCLA history.

However, even at the tail end of the tournament, the Bruins continue to remain slept on.

What will it take for people to wake up and see what the UCLA Bruins are doing? Defeating a team like the Huskies would certainly do the trick. 

Let's get into my UConn vs. UCLA predictions and March Madness picks for Friday, April 4.

Who will win UConn vs UCLA?

The incredible run by the UCLA Bruins comes to an end here. The Huskies are just too good. Sure, we all love an upset and that's what make the Women's NCAA Tournament even greater, but that won't be the case in this Final Four matchup.

However, that doesn't mean you should underestimate the Bruins. They've been overlooked and underappreciated throughout the tournament and have made it to their first Final Four in program history. 

They're motivated. They're ready to prove a point. And they're fed up with not receiving the credit that they rightfully deserve, but teams that have played under Geno Auriemma have never been the type to get cocky or dismiss an opponent.

Count on the Huskies to get one game closer to cutting down the nets.

UConn vs UCLA prediction

My best bet: UCLA +7.5 (-110 at bet365)

My analysis
The biggest test for the UConn Lady Huskies in this matchup is similar to what they faced when they took on Raegan Beers and the Oklahoma Sooners: keeping up in the post.

Lauren Betts is the UCLA version of that challenge. Still, this time, this is a dominant post player on a team that has the experience of pulling off major upsets (i.e., defeating the South Carolina Gamecocks in the regular season).

Will that type of upset be made in this contest? I doubt it.

The Huskies have freshmen such as Jana El Alfy and Sarah Strong with room to grow in that position and put up a solid fight against an experienced player such as Betts.

They've shown that they can adjust on the fly to weather whatever storm they encounter.

Besides that, the Huskies have this all lined up in their favor but expect the Bruins keep it close enough to bet on their spread.

UConn vs UCLA same-game parlay (SGP)

UConn moneyline

Over 135 

UCLA +7.5

The Huskies didn't make it this far just to lie down and come up short. Don't get me wrong, the Bruins have what it takes to take advantage of UConn in the post and having the offensive weapons to keep up, but the experience of UConn is just too good to pass up on the moneyline here.

The weapons that I speak of? Well, it's obvious from Paige Bueckers, Lauren Betts, Azzi Fudd, Kiki Rice, Sarah Strong and that's just to name a few. Each side brings the heat to have this total meet the Over.

Much like my previous point, these two teams are no slouch and this one will a matchup that you'll want to grab your popcorn for as the Bruins will make it interesting for the Huskies throughout all four quarters.

Learn how to bet a same-game parlay with these helpful tips and strategies.

Cash your ML bets quicker with bet365's early win payout

Take advantage of the early win payout at bet365, where any pre-game CBB moneyline bet gets paid out as a winner if your school goes up by 18+ points!

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UConn vs UCLA opening odds

  • Spread: UConn -8.5 (-105) | UCLA +8.5 (-115)
  • Moneyline: UConn -425 | UCLA +325
  • Over/Under: Over 135.5 (-110) | Under 135.5 (-110)

Odds courtesy of bet365.

How to watch UConn vs UCLA

Location Amalie Arena, Tampa, FL
Date Friday, 4-4-2025
Tip-off 9:00 p.m. ET
TV ESPN

UConn vs UCLA key injuries

UConn : No key injuries.
UCLA : No key injuries.

Not intended for use in MA.
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Aisha Quiñones - Covers
Senior Publishing Editor

Hailing from Harlem, New York, Aisha Quiñones joined Covers in 2024 after an illustrious career with several other major media outlets. A proud Johnnie, after graduating from the Big East basketball powerhouse St. John's University, Quiñones earned her bachelor's degree in sport management and journalism, then obtained her master's degree in media studies from The New School.

Over a span of 12+ years, Quiñones has built her portfolio as a writer, dipped her toe into on-camera work, and also been behind the scenes in producing sports content.

Despite being a New Yorker, Quiñones has always been a lifelong Los Angeles Lakers fan thanks to her mom's joy of watching Kobe Bryant play — so much of a fan to the point that Quiñones named her toy poodle after the late-great legend.

Her hometown roots stay true to her MLB and WNBA choice in teams, as a Yankees and Liberty fan, due to her uncle and grandmother's love for the sports throughout her childhood.

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