Marquette vs Iowa State Prediction, Picks, and Odds for Tonight’s College Basketball Game

A battle of Top-10 programs takes place in Ames tonight, and we expect Kam Jones & Co. to keep pace with the Cyclones at Hilton Coliseum.

Ed Scimia - Betting Analyst at Covers.com
Ed Scimia • Betting Analyst
Dec 4, 2024 • 13:05 ET • 4 min read
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This article contains predictions for an old game!

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Two of the top teams in the country will face off on Wednesday night as the Iowa State Cyclones host the Marquette Golden Eagles in one of the premier matchups of the Big 12-Big East Battle.

Both teams have looked good so far, but the Golden Eagles are more battle-tested at this point, and that’s why I like them to cover in my Marquette vs. Iowa predictions.

I’ll dig into the matchup below and offer up my best bets in my free college basketball picks for Wednesday, December 4.

Marquette vs Iowa State prediction

My best bet
Marquette +5.5 (-110 at bet365)

My analysis

Marquette is off to an impressive 8-0 start, and that success has come against competitive programs. In mid-November, the Golden Eagles scored wins over Maryland, Purdue, and Georgia. That was a stretch of three games with single-digit spreads, and Marquette covered in all three outings.

Early in the season, Marquette appears to be developing an identity as one of the toughest defensive squads in the country. The Golden Eagles are allowing 63.6 points per game to their opponents, currently ranked sixth in adjusted defensive rating according to KenPom.

That defense will be tested in Ames, as Iowa State is shooting an impressive 50.9% from the field this season. However, Marquette also has the firepower to keep up with the Cyclones if this game turns into more of a shootout.

Senior guard Kam Jones (19.6 ppg) is one of the better scorers in the country, and he’s joined by three other players who are averaging double digits. Overall, the Golden Eagles are averaging a healthy 84.5 ppg and put up 76+ points in each of their three contests against major conference opponents this season.

Meanwhile, Iowa State's 19th-ranked defense rating is mostly thanks to blowout wins against outgunned mid-majors. The Cyclones are also 2-4 against the spread this year, with one of those wins coming as an underdog against Auburn. As good as the Cyclones have been, they’ve come up a little short of expectations set by bookmakers, and Marquette is 6-2 ATS this year — including winning outright the only other time they were underdogs.

This should be a very tight game that hangs in the balance in the final minutes. I’m not turning down the handful of points I can get on Marquette. 

Marquette vs Iowa State same-game parlay

Marquette +5.5

Over 150.5

Kam Jones 20+ points

Along with taking Marquette to cover, I’ll also take a bet on the Over at a reasonable total tonight. Both teams are riding streaks of hitting the Over, and both offenses are accustomed to going above 80 points, so we should be able to eclipse this O/U. 

For the Golden Eagles, I'm backing Kam Jones to score 20+ points tonight. Jones has hit that total in four of his first eight games, and he should shine in a high-scoring game. 

Learn how to bet a same-game parlay with these helpful tips and strategies.

Cash your ML bets quicker with bet365's early win payout

Take advantage of the early win payout at bet365, where any pre-game CBB moneyline bet gets paid out as a winner if your school goes up by 18+ points!

Learn more about this feature, and all of bet365's offerings, with our comprehensive bet365 review.

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Marquette vs Iowa State odds

Marquette vs Iowa State live odds

Marquette vs Iowa State opening odds

  • Spread: Marquette +6 | Iowa State -6
  • Moneyline: Marquette +210 | Iowa State -260
  • Over/Under: Over 152.5 | Under 152.5

Odds courtesy of bet365

Marquette vs Iowa State betting trend to know

The Golden Eagles are 4-1 ATS in their last five games overall. Find more college basketball betting trends for Marquette vs. Iowa State.

How to watch Marquette vs Iowa State

Location: Hilton Coliseum, Ames, IA
Date: Wednesday, 12-4-2024
Tip-off: 8:00 p.m. ET
TV: ESPN+

Marquette vs Iowa State key injuries

Not intended for use in MA.
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Ed Scimia - Covers.com
Betting Analyst

Ed Scimia has been writing about the gaming industry for over 15 years. He graduated from Syracuse University with degrees in Magazine Journalism and Political Science in 2003, and has covered major gambling events like the World Series of Poker in his career. Since joining Covers in 2022, Ed has offered his sports betting analysis primarily on MLB, NFL, college football, and college basketball games, but is willing to take on any sport.

His betting strategy focuses more on finding line value based on deviations from the market rather than traditional handicapping, primarily shopping between DraftKings, FanDuel, and Fanatics in his home state of Connecticut, though he’s not afraid to do deep game analysis to find profitable bets at any book.

Outside of gambling, Ed is an avid curler who competes in mixed doubles on the World Curling Tour and runs a popular curling YouTube channel, Chess on Ice. That experience has come in handy during the Olympics, when he has proven to be a successful curling bettor as well. 

Ed's advice to new bettors is to always open multiple sportsbook accounts and check the odds at each before placing any bet. Successful sports betting is about consistently beating the closing line value, which requires finding spots where one book is offering odds far better than the rest of the market and jumping on those opportunities.

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